CAS 120202-66-6

Sulfato de hidrógeno de clopidogrel

Descripción:

Sulfato de hidrógeno de clopidogrel es un compuesto farmacéutico utilizado principalmente como agente antiplaquetario para prevenir coágulos sanguíneos en pacientes en riesgo de eventos cardiovasculares. Es un profármaco que requiere activación metabólica en el hígado para ejercer sus efectos terapéuticos. La sustancia se caracteriza por su capacidad para inhibir de forma irreversible el receptor P2Y12 en las plaquetas, reduciendo así la agregación plaquetaria. Sulfato de hidrógeno de clopidogrel se administra típicamente por vía oral y es conocido por su relativamente alta biodisponibilidad y larga vida media, lo que permite una dosificación una vez al día. El compuesto es soluble en agua y exhibe estabilidad bajo condiciones normales de almacenamiento, aunque debe protegerse de la luz y la humedad. Los efectos secundarios comunes pueden incluir complicaciones hemorrágicas, trastornos gastrointestinales y reacciones de hipersensibilidad. Debido a su mecanismo de acción, a menudo se prescribe en conjunto con otras terapias antiplaquetarias o anticoagulantes, particularmente en pacientes con antecedentes de infarto de miocardio o accidente cerebrovascular. El monitoreo de la eficacia y los efectos adversos es esencial durante el tratamiento.

Fórmula: C₁₅H₁₆ClNO₆S₂

InChI: InChI=1/C15H14ClNO2S.H2O4S/c16-12-4-2-1-3-11(12)14(15(18)19)17-7-5-13-10(9-17)6-8-20-13;1-5(2,3)4/h1-4,6,8,14H,5,7,9H2,(H,18,19);(H2,1,2,3,4)/t14-;/m0./s1

Clave InChI: InChIKey=FDEODCTUSIWGLK-RSAXXLAASA-N

SMILES: [C@H](C(OC)=O)(N1CC2=C(CC1)SC=C2)C3=C(Cl)C=CC=C3.S(=O)(=O)(O)O

Sinónimos:

• (+)-(S)-5-[(2-Chlorophenyl)(methoxycarbonyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]-pyridin-5-ium hydrogen sulfate]
• (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoic acid sulfate (1:1)
• (S)-(+)-Clopidogrel hydrogen sulfate
• (S)-(+)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate bisulfate
• (S)-(+)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate hydrogen sulfate
• Areplex
• Clopidix
• Clopidogerl Bisulfate
• Clopidogrel Bisulfate
• Clopidogrel Bisulfate I
• Clopidogrel Bisulfate II
• Clopidogrel Bisulfate, FormI/FormII
• Clopidogrel Hydrogen Sulphate
• Clopidogrel Hydrogensulfate
• Clopidogrel Sulphate
• Clopidogrel bisulphate
• Clopidogrel bisulphate Ⅰ/Ⅱ
• Clopidogrel hemisulfate
• Clopidogrel sulfate
• Iscover
• Methyl (+)-(S)-A-(2-Chlorophenyl)-6,7-Dihydrothieno[3,2-C]Pyridine-5(4H)Acetate, Hydrogen Sulfate Salt
• Methyl (S)-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)(2-chlorophenyl)ethanoate hydrogen sulfate
• Myogrel
• Plavitor
• Plavix
• Sr 25990C
• Stroka
• Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (S)-, sulfate (1:1)
• Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (αS)-, sulfate (1:1)
• Trombex
• Zyllt
• Clopidogrel hydrogen sulfate
• (S)-alpha-(2-Chlorophenyl)-6,7-dihydrothieno[3.2-c]pyridine-5(4H)-aceticacidmethylesterhydrogensulfate
• Clopidogrelhydrogenesulfate
• Clopidogrel (Hydrogen)
• (2-Chlorophenyl)-6,7–dihydrothieno[3,2-C]pyridine-5-(4H)-acetic acid methyl ester sulfate
• d-Clopidogrel

(S)-(+)-Clopidogrel Sulfate

CAS: 113665-84-2, 120202-66-6

Fórmula: C₁₆H₁₆ClNO₂S·H₂SO₄

Pureza: >98.0%(HPLC)(N)

Forma y color: White to Almost white powder to crystal

Peso molecular: 419.89

Ref: 3B-C2556

Clopidogrel Hydrogen Sulphate

CAS: 120202-66-6

Forma y color: Neat

Ref: 61-FOR0455.10

Clopidogrel hydrogen sulfate

CAS: 120202-66-6

Clopidogrel hydrogen sulfate

Fórmula: C₁₆H₁₈ClNO₆S₂

Pureza: 99.4%

Forma y color: Off-White

Peso molecular: 419.02641

Ref: 47-1305

CLOPIDOGREL HYDROGEN SULFATE CRS

CAS: 120202-66-6

CLOPIDOGREL HYDROGEN SULFATE CRS

Fórmula: C₁₆H₁₈ClNO₆S₂

Forma y color: White. Whitish. Powder.

Peso molecular: 419.9002

Ref: 41-Y0001333

CLOPIDOGREL FOR SYSTEM SUITABILITY CRS

CAS: 120202-66-6

CLOPIDOGREL FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0001334

Clopidogrel Bisulfate

CAS: 120202-66-6

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Fórmula: C₁₆H₁₆ClNO₂S·H₂SO₄

Forma y color: White Off-White Powder

Peso molecular: 321.05903

Ref: 45-1140430

Thieno[3,2-c]pyridine-5(4H)-acetic acid,a-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (aS)-, sulfate (1:1)

CAS: 120202-66-6

Fórmula: C₁₆H₁₈ClNO₆S₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 419.9002

Ref: IN-DA00ILNY

Clopidogrel hydrogen sulfate

CAS: 120202-66-6

Clopidogrel hydrogen sulfate is a selective P2Y12 receptor blocker that inhibits platelet adhesion and aggregation.

Fórmula: C₁₆H₁₆ClNO₂S·H₂SO₄

Pureza: 99.57% - 99.79%

Forma y color: Solid

Peso molecular: 419.9

Ref: TM-T0182L

Clopidogrel hydrogen sulfate

CAS: 120202-66-6

Clopidogrel hydrogen sulfate

Pureza: ≥98%

Peso molecular: 419.9g/mol

Ref: 54-BUP13803

Clopidogrel Sulfate

CAS: 120202-66-6

Fórmula: C₁₆H₁₆ClNO₂S·H₂SO₄

Forma y color: White To Off-White Solid

Peso molecular: 321.82 98.07

Ref: 4Z-C-131

Clopidogrel Bisulfate

CAS: 120202-66-6

Clopidogrel Bisulfate

Pureza: 99%

Peso molecular: 419.9g/mol

Ref: 54-OR1028933

Clopidogrel Hydrogen Sulphate

CAS: 120202-66-6

Forma y color: Neat

Ref: 86-MM0455.10

(S)-(+)-Clopidogrel hydrogen sulfate

CAS: 120202-66-6

Fórmula: C₁₆H₁₆ClNO₂S·H₂SO₄

Pureza: ≥ 98.0%

Forma y color: White to off-white powder

Peso molecular: 419.90

Ref: 7W-GK4784

Clopidogrel Sulfate RS

CAS: 120202-66-6

Forma y color: White

Ref: 2K-1048900021

S-(+)-Clopidogrel Hydrogen Sulfate

CAS: 120202-66-6

Applications Used as an antithrombotic.
References Mills, D.C.B., et al.: Arterioscler. Thromb., 12, 430 (1992), Feuerstein, G., et al.: Exp. Opin. Invest. Drugs, 4, 425 (1995)

Fórmula: C₁₆H₁₆ClNO₂S·H₂O₄S

Forma y color: Off-White

Peso molecular: 419.90

Ref: TR-C587250

S-(+)-Clopidogrel hydrogen sulfate

CAS: 120202-66-6

Clopidogrel is a potent inhibitor of the platelet aggregation. It reduces blood clotting by inhibiting the ADP receptor on the surface of platelets, thereby inhibiting the aggregation and adhesion of platelets. Clopidogrel has been shown to be effective in preventing thrombosis, myocardial infarction (heart attack), and stroke. Clopidogrel inhibits the activity of cytochrome P450 3A4 (CYP3A4) and p2Y 12 receptors. Clopidogrel has been shown to have synergic effects with nonsteroidal anti-inflammatory drugs (NSAIDs). The polymorphic nature of Clopidogrel can be monitored using a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for quantification in biological samples such as human serum and plasma.

Fórmula: C₁₆H₁₈ClNO₆S₂

Pureza: Min. 98 Area-%

Forma y color: White Powder

Peso molecular: 419.9 g/mol

Ref: 3D-FC20513

S-(+)-Clopidogrel hydrogen sulfate - Bio-X ™

CAS: 120202-66-6

Clopidogrel is a potent inhibitor of the platelet aggregation. It reduces blood clotting by inhibiting the ADP receptor on the surface of platelets, thereby inhibiting the aggregation and adhesion of platelets. Clopidogrel has been shown to be effective in preventing thrombosis, myocardial infarction (heart attack), and stroke. Clopidogrel inhibits the activity of cytochrome P450 3A4 (CYP3A4) and p2Y 12 receptors. Clopidogrel has been shown to have synergic effects with nonsteroidal anti-inflammatory drugs (NSAIDs). The polymorphic nature of Clopidogrel can be monitored using a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for quantification in biological samples such as human serum and plasma.

Fórmula: C₁₆H₁₆ClNO₂S•H₂SO₄

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 419.9 g/mol

Ref: 3D-BC164326