CAS 120202-71-3
:(R)-Clopidogrel bisulfato
Descripción:
(R)-Clopidogrel bisulfato es un medicamento antiplaquetario que se utiliza principalmente para prevenir coágulos sanguíneos en pacientes con enfermedades cardiovasculares. Es un profármaco que requiere activación metabólica para ejercer sus efectos terapéuticos, inhibiendo específicamente el receptor P2Y12 en las plaquetas, evitando así la agregación plaquetaria. El compuesto se caracteriza por su naturaleza quiral, siendo el enantiómero (R) la forma activa responsable de su actividad farmacológica. El bisulfato de clopidogrel se administra típicamente por vía oral y se absorbe bien en el tracto gastrointestinal, aunque su biodisponibilidad se ve afectada por el metabolismo de primer paso. La sustancia a menudo se formula como una sal de bisulfato para mejorar su solubilidad y estabilidad. Los efectos secundarios comunes incluyen complicaciones hemorrágicas, trastornos gastrointestinales y, en casos raros, reacciones de hipersensibilidad. Debido a su mecanismo de acción, es crucial que los pacientes sean monitoreados por signos de sangrado, especialmente cuando se utiliza en conjunto con otros anticoagulantes o agentes antiplaquetarios. En general, (R)-Clopidogrel bisulfato desempeña un papel significativo en el manejo de trastornos trombóticos.
Fórmula:C16H16ClNO2S·H2O4S
InChI:InChI=1S/C16H16ClNO2S.H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14;1-5(2,3)4/h2-5,7,9,15H,6,8,10H2,1H3;(H2,1,2,3,4)/t15-;/m1./s1
Clave InChI:InChIKey=FDEODCTUSIWGLK-XFULWGLBSA-N
SMILES:[C@@H](C(OC)=O)(N1CC2=C(CC1)SC=C2)C3=C(Cl)C=CC=C3.S(=O)(=O)(O)O
Sinónimos:- (R)-(-)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate bisulfate
- (R)-(-)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate hydrogen sulfate
- (R)-Clopidogrel bisulfate
- (R)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate
- Clopidogrel Related Compound C
- Methyl(-)-(R)-(o-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetate, hydrogen sulfate
- Sr 25989C
- Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (αR)-, sulfate (1:1)
- methyl (2R)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoate sulfate
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Encontrado 9 productos.
Clopidogrel Related Compound C (methyl (-)-(R)-(o-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetate, hydrogen sulfate)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C16H16ClNO2S·H2SO4Forma y color:White PowderPeso molecular:321.05903(R)-Methyl 2-(2-chlorophenyl)-2-(4,5-dihydrothieno[2,3-c]pyridin-6(7h)-yl)acetate sulfate
CAS:Fórmula:C16H18ClNO6S2Pureza:97%Forma y color:SolidPeso molecular:419.9002Clopidogrel EP Impurity C Sulfate (Clopidogrel USP Related Compound C, (R)-Clopidogrel Sulfate)
CAS:Fórmula:C16H16ClNO2S·H2SO4Forma y color:White To Off-White SolidPeso molecular:321.82 98.07Clopidogrel Related Compound C
CAS:Clopidogrel Related Compound CPureza:≥95%Peso molecular:419.89g/molClopidogrel Related Compound C
CAS:(R)-Clopidogrel bisulfate (Clopidogrel Related Compound C) is an isomer of clopidogrel. Clopidogrel is a P2Y12 receptor antagonist.Fórmula:C16H18ClNO6S2Pureza:97.84%Forma y color:SolidPeso molecular:419.9R-(-)-Clopidogrel Hydrogen Sulfate
CAS:Producto controlado<p>Impurity Clopidogrel EP Impurity C<br>Stability Very Hygroscopic<br>Applications R-(-)-Clopidogrel Hydrogen Sulfate (Clopidogrel EP Impurity C) is used as an antithrombotic. Clopidogrel Related Compound C<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mills, D.C.B., et al.: Arterioscler. Thromb., 12, 430 (1992), Feuerstein, G., et al.: Exp. Opin. Invest. Drugs, 4, 425 (1995)<br></p>Fórmula:C16H16ClNO2S·H2O4SForma y color:WhitePeso molecular:419.90R-(-)-Clopidogrel hydrogen sulfate
CAS:<p>R-(-)-Clopidogrel hydrogen sulfate is a prodrug of clopidogrel, which is an antiplatelet agent. It is used to prevent thrombotic events in people with coronary artery disease, peripheral arterial disease, or cerebrovascular disease. The drug is broken down in the liver and then converted to an active form by the enzyme CYP2C19. The R-(-)-isomer of clopidogrel has been shown to be more effective for reducing platelet aggregation than its S-enantiomer, with no difference in effectiveness between the two forms for reducing heart attacks and strokes. This drug can be found in wastewater samples due to its use as a therapeutic agent. The method used for analysis was LC-MS/MS and the excipients were not reported.</p>Fórmula:C16H18ClNO6S2Pureza:Min. 98 Area-%Forma y color:White Slightly Yellow PowderPeso molecular:419.02641
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