CAS 1188-21-2

N-Acetil-L-leucina

Descripción:

N-Acetil-L-leucina es un derivado acetilado del aminoácido leucina, caracterizado por su fórmula estructural que incluye un grupo acetilo unido al nitrógeno de la cadena lateral de la leucina. Este compuesto es un polvo cristalino blanco a blanco sucio, soluble en agua y disolventes orgánicos, lo que lo hace versátil para diversas aplicaciones. N-Acetil-L-leucina es conocido por su papel en procesos bioquímicos y a menudo se estudia por sus posibles efectos terapéuticos, particularmente en el contexto de condiciones neurológicas y trastornos metabólicos. También puede servir como un bloque de construcción en la síntesis de péptidos y como un auxiliar quiral en la síntesis orgánica. El compuesto exhibe estabilidad en condiciones estándar, aunque debe almacenarse en un lugar fresco y seco para mantener su integridad. Al igual que con muchos derivados de aminoácidos, es importante manejar N-Acetil-L-leucina con cuidado, siguiendo las pautas de seguridad adecuadas para evitar cualquier peligro potencial asociado con la exposición química.

Fórmula: C₈H₁₅NO₃

InChI: InChI=1S/C8H15NO3/c1-5(2)4-7(8(11)12)9-6(3)10/h5,7H,4H2,1-3H3,(H,9,10)(H,11,12)/t7-/m0/s1

Clave InChI: InChIKey=WXNXCEHXYPACJF-ZETCQYMHSA-N

SMILES: [C@@H](CC(C)C)(NC(C)=O)C(O)=O

Sinónimos:

• (-)-N-Acetyl-<span class="text-smallcaps">L</span>-leucine
• (2S)-2-(acetylamino)-4-methylpentanoate
• (2S)-2-Acetamido-4-methylpentanoic acid
• (S)-2-Acetamido-4-methylpentanoic acid
• <span class="text-smallcaps">L</span>-Leucine, N-acetyl-
• Ac-Leu-OH
• Acetyl-<span class="text-smallcaps">L</span>-leucine
• Acetylleucine
• Leucine, N-acetyl-, <span class="text-smallcaps">L</span>-
• N-acetylleucine
• NSC 206316
• Leucine, N-acetyl-, L-
• Acetyl-L-leucine
• N-Acetyl-L-leucine

N-Acetyl-L-leucine

CAS: 1188-21-2

Fórmula: C₈H₁₅NO₃

Pureza: >99.0%(T)

Forma y color: White to Almost white powder to lump

Peso molecular: 173.21

Ref: 3B-A0098

N-Acetyl-L-leucine, 99%

CAS: 1188-21-2

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₈H₁₅NO₃

Pureza: 99%

Forma y color: White, Crystals or powder or crystalline powder

Peso molecular: 173.21

Ref: 02-L13926

N-Acetyl-L-leucine

CAS: 1188-21-2

Fórmula: C₈H₁₅NO₃

Pureza: 95%

Forma y color: Solid

Peso molecular: 173.2096

Ref: IN-DA0035C1

N-Acetyl-L-leucine

CAS: 1188-21-2

Fórmula: C₈H₁₅NO₃

Peso molecular: 173.21

Ref: 7W-GM6611

N-Acetyl-L-leucine

CAS: 1188-21-2

N-Acetyl-L-leucine

Pureza: ≥98%

Peso molecular: 173.21g/mol

Ref: 54-BUP18435

N-Acetyl-L-leucine

CAS: 1188-21-2

N-Acetyl-L-leucine

Fórmula: C₈H₁₅NO₃

Forma y color: white crystalline powder

Peso molecular: 173.21g/mol

Ref: 54-BIA1765

N-Acetyl-L-leucine

CAS: 1188-21-2

N-Acetylleucine, a water-soluble, weakly acidic derivative of leucine, is found in biofluids like feces and saliva.

Fórmula: C₈H₁₅NO₃

Pureza: 99.89%

Forma y color: Solid

Peso molecular: 173.21

Ref: TM-T4798

N-Acetyl-L-(-)-leucine

CAS: 1188-21-2

Applications N-Acetyl-L-(-)-leucine is used in the preparation of small molecule inhibitors of anti-apoptotic Bcl-2 family proteins. Also used in the preparation of amphiphilic copolymers involving hydrophobic amino acid and oligopeptide side chains for optical tumor imaging in vivo.
References Zheng, C. et al.: Bioorg. Med. Chem. Lett., 22, 39 (2012); Miki, K. et al.: Bull. Chem. Soc. Jap., 85, 1277 (2012);

Fórmula: C₈H₁₅NO₃

Forma y color: Neat

Peso molecular: 173.21

Ref: TR-A185035

N-Acetyl-L-leucine

CAS: 1188-21-2

N-Acetyl-L-leucine is a natural amino acid that has been shown to have therapeutic potential in the treatment of neurodegenerative diseases. N-acetyl-L-leucine binds to DNA duplexes and inhibits the formation of protein aggregates, which are associated with neurodegenerative disorders. N-acetyl-L-leucine also has a high affinity for neuronal receptors, which may be due to its basic nature. In addition, this compound is able to inhibit oxidative stress induced by glutamate and nitric oxide, as well as mitochondrial membrane potential loss. It also protects against neuronal death induced by amide or cytosolic Ca2+.

Fórmula: C₈H₁₅NO₃

Forma y color: White Powder

Peso molecular: 173.21 g/mol

Ref: 3D-FA10862

Ac-Leu-OH

CAS: 1188-21-2

M03063 - Ac-Leu-OH

Fórmula: C₈H₁₅NO₃

Pureza: 95%

Forma y color: Solid, Crystalline

Peso molecular: 173.212

Ref: 10-M03063

N-Acetyl-L-Leucine extrapure, 99%

CAS: 1188-21-2

Fórmula: C₈H₁₅NO₃

Pureza: min. 99%

Forma y color: White, Crystalline powder

Peso molecular: 173.21

Ref: SR-76097

N-Acetyl-L-Leucine (Acetyl-L-leucine)

CAS: 1188-21-2

Acyclic amides (including acyclic carbamates) and their derivatives and salts thereof, nesoi

Fórmula: C₈H₁₅NO₃

Forma y color: White Powder

Peso molecular: 173.10519

Ref: 45-1010081