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CAS 123155-04-4

:

2,3-Di-O-metil-6-O-terc-butil-dimetilsilil β-ciclodextrina

Descripción:
2,3-Di-O-metil-6-O-terc-butil-dimetilsilil β-ciclodextrina es un derivado modificado de β-ciclodextrina, un oligosacárido cíclico compuesto por siete unidades de glucosa. Este compuesto presenta grupos funcionales específicos que mejoran su solubilidad y estabilidad, haciéndolo útil en diversas aplicaciones, particularmente en la entrega y formulación de medicamentos. La presencia de dos grupos metoxi en las posiciones 2 y 3 y un grupo tert-butildimetilsililo en la posición 6 altera significativamente sus propiedades químicas, permitiendo una mejor interacción con moléculas hidrofóbicas. Esta modificación aumenta la lipofilia de la ciclodextrina, facilitando la encapsulación de medicamentos poco solubles. Además, el voluminoso grupo sililo proporciona protección estérica, lo que puede mejorar la estabilidad del compuesto bajo diversas condiciones. La estructura única de este compuesto le permite formar complejos de inclusión, lo que lo hace valioso en aplicaciones farmacéuticas, como mejorar la biodisponibilidad de ingredientes farmacéuticos activos. En general, 2,3-Di-O-metil-6-O-terc-butil-dimetilsilil β-ciclodextrina se caracteriza por su solubilidad modificada, estabilidad y capacidad para formar complejos con diversas moléculas huésped.
Fórmula:C98H196O35Si7
InChI:InChI=1S/C98H196O35Si7/c1-92(2,3)134(36,37)113-50-57-64-71(99-22)78(106-29)85(120-57)128-65-58(51-114-135(38,39)93(4,5)6)122-87(80(108-31)72(65)100-23)130-67-60(53-116-137(42,43)95(10,11)12)124-89(82(110-33)74(67)102-25)132-69-62(55-118-139(46,47)97(16,17)18)126-91(84(112-35)76(69)104-27)133-70-63(56-119-140(48,49)98(19,20)21)125-90(83(111-34)77(70)105-28)131-68-61(54-117-138(44,45)96(13,14)15)123-88(81(109-32)75(68)103-26)129-66-59(52-115-136(40,41)94(7,8)9)121-86(127-64)79(107-30)73(66)101-24/h57-91H,50-56H2,1-49H3/t57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71+,72+,73+,74+,75+,76+,77+,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-/m1/s1
Clave InChI:InChIKey=YJLSGORJJHKFEN-CUVGCOKVSA-N
SMILES:C(O[Si](C(C)(C)C)(C)C)[C@@H]1[C@@]2([C@H](OC)[C@@H](OC)[C@](O1)(O[C@@]3([C@@H](CO[Si](C(C)(C)C)(C)C)O[C@@]([C@H](OC)[C@H]3OC)(O[C@@]4([C@@H](CO[Si](C(C)(C)C)(C)C)O[C@@]([C@H](OC)[C@H]4OC)(O[C@@]5([C@@H](CO[Si](C(C)(C)C)(C)C)O[C@](O[C@]6([C@H](OC)[C@@H](OC)[C@@](O[C@]7([C@H](OC)[C@@H](OC)[C@@](O[C@]8([C@H](OC)[C@@H](OC)[C@@](O2)(O[C@@H]8CO[Si](C(C)(C)C)(C)C)[H])[H])(O[C@@H]7CO[Si](C(C)(C)C)(C)C)[H])[H])(O[C@@H]6CO[Si](C(C)(C)C)(C)C)[H])[H])([C@H](OC)[C@H]5OC)[H])[H])[H])[H])[H])[H])[H])[H]
Sinónimos:
  • β-Cyclodextrin, 6A,6B,6C,6D,6E,6F,6G-heptakis-O-[(1,1-dimethylethyl)dimethylsilyl]-2A,2B,2C,2D,2E,2F,2G,3A,3B,3C,3D,3E,3F,3G-tetradeca-O-methyl-
  • 6A,6B,6C,6D,6E,6F,6G-Heptakis-O-[(1,1-dimethylethyl)dimethylsilyl]-2A,2B,2C,2D,2E,2F,2G,3A,3B,3C,3D,3E,3F,3G-tetradeca-O-methyl-β-cyclodextrin
  • Heptakis(6-O-tert-butyldimethylsilyl-2,3-di-O-methyl)-β-cyclodextrin
  • 2,4,7,9,12,14,17,19,22,24,27,29,32,34-Tetradecaoxaoctacyclo[31.2.2.23,6.28,11.213,16.218,21.223,26.228,31]nonatetracontane, β-cyclodextrin deriv.
  • 2,3-Di-O-methyl-6-O-tert-butyldimethylsilyl β-cyclodextrin
  • Heptakis(2,3-di-O-Methyl-6-O-tert-butyldiMethylsilyl)cycloMaltoheptaose.
  • Heptakis(2,3-di-O-Methyl-6-O-tert-butyldiMethylsilyl)-β-cyclodextrin
  • 2,3-Dimethyl-6-tert-butyldimethylsilyl-b-cyclodextrin
Ordenar por
Pureza (%)
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Encontrado 3 productos.
  • Heptakis(2,3-di-O-methyl-6-O-tert-butyldimethylsilyl)-b-cyclodextrin
    Glentham
    + Info

    Heptakis(2,3-di-O-methyl-6-O-tert-butyldimethylsilyl)-b-cyclodextrin

    CAS:

    Ref: 7W-GC4427

    ne
    A consultar
  • Heptakis(2,3-di-O-methyl-6-O-tert-butyldimethylsilyl)-β-cyclodextrin
    TRC
    + Info

    Heptakis(2,3-di-O-methyl-6-O-tert-butyldimethylsilyl)-β-cyclodextrin

    Producto controlado
    CAS:
    <p>Applications A β-Cyclodextrin derivative.<br>References Yan, D., et al.: Science, 303, 65 (2004), Gou, P.-F., et al.: Biomacromolecules, 11, 934 (2010),<br></p>
    Fórmula:C98H196O35Si7
    Forma y color:White
    Peso molecular:2131.18

    Ref: TR-H281105

    50mg
    170,00€
    100mg
    273,00€
    250mg
    620,00€
  • 2,3-Dimethyl-6-tert-butyldimethylsilyl-b-cyclodextrin
    Biosynth
    + Info

    2,3-Dimethyl-6-tert-butyldimethylsilyl-b-cyclodextrin

    CAS:
    <p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>
    Fórmula:C98H196O35Si7
    Pureza:Min. 95 Area-%
    Forma y color:White Off-White Powder
    Peso molecular:2,131.18 g/mol

    Ref: 3D-OH16463

    1g
    1.995,00€
    50mg
    253,00€
    100mg
    430,00€
    250mg
    699,00€
    500mg
    1.131,00€