CAS 1222-05-5

Galaxolide

Descripción:

Galaxolide, con el número CAS 1222-05-5, es un compuesto de almizcle sintético ampliamente utilizado en la industria de fragancias. Se caracteriza por su agradable olor a almizcle, que se asemeja al del almizcle natural. Galaxolide es un líquido incoloro a amarillo pálido a temperatura ambiente y es conocido por su estabilidad y baja volatilidad, lo que lo hace adecuado para su uso en varios productos de cuidado personal, detergentes y artículos del hogar. El compuesto es lipofílico, lo que le permite mezclarse bien con aceites y grasas, mejorando su efectividad como fijador de fragancias. Galaxolide se considera generalmente seguro para su uso en cosméticos, aunque su impacto ambiental ha suscitado preocupaciones debido a su persistencia en entornos acuáticos. Se clasifica como un almizcle policíclico, que se refiere a un grupo de almizcles sintéticos que pueden acumularse en el medio ambiente. En general, el perfil de aroma deseable y la estabilidad de Galaxolide contribuyen a su popularidad en formulaciones de fragancias, mientras que la investigación continua evalúa sus efectos ecológicos.

Fórmula: C₁₈H₂₆O

InChI: InChI=1S/C18H26O/c1-11-9-19-10-13-7-15-16(8-14(11)13)18(5,6)12(2)17(15,3)4/h7-8,11-12H,9-10H2,1-6H3

Clave InChI: InChIKey=ONKNPOPIGWHAQC-UHFFFAOYSA-N

SMILES: CC1(C)C=2C(=CC3=C(C2)COCC3C)C(C)(C)C1C

Sinónimos:

• 1,3,4,6,7,8-HEXAHYDRO-4,6,6,7,8,8- HEXAMETHYL CYCLOPENTA-γ-2-BENZOPYRAN
• 1,3,4,6,7,8-Hexahidro-4,6,6,7,8,8-Hexametilindeno[5,6-C]Pirano
• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-Hexamethylindeno(5,6-C)Pyr
• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-Hexamethylindeno[5,6-C]Pyranne
• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethyl-cyclopenta-gamma-2-benzopyran
• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclo-penta[g]-2-benzo pyrane
• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran
• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyrane
• 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylindeno[5,6-c]pyrane
• 1,3,4,6,7,8-Hexahydro-4,6,6,8,8,8-hexamethylcyclopenta-2-benzopyran
• 1-[2-(Dimethylamino)-1-(4-Methoxyphenyl)Ethyl]Cyclohexanol Hydrochloride (1:1)
• 4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-Hexahydrocyclopenta[G]Isochromene
• Abbalide
• Cimalide 50
• Cyclopenta[g]-2-benzopyran, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-
• Galaxolide
• Galaxolide 50
• Galaxolide 50BB
• Galaxolide 50IPM
• Galaxolide Abbalide
• Galaxolide White
• Hhcb
• Pearlide
• Venlafaxine

1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran (ca. 50% in Diethyl Phthalate)

CAS: 1222-05-5

Fórmula: C₁₈H₂₆O

Forma y color: Colorless to Light yellow clear liquid

Peso molecular: 258.41

Ref: 3B-G0415

Cyclopenta[g]-2-benzopyran, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-

CAS: 1222-05-5

Fórmula: C₁₈H₂₆O

Pureza: 70%

Forma y color: Liquid

Peso molecular: 258.3984

Ref: IN-DA0016XN

Galaxolide

CAS: 1222-05-5

Ref: 7W-GK3703

4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-Hexahydrocyclopenta[G]Isochromene

CAS: 1222-05-5

4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-Hexahydrocyclopenta[G]Isochromene

Pureza: 70%

Peso molecular: 258.40g/mol

Ref: 54-OR1011338

Mix 1 of Musk a. Polycy. Musk Comp. 10 µg/mL in Cyclohexane

CAS: 105-95-3, 1222-05-5, 13171-00-1, 15323-35-0, 21145-77-7, 33704-61-9, 68140-48-7, 81-14-1, 81-15-2, 83-66-9

Fórmula: C₁₄H₂₂O

Forma y color: Mixture

Peso molecular: 206.32

Ref: 04-LA19020100CY

HHCB

CAS: 1222-05-5

Fórmula: C₁₈H₂₆O

Forma y color: Colourless

Peso molecular: 258.40

Ref: 04-C14213000

HHCB 10 µg/mL in Isooctane

Producto controlado

CAS: 1222-05-5

Fórmula: C₁₈H₂₆O

Forma y color: Single Solution

Peso molecular: 258.40

Ref: 04-A14213000IO-10

Galaxolide-13C-d2

CAS: 1222-05-5

Fórmula: CC₁₇H₂₄D₂O

Peso molecular: 261.41

Ref: 4Z-G-159002

Galaxolide

CAS: 1222-05-5

Fórmula: C₁₈H₂₆O

Peso molecular: 258.41

Ref: 4Z-G-159001

Galaxolide (Mixture of Diastereomers)

Producto controlado

CAS: 1222-05-5

Stability Moisture sensitive
Applications Galaxolide is a polycyclic musk (PCM) used as a fragrance ingredient in perfumes, soaps, cosmetics and detergents. It is increasingly found in the Great Lakes. An assessment by Green-Screen for Safer Chemicals indicates that it is toxic to aquatic life.This compound is a contaminant of emerging concern (CECs).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mori, T. et al.: J. Health Sci., 52, 276 (2006); Chen Y., et al.: Flav. Frag. J., 21, 822 (2006); Chem. and Eng. News, May 2 (2016), page 19

Fórmula: C₁₈H₂₆O

Pureza: >80%

Forma y color: Colourless

Peso molecular: 258.4

Ref: TR-G189000

Galaxolide-d6 (Mixture of Diastereomers) (>80%)

Producto controlado

CAS: 1222-05-5

Applications Galaxolide-d6 is the isotope labelled analog of Galaxolide (G189000); a polycyclic musk (PCM) used as a fragrance ingredient in perfumes, soaps, cosmetics and detergents.
References Mori, T. et al.: J. Health Sci., 52, 276 (2006); Chen Y. et al.: Flav. Frag. J., 21, 822 (2006)

Fórmula: C₁₈H₂₀D₆O

Pureza: >80%

Forma y color: Neat

Peso molecular: 264.43541

Ref: TR-G189002

Galaxolide - Mixture of Diastereomers

CAS: 1222-05-5

Galaxolide is a mixture of diastereomers that has been shown to inhibit the growth of bacteria in wastewater treatment systems. It also has high resistance to oxidation and biological attack, which makes it an ideal candidate for use as an antimicrobial agent. Galaxolide exhibits strong inhibitory properties against bacterial membrane potentials and mitochondrial membrane potential, and displays antioxidant activity in vitro. The molecular docking analysis of galaxolide showed that it binds to the active site of triclosan-induced peroxidase. This binding inhibits the enzyme activity of this enzyme, which is responsible for oxidative injury in cells. The chemical structures of galaxolide have been determined using a variety of analytical methods, including dispersive solid-phase extraction with fluorescence detection.

Fórmula: C₁₈H₂₆O

Pureza: Min. 95%

Forma y color: Yellow Powder

Peso molecular: 258.4 g/mol

Ref: 3D-FG23642

Galaxolide-13C3 (Mixture of Diastereomers)

Producto controlado

CAS: 1222-05-5

Fórmula: C₃C₁₅H₂₆O

Forma y color: Neat

Peso molecular: 261.38

Ref: TR-G189003

Galaxolide (solution 50% in diethyl phthalate)

Producto controlado

CAS: 1222-05-5

Applications Galaxolide is a polycyclic musk (PCM) used as a fragrance ingredient in perfumes, soaps, cosmetics and detergents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mori, T. et al.: J. Health Sci., 52, 276 (2006); Chen Y. et al.: Flav. Frag. J., 21, 822 (2006);

Fórmula: C₁₈H₂₆O

Forma y color: Single Solution

Peso molecular: 258.4

Ref: TR-G189001

Galaxolide solution, 50% in diethyl phthalate

CAS: 1222-05-5

Galaxolide is a synthetic fragrance ingredient. It is a mixture of two isomers, alpha- and beta-galaxolide. Galaxolide has been shown to have antimicrobial properties and can be used in the treatment of wastewater. The analytical method for galaxolide includes dispersive solid phase extraction with benzalkonium chloride (BAC). The BAC forms an ionic complex with galaxolide that can then be extracted into organic solvent. Galaxolide also has high resistance to microbial degradation and can be used as an antimicrobial agent in cosmetics.

Fórmula: C₁₈H₂₆O

Pureza: Min. 95%

Forma y color: Clear Liquid

Peso molecular: 258.4 g/mol

Ref: 3D-FG45940

Galaxolide

CAS: 1222-05-5

Galaxolide can induce estrogenic activity (Estrogen Receptor/ERR), oxidative stress, and genotoxicity. It also stimulates the enzymatic activities of EROD and GST (Glutathione S-transferase).

Fórmula: C₁₈H₂₆O

Forma y color: Solid

Peso molecular: 258.40

Ref: TM-T201465