CAS 1211877-36-9

(R)-MG132

CAS: 1211877-36-9

Fórmula: C₂₆H₄₁N₃O₅

Pureza: 98%

Forma y color: Solid

Peso molecular: 475.6208

Ref: IN-DA009BMJ

(R)-MG-132

CAS: 1211877-36-9

(R)-MG-132

Pureza: ≥98%

Peso molecular: 475.62g/mol

Ref: 54-BUP12924

(R)-MG-132

CAS: 1211877-36-9

(R)-MG-132 (Z-Leu-D-leu-leu-al) is the enantiomer of MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132.

Fórmula: C₂₆H₄₁N₃O₅

Pureza: 99.90%

Forma y color: Solid

Peso molecular: 475.62

Ref: TM-T12628

(R)-MG-132

Producto controlado

CAS: 1211877-36-9

Fórmula: C₂₆H₄₁N₃O₅

Forma y color: Neat

Peso molecular: 475.621

Ref: TR-M340975

(R)-MG 132

CAS: 1211877-36-9

Ischemia reperfusion injury is a major cause of irreversible brain damage. The enzyme GTPase-activating protein (GAP) has been shown to be involved in the regulation of cell death and may represent a potential therapeutic target for ischemia reperfusion injury. MG132 is an inhibitor of GAP and can protect against brain damage in wild-type mice subjected to cerebral ischemia reperfusion injury. MG132 blocks protein synthesis, leading to apoptotic cell death in cancer cells, while it induces apoptotic cell death in cancer cells. MG132 also inhibits proteasome activity and leads to acute ischemic brain damage in wild-type mice.

Fórmula: C₂₆H₄₁N₃O₅

Pureza: Min. 95%

Peso molecular: 475.63 g/mol

Ref: 3D-LYB87736