CAS 125971-94-0

1,1-Dimetiletil (4R,6R)-6-(cianometil)-2,2-dimetil-1,3-dioxano-4-acetato

Descripción:

1,1-Dimetiletil (4R,6R)-6-(cianometil)-2,2-dimetil-1,3-dioxano-4-acetato, con el número CAS 125971-94-0, es un compuesto químico caracterizado por su estructura compleja, que incluye un anillo de dioxano y varios grupos funcionales como un grupo cianometilo y un moiety de acetato. Este compuesto probablemente exhiba propiedades típicas de los derivados de dioxano, incluyendo una posible solubilidad en disolventes orgánicos y estabilidad bajo ciertas condiciones. La presencia del grupo cianometilo sugiere una reactividad potencial, particularmente en reacciones de adición nucleofílica. La estereoquímica indicada por la configuración (4R,6R) puede influir en su actividad biológica e interacciones con otras moléculas. Al igual que muchos compuestos orgánicos, sus propiedades físicas como el punto de ebullición, el punto de fusión y la densidad dependerían de las interacciones moleculares específicas y la presencia de grupos funcionales. Se deben consultar los datos de seguridad y las precauciones de manejo, ya que los compuestos con funcionalidades de cianuro pueden presentar riesgos de toxicidad. En general, este compuesto puede tener aplicaciones en síntesis orgánica o como un intermedio en el desarrollo farmacéutico.

Fórmula: C₁₄H₂₃NO₄

InChI: InChI=1/C14H23NO4/c1-13(2,3)19-12(16)9-11-8-10(6-7-15)17-14(4,5)18-11/h10-11H,6,8-9H2,1-5H3/t10-,11-/m1/s1

Clave InChI: InChIKey=DPNRMEJBKMQHMC-GHMZBOCLSA-N

SMILES: C(C(OC(C)(C)C)=O)[C@@H]1OC(C)(C)O[C@H](CC#N)C1

Sinónimos:

• ((4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-[1,3]dioxan-4-yl)acetic acid tert-butyl ester
• (4R,3R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
• (4R,6R)-Tert-Butyl-6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetate
• (4R,6R)-t-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
• (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate (ATS-8)
• (4R,Cis)-1,1-dimethylethyl-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
• (4R-cis)-1,1-Dimethylethyl-6-Cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
• (4R-cis)-1,1-Dimethylethyl-6-Cyanomethyl-2,2-dlmethyl-1,3-dioxane-4-acetate
• (6R-Cyanomethyl-2,2-dimethyl-[1,3]dioxan-4R-yl)acetic acid tert-butyl ester
• 1,1-Dimethylethyl (4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
• 1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6R)-
• 1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R-cis)-
• ATS-8(for Atorvastatin)
• Ast-8
• Atorvastatin Calcium Intermediate ATS-8
• AtorvastatinCalcium(ATS-8)
• Ats-8
• Tert-Butyl (4R,3R)-6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetate
• Tert-Butyl 2-((4R,6R)-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl) acetate
• tert-Butyl(3R,5R)-6-cyano-3,5-O-iso-propylidene-3,5-dihydroxyhexanoate
• tert-butyl [(4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate
• (4R,CIS)-1,1-DIMETHYLETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE(ATS-8)
• Intermediateofatorvastatinecalcium(CAS#134523-03-8)
• (4R,6R)-Tert-Butyl-6-Cyanometh
• 1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-1,1-dimethylethylester
• Ats-8:(4R,Cis)-1,1-Dimethylethyl-Cyanomethyl-2,2-Dimethyl
• ATS-8:(4R-CIS)-T-ETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,2-DIMETHYL-1,2-DIONMANO 1 ACETATE
• (4R-Cis)-1,1-dimethylethyl-6-cyanomethyl-2,2-dimethyl-1,3-dio-cxane-4-acetate
• (4R,6R)-t-Butyl-6-AMINOMETHYL-2,2-dimethyl-1,3-dioxane-4-acetate
• (4R,6R)-t-butyl-6-cyanomethyl02,2-dimethyl-1,3-dioxane-4-acetate
• ATS 8 (4R,CIS)-1,1-DIMETHYLETHY-L-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE
• TERT-BUTYL[(4R,6R)-6-CYANOMETHYL-1,3-DIOXAN-4-YL]ACETATE
• (4R-cis)-1,1-dimethylethyl-6-cyanomethyl-2,2-dimethyl-1,3-dloxane-4-acetate

tert-Butyl (4R,6R)-6-Cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate

CAS: 125971-94-0

Fórmula: C₁₄H₂₃NO₄

Pureza: >98.0%(GC)(N)

Forma y color: White to Almost white powder to crystal

Peso molecular: 269.34

Ref: 3B-B3642

1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6R)-

CAS: 125971-94-0

Fórmula: C₁₄H₂₃NO₄

Pureza: 95%

Forma y color: Solid

Peso molecular: 269.3367

Ref: IN-DA000QLY

Tert-Butyl 2-((4R,6R)-6-(Cyanomethyl)-2,2-Dimethyl-1,3-Dioxan-4-yl)Acetate

CAS: 125971-94-0

Tert-Butyl 2-((4R,6R)-6-(Cyanomethyl)-2,2-Dimethyl-1,3-Dioxan-4-yl)Acetate

Pureza: 99%

Peso molecular: 269.34g/mol

Ref: 54-OR1015132

Atorvastatin Impurity 21

CAS: 125971-94-0

Fórmula: C₁₄H₂₃NO₄

Forma y color: White To Off-White Solid

Peso molecular: 269.34

Ref: 4Z-A-1257

1,1-Dimethylethyl 2-[(4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate

CAS: 125971-94-0

Forma y color: Neat

Ref: 86-MM0400.37

(4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester

Producto controlado

CAS: 125971-94-0

Applications (4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester is an intermediate of Atorvastatin (A791750, Ca salt), a selective, competitive HMG-CoA reductase . Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.
References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993), Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996), Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000),

Fórmula: C₁₄H₂₃NO₄

Forma y color: Neat

Peso molecular: 269.34

Ref: TR-C982020

tert-Butyl (4R,6R)-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate

CAS: 125971-94-0

tert-Butyl (4R,6R)-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate is a high quality and versatile chemical reagent that has been widely used in the synthesis of complex compounds. It is an intermediate for the production of fine chemicals and speciality chemicals. It can be used as a building block for various chemical reactions because it is a versatile building block with many functional groups that are reactive under different conditions.

Fórmula: C₁₄H₂₃NO₄

Pureza: Min. 98.0 Area-%

Peso molecular: 269.34 g/mol

Ref: 3D-Q-102783

Atorvastatin Acetonide t-Butyl Ester Side Chain (4R,6R)-Isomer

CAS: 125971-94-0

Fórmula: C₁₄H₂₃NO₄

Peso molecular: 269.34

Ref: ST-EA-CP-A32061