CAS 119418-04-1

galanina humana

Descripción:

La galanina es un neuropéptido que desempeña un papel significativo en varios procesos fisiológicos, incluida la regulación del estado de ánimo, el apetito y la percepción del dolor. La forma humana de la galanina, identificada por el número CAS 119418-04-1, está compuesta por una secuencia de aminoácidos que le permite interactuar con receptores específicos de galanina en el cuerpo. Esta interacción es crucial para mediar sus efectos en la neurotransmisión y la regulación hormonal. La galanina se expresa principalmente en el sistema nervioso central y en tejidos periféricos, influyendo en funciones como la neuroprotección, la neurogénesis y la modulación de las respuestas al estrés. También está involucrada en la regulación de los ritmos circadianos y se ha implicado en diversas condiciones patológicas, incluida la depresión y la obesidad. El péptido se caracteriza por su tamaño relativamente pequeño y flexibilidad estructural, lo que contribuye a su capacidad para unirse a múltiples subtipos de receptores. En general, la galanina sirve como una importante molécula de señalización con diversas funciones biológicas, lo que la convierte en un tema de interés tanto en la investigación básica como clínica.

Fórmula: C₁₃₉H₂₁₀N₄₂O₄₃

Sinónimos:

• H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Val-Gly-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-Asn-Gly-Leu-Thr-Ser-OH

Galanin (human)

CAS: 119418-04-1

Human galanin, a 30-amino acid non-amidated peptide, has originally been isolated from colon and pituitary. Its sequence differs from that of rat and porcine galanins by 4 and 6 amino acids in the C-terminal moiety, respectively. Synthetic human galanin is equipotent to the rat peptide in the isolated rat fundus muscle strip bioassay. Both peptides also fully activate the rat galanin receptor, indicating the importance of the conserved N-terminal portion of galanin for receptor interaction. Galanin, which is widely distributed in the CNS, and GAL receptors (GALR) are overexpressed in limbic brain regions associated with cognition in Alzheimer disease. As galanin inhibits acetylcholine release, galanin antagonists have gained interest in AD research.

Fórmula: C₁₃₉H₂₁₀N₄₂O₄₃

Pureza: 96.2%

Forma y color: White Powder

Peso molecular: 3157.45

Ref: 01-4013896

Galanin (human)

CAS: 119418-04-1

Galanin has been shown to inhibit acetylcholine release, glutamate release and carbachol-stimulated phosphatidylinositol hydrolysis in the hippocampus. The peptide hormone is also linked to behavioral and cognitive deficits in Alzheimer’s disease.

Fórmula: C₁₃₉H₂₁₀N₄₂O₄₃

Pureza: 98.2%

Forma y color: White

Peso molecular: 3157.45

Ref: 01-4095896

Galanin, human

CAS: 119418-04-1

Fórmula: C₈₅H₁₃₃N₂₉O₂₅

Pureza: 97%

Peso molecular: 1961.1448

Ref: IN-DA008R27

Galanin (1-30), human

CAS: 119418-04-1

Galanin (1-30), human is a neuropeptide agonist for GalR1/R2 receptors with 1 nM affinity, influencing endocrine, metabolism, and neurotransmission.

Fórmula: C₁₃₉H₂₁₀N₄₂O₄₃

Pureza: 98%

Forma y color: Solid

Peso molecular: 3157.46

Ref: TM-TP1732

Galanin (Human)

CAS: 119418-04-1

Galanin is a peptide that belongs to the family of neuropeptides and is found in the endocrine system, the central and peripheral nervous systems. It has been shown to inhibit the release of acetylcholine in the central nervous system and interestingly in Alzheimer’s disease patients, hyperinervation of galanin fibres has been found. Galanin is also known to have a variety of physiological effects including inhibition of insulin release, stimulation of prolactin and growth hormone secretion and it also plays a role in feeding, mood, cognition, neuroendocrine regulation and affects gastrointestinal motility. Galanin asserts its effects through associated with G-protein coupled receptors. This product is available as a 0.5mg vial.

Fórmula: C₁₃₉H₂₁₀N₄₂O₄₃

Pureza: Min. 95%

Peso molecular: 3,157.4 g/mol

Ref: 3D-PGA-4245-V

Galanin (human) trifluoroacetate salt

CAS: 119418-04-1

Please enquire for more information about Galanin (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Fórmula: C₁₃₉H₂₁₀N₄₂O₄₃

Pureza: Min. 95%

Peso molecular: 3,157.41 g/mol

Ref: 3D-FG110297