CAS 120796-97-6
:gran endotelina 38 humana
Descripción:
El big endotelina-1 (a menudo referido como big endotelina-38 en el contexto de la biología humana) es un péptido precursor involucrado en la regulación del tono vascular y la presión arterial. Es parte de la familia de endotelinas, que incluye varios isoformas que son producidas por células endoteliales. La sustancia se caracteriza por su estructura molecular relativamente grande, que se escinde para formar péptidos de endotelina activos, específicamente endotelina-1, -2 y -3. Estos péptidos son potentes vasoconstrictores y juegan un papel crucial en varios procesos fisiológicos, incluyendo la función cardiovascular y el equilibrio de fluidos. El big endotelina-1 se libera típicamente en respuesta a varios estímulos, incluyendo hipoxia e inflamación, y sus niveles pueden ser indicativos de ciertas condiciones patológicas, como la insuficiencia cardíaca y la hipertensión pulmonar. El número CAS 120796-97-6 identifica específicamente este péptido precursor, que es importante para la investigación y aplicaciones clínicas en la comprensión de la salud cardiovascular y los mecanismos de enfermedad.
Fórmula:C189H282N48O56S5
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Encontrado 5 productos.
Big Endothelin-1 (human)
CAS:Human Big ET-1 comprises residues 53-90 of the endothelin precursor (preproendothelin). Compared to the mature endothelin-1 (hET-1), the peptide show less vasoconstrictor activity in vitro, but similar pressor effects in vivo. Former CAS-number 121014-53-7.Fórmula:C189H282N48O56S5Pureza:94.0%Forma y color:White PowderPeso molecular:4282.94Big Endothelin-1 (Human, 1-38)
CAS:<p>This product has disulfide bonds between Cys1-Cys15 and Cys3-Cys11 and is available as a 0.5mg vial. Big Endothelin-1 (Human, 1-38) is a peptide that is a member of the endothelin family and is part of the 39 amino acids of Big Endothelin-1 which is a precursor of Endothelin-1 (ET-1). ET-1 exhibits vasoconstrictive properties and is an activator of endothelin G-protein coupled receptors. Furthermore ET-1 is produced when inflammation, vascular stress or hypoxia occurs. In vivo Big Endothelin-1 has a greater half life compared to ET-1 and therefore makes it useful to study secretory activity in the endothelial system.<br>Overall Big Endothelin-1 (Human, 1-38) can be used as a research tool for studying protein interactions, receptor activation and function, and ligand binding. This peptide is also used in pharmacology to study the effects of therapeutic agents on receptor activity and expression.</p>Fórmula:C189H282N48O56S5Pureza:Min. 95%Peso molecular:4,282.9 g/molBig Endothelin-1 (human)
CAS:<p>Please enquire for more information about Big Endothelin-1 (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Fórmula:C189H282N48O56S5Pureza:Min. 95%Peso molecular:4,282.88 g/molBig Endothelin-1 (Human, 1-38)
CAS:<p>This product has disulfide bonds between Cys1-Cys15 and Cys3-Cys11 and is available as a 0.1mg vial. Big Endothelin-1 (Human, 1-38) is part of the full lengthed 29 amino acid peptide Big Endothlin-1 which is a precursor peptide of the vasoconstrictorEndothelin-1 (ET-1). ET-1 exhibits vasoconstrictive properties and is an activator of endothelin G-protein coupled receptors. Furthermore ET-1 is produced when inflammation, vascular stress or hypoxia occurs. In vivo Big Endothelin-1 has a greater half life compared to ET-1 and therefore makes it useful to study secretory activity in the endothelial system.<br>Overall Big Endothelin-1 (Human, 1-38) can be used as a research tool for studying protein interactions, receptor activation and function, and ligand binding. This peptide is also used in pharmacology to study the effects of therapeutic agents on receptor activity and expression.</p>Fórmula:C189H282N48O56S5Pureza:Min. 95%Peso molecular:4,282.9 g/mol
