CAS 1218-34-4

Acetil-L-triptófano

Descripción:

Acetil-L-triptófano es un derivado del aminoácido triptófano, caracterizado por la adición de un grupo acetilo a su átomo de nitrógeno. Esta modificación mejora su solubilidad y biodisponibilidad en comparación con su compuesto original. La sustancia es típicamente un polvo cristalino blanco a blanco amarillento y es soluble en agua y disolventes orgánicos, lo que la hace útil en diversas aplicaciones bioquímicas. Acetil-L-triptófano es conocido por su posible papel en la síntesis de neurotransmisores, particularmente la serotonina, y puede influir en la regulación del estado de ánimo y el sueño. A menudo se estudia por sus efectos en la función cognitiva y como suplemento dietético. Además, puede exhibir propiedades antioxidantes y se ha investigado por sus posibles aplicaciones terapéuticas en condiciones como la depresión y la ansiedad. Al igual que con muchos derivados de aminoácidos, es importante considerar su perfil de seguridad y dosis cuando se utiliza en suplementos o investigaciones. En general, Acetil-L-triptófano sirve como un compuesto importante en contextos nutricionales y farmacéuticos.

Fórmula: C₁₃H₁₄N₂O₃

InChI: InChI=1S/C13H14N2O3/c1-8(16)15-12(13(17)18)6-9-7-14-11-5-3-2-4-10(9)11/h2-5,7,12,14H,6H2,1H3,(H,15,16)(H,17,18)/t12-/m0/s1

Clave InChI: InChIKey=DZTHIGRZJZPRDV-LBPRGKRZSA-N

SMILES: C([C@H](NC(C)=O)C(O)=O)C=1C=2C(NC1)=CC=CC2

Sinónimos:

• (2S)-2-Acetamido-3-(1H-indol-3-yl)propanoic acid
• (S)-N-Acetyltryptophan
• <span class="text-smallcaps">L</span>-N-Acetyltryptophan
• <span class="text-smallcaps">L</span>-Tryptophan, N-acetyl-
• Ac-L-Trp-OH
• Acetyl-<span class="text-smallcaps">L</span>-tryptophan
• Acetyltryptophan
• N-Acetyl-<span class="text-smallcaps">L</span>-tryptophan
• N-Acetyl-L-Tryptophan
• N-acetyltryptophan
• N-α-Acetyl-L-Tryptophan
• NSC 90726
• Tryptophan, N-acetyl-, <span class="text-smallcaps">L</span>-
• L-Tryptophan, N-acetyl-
• Acetyl-L-tryptophan
• Tryptophan, N-acetyl-, L-

N-Acetyl-L-tryptophan

CAS: 1218-34-4

Fórmula: C₁₃H₁₄N₂O₃

Pureza: >98.0%(HPLC)

Forma y color: White to Light yellow to Light red powder to crystal

Peso molecular: 246.27

Ref: 3B-A0121

N-Acetyl-L-tryptophan, 99%

CAS: 1218-34-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₁₃H₁₄N₂O₃

Pureza: 99%

Forma y color: White to off-white powder

Peso molecular: 246.27

Ref: 02-J64096

Ac-Trp-OH

CAS: 1218-34-4

The NK1 receptor antagonist Ac-Trp (L-NAT) inhibits the secretion of substance P and IL-1β. L-NAT reduced dyskinesia in a hemi-parkinsonian rodent model.

Fórmula: C₁₃H₁₄N₂O₃

Pureza: > 99%

Forma y color: Whitish Powder

Peso molecular: 246.27

Ref: 01-4003876

N-ACETYLTRYPTOPHAN CRS

CAS: 1218-34-4

N-ACETYLTRYPTOPHAN CRS

Fórmula: C₁₃H₁₄N₂O₃

Peso molecular: 246.2619

Ref: 41-A0208000

Tryptophan Related Compound B (2-Acetamido-3-(1H-indol-3-yl)propanoic acid)

CAS: 1218-34-4

Aromatic or modified aromatic heterocyclic compounds withnitrogen hetero-atom(s) only nesoi

Fórmula: C₁₃H₁₄N₂O₃

Forma y color: White Off-White Colorless Crystalline Powder Crystals

Peso molecular: 246.10044

Ref: 45-1700523

L-Tryptophan, N-acetyl-

CAS: 1218-34-4

Fórmula: C₁₃H₁₄N₂O₃

Pureza: 98%

Forma y color: Solid

Peso molecular: 246.2619

Ref: IN-DA001627

N-Acetyl-L-tryptophan, 10mM (in DMSO)

CAS: 1218-34-4

N-Acetyl-L-tryptophan, 10mM (in DMSO)

Pureza: ≥98%

Peso molecular: 246.26g/mol

Ref: 54-BUP19215

N-Acetyl-L-tryptophan

CAS: 1218-34-4

Fórmula: C₁₃H₁₄N₂O₃

Pureza: ≥ 98.5%

Forma y color: White to almost white powder

Peso molecular: 246.30

Ref: 7W-GM7304

N-Acetyltryptophan

Producto controlado

CAS: 1218-34-4

Fórmula: C₁₃H₁₄N₂O₃

Forma y color: Neat

Peso molecular: 246.26

Ref: 86-MM0172.13

N-Acetyl-L-tryptophan

CAS: 1218-34-4

N-Acetyl-L-tryptophan

Pureza: 99%

Forma y color: Solid

Peso molecular: 246.26g/mol

Ref: 54-BIA1792

N-Acetyl-L-tryptophan

CAS: 1218-34-4

N-Acetyl-L-tryptophan (N-acetyltryptophan) is an inhibitor of neurokinin 1 receptor (NK1-receptor, NK1R).

Fórmula: C₁₃H₁₄N₂O₃

Pureza: 99.93%

Forma y color: Solid

Peso molecular: 246.26

Ref: TM-T8789

Tryptophan USP Related Compound B (N-Acetyl-L-Tryptophan)

CAS: 1218-34-4

Fórmula: C₁₃H₁₄N₂O₃

Peso molecular: 246.27

Ref: 4Z-T-2019

N-Acetyl-L-Tryptophan

Producto controlado

CAS: 1218-34-4

Applications N-Acetyl-L-Tryptophan, is a derivative of L-Tryptophan (T947210), that can be used as competitive inhibitor to identify and characterize tryptophanases. It can also be used as an NK1 tachykinin receptor antagonist, that may help to develop a novel therapeutic intervention for the treatment of reperfusion injury in acute ischemic stroke.
References Turner, R. J., et al.: Neuroscience, 220, 1 (2012);

Fórmula: C₁₃H₁₄N₂O₃

Forma y color: White To Off-White

Peso molecular: 246.26

Ref: TR-A168730

N-Acetyl-L-tryptophan

CAS: 1218-34-4

N-Acetyl-L-tryptophan is a neuroprotective agent that binds to the group p2 receptor for neurokinin-1 (NK-1) and inhibits the apoptosis pathway. It is used in the treatment of Parkinson's disease, Alzheimer's disease, and Huntington's disease. N-Acetyl-L-tryptophan has been shown to inhibit inflammatory lesions in rats with experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis. This drug also interacts with toll-like receptor 4 (TLR4), which activates downstream signaling cascades involving NFκB, MAP kinase, and JAK/STAT pathways. The molecular docking analysis revealed that N-acetyl tryptophan binds to specific sites on TLR4 and prevents its activation by preventing binding of LPS.

Fórmula: C₁₃H₁₄N₂O₃

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 246.26 g/mol

Ref: 3D-FA37435

N-Acetyl-L-Tryptophan extrapure, 99%

CAS: 1218-34-4

Fórmula: C₁₃H₁₄N₂O₃

Pureza: min. 99%

Forma y color: Off - white to pale brown, Powder, Clear

Peso molecular: 246.3

Ref: SR-11644

N-Acetyl-L-Tryptophan ExiPlus, Multi-Compendial, 99%

CAS: 1218-34-4

Fórmula: C₁₃H₁₄N₂O₃

Pureza: min. 99%

Forma y color: Off white to pale brown, Powder, Clear

Peso molecular: 246.3

Ref: SR-48861

Ac-Trp-OH

CAS: 1218-34-4

M03025 - Ac-Trp-OH

Fórmula: C₁₃H₁₄N₂O₃

Pureza: 98%

Forma y color: Solid

Peso molecular: 246.266

Ref: 10-M03025

Tryptophan USP Related Compound B

CAS: 1218-34-4

Fórmula: C₁₃H₁₄N₂O₃

Peso molecular: 246.27

Ref: ST-EA-CP-T90020