CAS 125-71-3

Dextrometorfano

Descripción:

Dextrometorfano (DXM) es un derivado sintético de morfinano que se utiliza principalmente como supresor de la tos en medicamentos de venta libre. Se clasifica como un agente antitusígeno no opioide, lo que significa que alivia la tos sin las propiedades adictivas asociadas con los opioides. El DXM actúa sobre el sistema nervioso central, dirigiéndose específicamente al receptor sigma-1 y al receptor NMDA, lo que contribuye a sus efectos supresores de la tos. La sustancia se administra típicamente en varias formulaciones, incluyendo jarabes, tabletas y pastillas. Dextrometorfano generalmente es bien tolerado, pero puede causar efectos secundarios como mareos, náuseas y somnolencia. A dosis más altas, puede producir efectos disociativos similares a los de los alucinógenos, lo que lleva a su potencial de abuso. La estructura química del DXM incluye un grupo metoxi, que lo distingue de otros morfinanos. Su número CAS, 125-71-3, es un identificador único utilizado para fines regulatorios y de seguridad. En general, aunque el DXM es efectivo para tratar la tos, debe usarse de manera responsable para evitar efectos adversos y potencial abuso.

Fórmula: C₁₈H₂₅NO

InChI: InChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17+,18+/m1/s1

Clave InChI: InChIKey=MKXZASYAUGDDCJ-NJAFHUGGSA-N

SMILES: O(C)C=1C=C2[C@]34[C@@]([C@](CC2=CC1)(N(C)CC3)[H])(CCCC4)[H]

Sinónimos:

• (+)-3-Methoxy-17-methylmorphinan
• (+)-3-methoxy-N-methylmorphinan
• (+)-cis-1,3,4,9,10,10a-hexahydro-6-methoxy-11-methyl-2H-10,4a-iminoethanophenanthrene
• (14Α)-3-Methoxy-17-Methylmorphinan
• (9α,13α,14α)-3-Methoxy-17-methylmorphinan
• 3-Methoxy-17-Methyl-(9Alpha,13Alpha,14Alpha)-Morphinan
• 3-Methoxy-17-methyl-9α,13α,14α-morphinan
• 9α,13α,14α-Morphinan, 3-methoxy-17-methyl-
• Ba 2666
• Benylin DM
• D-1,2,3,9,10,10a-Hexahydro-6-methoxy-11-methyl-4H-10,4a-iminoethanophenanthrene
• D-3-Methoxy-N-methylmorphinan
• DEX
• DXM
• DXM Free Base
• Dextromethorphane
• Dextrometorfano
• Morphinan, 3-methoxy-17-methyl-, (9α,13α,14α)-
• Nodex
• Romilar CF
• d-Methorphan

Dextromethorphan

CAS: 125-71-3

Drugs containing a quinoline or isoquinoline ring-system (whether or not hydrogenated) not further fused

Fórmula: C₁₈H₂₅NO

Forma y color: White Light Yellow Powder

Peso molecular: 271.19361

Ref: 45-1180503

Dextromethorphan, 1mg/ml in Methanol

CAS: 125-71-3

Forma y color: Single Solution

Ref: LP-DEX-873-FB-1LM

Dextromethorphan

CAS: 125-71-3

Forma y color: Neat

Ref: LP-DEX-873-FB

N-Nitroso Dextromethorphan

Producto controlado

CAS: 125-71-3

Applications N-Nitroso Dextromethorphan is an impurity of Dextromethorphan (D299445). Dextromethorphan is an antitussive compound showing analgesic properties. Used in cough medication formulations.
References Church J. et al.: Can J Physiol Pharmacol., 67, 561 (1989); Carliss, R. et al.: Neurotoxicology., 28, 813 (2007);

Fórmula: C₁₇H₂₂N₂O₂

Forma y color: Neat

Peso molecular: 286.369

Ref: TR-N839350

Dextromethorphan

CAS: 125-71-3

Applications Dextromethorphan is an antitussive compound showing analgesic properties. Used in cough medication formulations.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Church J. et al.: Can J Physiol Pharmacol., 67, 561 (1989); Carliss, R. et al.: Neurotoxicology., 28, 813 (2007);

Fórmula: C₁₈H₂₅NO

Forma y color: Neat

Peso molecular: 271.40

Ref: TR-D299445

Dextromethorphan

Producto controlado

CAS: 125-71-3

9-alpha,-14-alpha-3-Methoxy-17-methylmorphinan (914) is a drug that is used in the treatment of bowel disease. It has been shown to inhibit the activity of enzymes such as polymerase chain, which is responsible for DNA replication and repair. 914 also inhibits dextromethorphan, an opioid that is used in cough suppressant medications. The effects of 914 on dextromethorphan are seen in human subjects who have been given the drug intravenously or orally. 914 binds to receptors that are found on cells in the brain and spinal cord, which explains its analgesic properties. This drug can be dangerous when taken with nonsteroidal anti-inflammatory drugs because it can cause kidney damage or failure.

Fórmula: C₁₈H₂₅NO

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 271.4 g/mol

Ref: 3D-FM36326