CAS 119478-56-7

Meropenem trihidrato

Descripción:

Meropenem trihidrato es un antibiótico de amplio espectro que pertenece a la clase de los carbapenemes, utilizado principalmente para tratar infecciones bacterianas severas. Se caracteriza por su capacidad para inhibir la síntesis de la pared celular bacteriana, lo que lo hace efectivo contra una amplia gama de bacterias Gram-positivas y Gram-negativas, incluidas aquellas resistentes a otros antibióticos. La forma de trihidrato indica que el compuesto contiene tres moléculas de agua por cada molécula de meropenem, lo que puede influir en su solubilidad y estabilidad. El meropenem se administra típicamente por inyección intravenosa debido a su baja biodisponibilidad oral. Es conocido por sus favorables propiedades farmacocinéticas, que incluyen una vida media relativamente larga y buena penetración en los tejidos. Los efectos secundarios comunes pueden incluir trastornos gastrointestinales, dolor de cabeza y posibles reacciones alérgicas. Al igual que con otros antibióticos, la aparición de resistencia es una preocupación, lo que requiere un uso cuidadoso y adherencia a los regímenes prescritos. En general, Meropenem trihidrato es una opción crítica en el tratamiento de infecciones graves, particularmente en entornos hospitalarios.

Fórmula: C₁₇H₂₅N₃O₅S

InChI: InChI=1/C17H25N3O5S/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4/h7-12,18,21H,5-6H2,1-4H3,(H,24,25)/t7-,8+,9-,10-,11-,12-/m0/s1

Clave InChI: InChIKey=CTUAQTBUVLKNDJ-OBZXMJSBSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@@]([C@@H](C)O)(C2=O)[H])([C@@H](C)C1S[C@H]3C[C@@H](C(N(C)C)=O)NC3)[H].O

Sinónimos:

• (4R,5S,6S)-3-[[(3S,5S)-5-(Dimethylcarbamoyl)-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid trihydrate
• (4R,5S,6S)-3-[[(3S,5S)-5-(Dimethylcarbamoyl)pyrrolidin-3-yl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• (4R,5S,6S)-3-{[(2S,5S)-5-(dimethylcarbamoyl)pyrrolidin-2-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid trihydrate
• (4S,5R,6R)-3-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, hydrate (1:3), (4R,5S,6S)-
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, trihydrate, (4R,5S,6S)-
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-, trihydrate, [4R-[3(3S*,5S*),4α,5β,6β(R*)]]-
• Meropenem (with carbonate)
• Meropenem trihydrate
• Meropenem
• 3-[[5-[(Dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3,2,0]hept-2-ene-2-carboxylic acid trihydrate
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-, trihydrate, [4R-[3(3S*,5S*),4a,5b,6b(R*)]]-(9CI)
• MEROPENEM WITH SODIUM CARBONATE
• MEROPENEM
• MEROPENEMTRIHYDRATE(3-[[5-[(DIMETHYLAMINO)CARBONYL]-3-PYRROLIDINYL]THIO]-6-(1-HYDROXYETHYL)-4-METHYL-7-OXO-1-AZABICYCLO[3,2,0]HEPT-2-ENE-2-CARBOXYLICACIDTRIHYDRATE)

Meropenem Trihydrate

CAS: 119478-56-7, 96036-03-2

Fórmula: C₁₇H₂₅N₃O₅S·3H₂O

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 437.51

Ref: 3B-M2279

Meropenem trihydrate, 98-101%

CAS: 119478-56-7

A broad spectrum antibiotic targeting a wide range of bacteria

Fórmula: C₁₇H₃₁N₃O₈S

Pureza: 98-101%

Forma y color: Powder or crystals or crystalline powder, White to pale yellow

Peso molecular: 437.51

Ref: 02-J66446

MEROPENEM TRIHYDRATE CRS

CAS: 119478-56-7

MEROPENEM TRIHYDRATE CRS

Fórmula: C₁₇H₂₅N₃O₅S

Forma y color: Added Modified

Peso molecular: 383.4625

Ref: 41-Y0001252

Meropenem

CAS: 119478-56-7

Antibiotics nesoi

Fórmula: C₁₇H₂₅N₃O₅S·3H₂O

Forma y color: White Light Yellow Powder

Peso molecular: 437.51

Ref: 45-1392454

(4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid trihydrate

CAS: 119478-56-7

Fórmula: C₁₇H₃₁N₃O₈S

Pureza: 97%

Forma y color: Solid

Peso molecular: 437.5083

Ref: IN-DA000IV3

Meropenem trihydrate

CAS: 119478-56-7

Meropenem trihydrate (SM 7338 trihydrate) with broad-spectrum antibacterial activity,is a carbapenem antibiotic.

Fórmula: C₁₇H₃₁N₃O₈S

Pureza: 99.80%

Forma y color: Solid

Peso molecular: 437.51

Ref: TM-T12004

Meropenem trihydrate

CAS: 119478-56-7

Fórmula: C₁₇H₂₅N₃O₅S·3H₂O

Pureza: ≥ 98.0% (anhydrous basis)

Forma y color: White, off-white or faint beige crystalline powder

Peso molecular: 437.51

Ref: 7W-GP7412

Meropenem trihydrate, USP grade

CAS: 119478-56-7

Fórmula: C₁₇H₂₅N₃O₅S·3H₂O

Pureza: ≤ 0.1% (anhydrous basis)

Forma y color: White, off-white or faint beige crystalline powder

Peso molecular: 437.51

Ref: 7W-GP9211

Meropenem trihydrate

CAS: 119478-56-7

Meropenem trihydrate

Pureza: ≥98%

Peso molecular: 437.51g/mol

Ref: 54-BUP15105

Meropenem trihydrate

Producto controlado

CAS: 119478-56-7

Fórmula: C₁₇H₂₅N₃O₅SH₂O

Forma y color: Neat

Peso molecular: 437.51

Ref: 04-C14906000

Meropenem Trihydrate

CAS: 119478-56-7

Forma y color: Neat

Ref: 86-MM1327.00

Meropenem RS

CAS: 119478-56-7

Forma y color: White To Light Yellow Solid Crystalline Powder

Ref: 2K-7000960021

Meropenem Trihydrate

Producto controlado

CAS: 119478-56-7

Applications Meropenem Trihydrate is a carbapenem antibiotic with wide spectrum of antibacterial.
References Hickey, M.B., et al.: J. Pharma. Sci., 96, 1090 (2007); Condie, C.K., et al.: Am. J. Health. System. Pharma., 65, 454 (2008);

Fórmula: C₁₇H₂₅N₃O₅S·3H₂O

Forma y color: Light Yellow

Peso molecular: 437.51

Ref: TR-M225640

Meropenem Trihydrate

CAS: 119478-56-7

Fórmula: C₁₇H₂₅N₃O₅S(H₂O)

Peso molecular: 383.5 : 3(18.0)

Ref: ST-EA-CP-M30000

Meropenem trihydrate

CAS: 119478-56-7

Inhibitor of cell-wall synthesis; carbapenem class

Fórmula: C₁₇H₂₅N₃O₅S·3H₂O

Pureza: Min. 95 Area-%

Forma y color: Powder

Peso molecular: 437.51 g/mol

Ref: 3D-AM16380

Meropenem trihydrate, Antibiotic for Culture Media Use Only

CAS: 119478-56-7

Meropenem trihydrate has broad spectrum activity against Gram-positive and Gram-negative bacteria, as well as, some mycoplasma species. It inhibits cell wall synthesis by binding to bacterial penicillin-binding proteins (PBP), which impairs cell wall integrity, induces the formation of reactive oxygen species, and inhibits macromolecular synthesis in bacteria. It can be used to prevent bacterial growth after being exposed to meropenem through fluorescence imaging of human blood plasma. Meropenem trihydrate research studies showed a reduction of the allergen levels in patients with respiratory allergies or asthma, specifically dust mites, cockroaches, animal dander, pollen grains, etc. by inhibit allergen-induced sensitization of mast cells.

Fórmula: C₁₇H₃₁N₃O₈S

Pureza: Min. 98.0 Area-%

Peso molecular: 437.51 g/mol

Ref: 3D-M-2780

Meropenem trihydrate

CAS: 119478-56-7

Pureza: 97%

Forma y color: Solid

Peso molecular: 437.51

Ref: 10-F792074