CAS 118292-36-7

Metil (2R,8S)-8-(clorometil)-1,2,3,6,7,8-hexahidro-4-hidroxi-2-metil-1-oxo-6-[(5,6,7-trimetoxi-1H-indol-2-il)carbonil]benzo[1,2-b:4,3-b′]dipirrol-2-carboxilato

Descripción:

Metil (2R,8S)-8-(clorometil)-1,2,3,6,7,8-hexahidro-4-hidroxi-2-metil-1-oxo-6-[(5,6,7-trimetoxi-1H-indol-2-il)carbonil]benzo[1,2-b:4,3-b′]dipirrol-2-carboxilato, con número CAS 118292-36-7, es un compuesto orgánico complejo caracterizado por su intrincada estructura molecular, que incluye múltiples grupos funcionales como hidroxilo, carbonilo y ésteres. Este compuesto presenta un marco de dipirrol hexahidro, lo que indica una estructura cíclica saturada, e incorpora un grupo clorometilo, lo que sugiere una reactividad potencial y aplicaciones en la síntesis química posterior. La presencia de trimetoxindol sugiere actividad biológica, posiblemente relacionada con la química medicinal, ya que los derivados de indol a menudo están asociados con diversas propiedades farmacológicas. La estereoquímica indicada por la configuración (2R,8S) resalta la naturaleza quiral del compuesto, lo que puede influir en sus interacciones biológicas y eficacia. En general, las características estructurales únicas y los grupos funcionales de este compuesto pueden contribuir a sus aplicaciones potenciales en productos farmacéuticos o como un químico de investigación en síntesis orgánica.

Fórmula: C₂₆H₂₆ClN₃O₈

InChI: InChI=1S/C26H26ClN3O8/c1-26(25(34)38-5)23(32)18-17-12(9-27)10-30(14(17)8-15(31)20(18)29-26)24(33)13-6-11-7-16(35-2)21(36-3)22(37-4)19(11)28-13/h6-8,12,28-29,31H,9-10H2,1-5H3/t12-,26-/m1/s1

Clave InChI: InChIKey=BOGFADYROAVVTF-MZHQLVBMSA-N

SMILES: C(Cl)[C@H]1C=2C3=C(N[C@](C(OC)=O)(C)C3=O)C(O)=CC2N(C(=O)C=4NC=5C(C4)=CC(OC)=C(OC)C5OC)C1

Sinónimos:

• (+)-Duocarmycin C₂
• Antibiotic SF 2582A
• Benzo[1,2-b:4,3-b′]dipyrrole-2-carboxylic acid, 8-(chloromethyl)-1,2,3,6,7,8-hexahydro-4-hydroxy-2-methyl-1-oxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-, methyl ester, (2R,8S)-
• Benzo[1,2-b:4,3-b′]dipyrrole-2-carboxylic acid, 8-(chloromethyl)-1,2,3,6,7,8-hexahydro-4-hydroxy-2-methyl-1-oxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-, methyl ester, (2R-trans)-
• Methyl (2R,8S)-8-(chloromethyl)-1,2,3,6,7,8-hexahydro-4-hydroxy-2-methyl-1-oxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]benzo[1,2-b:4,3-b′]dipyrrole-2-carboxylate
• Pyrindamycin
• Sf 2582A
• methyl (2R,8S)-8-(chloromethyl)-4-hydroxy-2-methyl-1-oxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-1,2,3,6,7,8-hexahydropyrrolo[3,2-e]indole-2-carboxylate
• pyrindamycin A
• Duocarmycin C2

Pyrindamycin A

CAS: 118292-36-7

Pyrindamycin A is an antibiotic that inhibits DNA synthesis,and shows antitumor activities against murine leukemia.

Fórmula: C₂₆H₂₆ClN₃O₈

Pureza: 98%

Forma y color: Solid

Peso molecular: 543.95

Ref: TM-T12590

Pyrindamycin A

CAS: 118292-36-7

Pyrindamycin A is a natural product that is the product of a fermentation process. It has been shown to have cytotoxic properties and can be used as a chemotherapeutic agent for leukemia and other cancers. Pyrindamycin A is also an antibacterial, with activity against gram-positive and gram-negative bacteria. The mechanism of action involves steric interactions with the target tissue, leading to morphological changes in the bacterial cell wall by inhibiting the synthesis of peptidoglycan. Pyrindamycin A has been shown to inhibit leukemia inhibitory factor (LIF) production in mouse bone marrow cells, which may be due to its ability to bind to DNA. This molecule also has biological properties that are similar to those of monoclonal antibodies, including binding and inhibition of protein synthesis in sensitive cells.

Fórmula: C₂₆H₂₆ClN₃O₈

Pureza: Min. 95%

Peso molecular: 544 g/mol

Ref: 3D-TEA29236