CAS 1259314-65-2

JP1302 dihydrochloride

CAS: 1259314-65-2

JP1302 dihydrochloride: selective α2C-adrenoceptor antagonist; Ki=28 nM, Kb=16 nM.

Fórmula: C₂₄H₂₆Cl₂N₄

Pureza: 99.61%

Forma y color: Solid

Peso molecular: 441.4

Ref: TM-T11726

JP1302 dihydrochloride

CAS: 1259314-65-2

JP1302 dihydrochloride

Pureza: ≥95%

Peso molecular: 441.4g/mol

Ref: 54-BUP12888

JP 1302 Dihydrochloride

Producto controlado

CAS: 1259314-65-2

Applications JP 1302 Dihydrochloride is an α2-adrenoceptor blocker and can be used for the treatment or prevention of nephropathy.
References Tsutsui, H.; Yukimura, T.: PCT Int. Appl. 23pp. Patent 2013 CODEN:PIXXD2

Fórmula: C₂₄H₂₄N₄·2(HCl)

Forma y color: Neat

Peso molecular: 441.39

Ref: TR-J212010

JP 1302 dihydrochloride

CAS: 1259314-65-2

JP 1302 dihydrochloride is a potential research tool for studying the pharmacology of synaptic transmission. It was shown to have dose-dependent effects on neurotransmitter release in vitro. JP 1302 dihydrochloride has been shown to increase noradrenaline release from nerve endings in rat brain slices, with a maximum effect at 10 μM. This effect was mediated by stimulation of adrenergic receptors, as demonstrated by the dose-dependent inhibition of this effect observed by rauwolscine, an antagonist of these receptors. JP 1302 dihydrochloride also increases the frequency of nerve impulses in rats and may be useful in the study of monosynaptic transmission.

Fórmula: C₂₄H₂₄N₄·2HCl

Pureza: Min. 95%

Peso molecular: 441.4 g/mol

Ref: 3D-JAC31465