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CAS 126253-57-4

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  • L-(+)-2-Amino-6-phosphonohexanoic acid
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    L-(+)-2-Amino-6-phosphonohexanoic acid

    CAS:
    <p>L-(+)-2-Amino-6-phosphonohexanoic acid is a selective inhibitor of the glutamate transporter EAAT1. It blocks the uptake and transport of glutamate into astrocytes, which sensitizes neurons to the neurotoxic effects of this neurotransmitter. L-(+)-2-Amino-6-phosphonohexanoic acid is also an endogenous amino acid that is phosphorylated by protein kinase C to form a phosphonate, which can sequester extracellular glutamate. The interaction between L-(+)-2-Amino-6-phosphonohexanoic acid and l-ap6 has been shown to be important for regulating the uptake of glutamate in vivo.</p>
    Fórmula:C6H14NO5P
    Pureza:Min. 95%
    Peso molecular:211.15 g/mol

    Ref: 3D-BFA25357

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