
CAS 1256585-15-5
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Alectinib-d8
CAS:Producto controladoApplications Alectinib-d8 is the labelled analogue of Alectinib (C183365, HCl), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth. Also is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth.
References Sakamoto, H., et al.: Cancer Cell., 19, 679 (2011); Kinoshita, K., et al.: Bio-org. Medn., 20, 1271 (2012);Fórmula:C30D8H26N4O2Forma y color:NeatPeso molecular:490.66
