CAS 121808-62-6

Pidotimod

Descripción:

Pidotimod es un agente inmunomodulador sintético utilizado principalmente en el tratamiento de infecciones respiratorias recurrentes, particularmente en niños. Se caracteriza por su capacidad para mejorar la respuesta inmune, especialmente al estimular la actividad de los linfocitos T y promover la producción de citoquinas. Pidotimod es conocido por su baja toxicidad y perfil de seguridad favorable, lo que lo hace adecuado para su uso a largo plazo. La sustancia se administra típicamente por vía oral y se absorbe bien en el tracto gastrointestinal. Su mecanismo de acción implica la modulación tanto de la inmunidad innata como de la adaptativa, lo que ayuda a mejorar la defensa del cuerpo contra patógenos. Pidotimod también ha sido estudiado por sus posibles beneficios en diversas condiciones alérgicas y autoinmunitarias. Como entidad química, se clasifica como una pequeña molécula con una estructura molecular específica que contribuye a su actividad biológica. En general, Pidotimod representa una opción terapéutica valiosa para mejorar la función inmune y reducir la frecuencia de infecciones.

Fórmula: C₉H₁₂N₂O₄S

InChI: InChI=1S/C9H12N2O4S/c12-7-2-1-5(10-7)8(13)11-4-16-3-6(11)9(14)15/h5-6H,1-4H2,(H,10,12)(H,14,15)/t5-,6-/m0/s1

Clave InChI: InChIKey=UUTKICFRNVKFRG-WDSKDSINSA-N

SMILES: C(=O)(N1[C@H](C(O)=O)CSC1)[C@H]2NC(=O)CC2

Sinónimos:

• (4R)-3-[[(2S)-5-Oxo-2-pyrrolidinyl]carbonyl]-4-Thiazolidinecarboxylic acid
• 4-Thiazolidinecarboxylic acid, 3-[(5-oxo-2-pyrrolidinyl)carbonyl]-, [R-(R*,S*)]-
• 4-Thiazolidinecarboxylic acid, 3-[[(2S)-5-oxo-2-pyrrolidinyl]carbonyl]-, (4R)-
• Adimod
• Axil (pharmaceutical)
• Onaka
• Pidotimond
• Pigitil
• Polimod
• Pidotimod

(4R)-3-{[(2S)-5-oxopyrrolidin-2-yl]carbonyl}-1,3-thiazolidine-4-carboxylic acid

CAS: 121808-62-6

Fórmula: C₉H₁₂N₂O₄S

Pureza: 98%

Forma y color: Solid

Peso molecular: 244.2676

Ref: IN-DA00162L

Pidotimod

CAS: 121808-62-6

Pidotimod is a synthetic dipeptide with immunomodulatory properties.

Fórmula: C₉H₁₂N₂O₄S

Pureza: 97.56% - 99.74%

Forma y color: Almost White To White Crystalline Powder

Peso molecular: 244.27

Ref: TM-T1532

Pidotimod

CAS: 121808-62-6

Pidotimod

Pureza: ≥95%

Peso molecular: 244.27g/mol

Ref: 54-BUP16766

Pidotimod

CAS: 121808-62-6

Fórmula: C₉H₁₂N₂O₄S

Forma y color: White To Off-White Solid

Peso molecular: 244.27

Ref: 4Z-P-136001

(R)-3-((S)-5-Oxopyrrolidine-2-Carbonyl)Thiazolidine-4-Carboxylic Acid

CAS: 121808-62-6

(R)-3-((S)-5-Oxopyrrolidine-2-Carbonyl)Thiazolidine-4-Carboxylic Acid

Pureza: 98%

Peso molecular: 244.27g/mol

Ref: 54-OR1008478

Pidotimod

CAS: 121808-62-6

Fórmula: C₉H₁₂N₂O₄S

Peso molecular: 244.27

Ref: 7W-GP9654

Pidotimod

CAS: 121808-62-6

Fórmula: C₉H₁₂N₂O₄S

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 244.27

Ref: 3B-P2147

Pidotimod

Producto controlado

CAS: 121808-62-6

Applications Immunostimulant used in patients with cell-mediated immunodepression.
References Gu, C., et al.: Pharm. Res., 25, 979 (2008), Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Giagulli, C., et al.: Int. Immunopharmacol., 9, 1366 (2009),

Fórmula: C₉H₁₂N₂O₄S

Forma y color: Neat

Peso molecular: 244.27

Ref: TR-P437650

Pidotimod

CAS: 121808-62-6

Pidotimod is a small molecule (dipeptide) that acts as immunomodulator. It activates the immune system by binding to Toll-like receptor (TLR) 4 and TLR2 and it is involved in the regulation of TLRs signaling pathways. Pidotimod has chemokine activity on CXC chemokine receptor 3 (CXCR3) that triggers monocyte adhesion and migration by activation of tyrosine phosphorylation-based cell signaling. Recent studies showed that pidotimod can be used to treat acute respiratory tract infections (RTIs) and its pharmacokinetic studies has shown its ability to boost the immunoresponse and favouring the increase in the level of immunoglobulins (IgA, IgM, IgG) and T-lymphocytes (CD3+, CD4+). Pidotimod also exhibits anti-inflammatory properties by inhibiting the production of pro-inflammatory molecules such as IL-6 and TNF-α, which are linked to autoimmune diseases

Fórmula: C₉H₁₂N₂O₄S

Pureza: Min 98%

Forma y color: White Powder

Peso molecular: 244.27 g/mol

Ref: 3D-FP27040

Pidotimod - Bio-X ™

CAS: 121808-62-6

Pidotimod is a small molecule (dipeptide) that acts as immunomodulator. It activates the immune system by binding to Toll-like receptor (TLR) 4 and TLR2 and it is involved in the regulation of TLRs signaling pathways. Pidotimod has chemokine activity on CXC chemokine receptor 3 (CXCR3) that triggers monocyte adhesion and migration by activation of tyrosine phosphorylation-based cell signaling. Recent studies showed that pidotimod can be used to treat acute respiratory tract infections (RTIs) and its pharmacokinetic studies has shown its ability to boost the immunoresponse and favouring the increase in the level of immunoglobulins (IgA, IgM, IgG) and T-lymphocytes (CD3+, CD4+). Pidotimod also exhibits anti-inflammatory properties by inhibiting the production of pro-inflammatory molecules such as IL-6 and TNF-α, which are linked to autoimmune diseases.

Fórmula: C₉H₁₂N₂O₄S

Forma y color: Powder

Peso molecular: 244.27 g/mol

Ref: 3D-BP164260

(R)-3-((S)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid

CAS: 121808-62-6

Fórmula: C₉H₁₂N₂O₄S

Pureza: 98%

Forma y color: Solid

Peso molecular: 244.27

Ref: 10-F211857