CAS 1191237-69-0
:(2R,3R,4S,5R)-2-(4-aminopirrolo[1,2-f][1,2,4]triazin-7-il)-3,4-dihidroxi-5-(hidroximetil)tetrahidrofurano-2-carbonitrilo
Descripción:
La sustancia química con el nombre "(2R,3R,4S,5R)-2-(4-aminopirrolo[1,2-f][1,2,4]triazin-7-il)-3,4-dihidroxi-5-(hidroximetil)tetrahidrofurano-2-carbonitrilo" y el número CAS "1191237-69-0" es un compuesto orgánico complejo caracterizado por su estereoequilibrio específico y grupos funcionales. Presenta un anillo de tetrahidrofurano, que es un éter cíclico de cinco miembros, y contiene múltiples grupos hidroxilo (-OH) que contribuyen a su hidrofobicidad y potencial reactividad. La presencia de un grupo carbonitrilo (-C≡N) indica un potencial para reacciones nucleofílicas, mientras que la porción aminopirrolo-triazina sugiere actividad biológica, posiblemente como agente farmacéutico. La configuración estereoespecífica (2R,3R,4S,5R) implica que el compuesto tiene disposiciones espaciales específicas que pueden influir en su interacción con objetivos biológicos. En general, este compuesto puede exhibir propiedades interesantes en química medicinal, particularmente en el desarrollo de terapias dirigidas a vías biológicas específicas. Su solubilidad, estabilidad y reactividad se verían influenciadas por los grupos funcionales y la estructura molecular general.
- (2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
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Encontrado 12 productos.
Remdesivir Impurity 34 (GS 441524)
CAS:Fórmula:C12H13N5O4Forma y color:White To Off-White SolidPeso molecular:291.27(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]Triazin-7-yl)-3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-Carbonitrile
CAS:(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]Triazin-7-yl)-3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-CarbonitrilePureza:98%Peso molecular:291.26g/molGS-441524
CAS:GS-441524 treatment of cats with naturally occurring feline infectious peritonitis.Fórmula:C12H13N5O4Pureza:98.78% - 99.75%Forma y color:SolidPeso molecular:291.26Remdesivir Impurity 34-13C-d3-15N2 (GS-441524-13C-d3-15N2)
CAS:Fórmula:C1113CH10D3N315N2O4Peso molecular:297.26GS-441524 (Remdesivir Metabolite)
CAS:Fórmula:C12H13N5O4Pureza:≥ 98.0%Forma y color:White to off-white powderPeso molecular:291.26(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
CAS:Applications (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile is a predominant metabolite of remdesivir with great potential for Covid-19 treatment.
References Yan, V. C., et al.: ACS Med. Chem., 11, 1361 (2020)Fórmula:C12H13N5O4Forma y color:NeatPeso molecular:291.2627Remdesivir impurity 7
CAS:Remdesivir is an antiviral drug. It is an RNA-dependent RNA polymerase inhibitor that has been shown to be effective against a broad range of RNA viruses, including influenza A and B, rhinovirus, respiratory syncytial virus, and parainfluenza virus. Remdesivir impurity 7 (impurity) is a byproduct of the synthesis process of remdesivir. It is a white crystalline solid with a strong chemical odor. This impurity can be synthesized in high purity as well as in custom specifications to meet the needs of pharmaceutical companies developing new drugs.
Fórmula:C15H24NO5PPureza:Min. 95%Peso molecular:329.33 g/molGS 441524
CAS:Nucleoside analog with antiviral activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is a pro-drug and undergoes intracellular phosphorylation resulting in the active triphosphate metabolite. The triphosphorylated GS 441524 analog competes with natural nucleoside triphosphates and interferes with viral RNA synthesis. In previous studies it was tested in vitro as well as in experimental animals and showed good safety profile.Fórmula:C12H13N5O4Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:291.26 g/mol(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
CAS:Fórmula:C12H13N5O4Pureza:98%Peso molecular:291.267
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