CAS 1264-62-6

Eritromicina etilsuccinato

Descripción:

Eritromicina etilsuccinato es un antibiótico que pertenece a la clase de los macrólidos, utilizado principalmente para tratar diversas infecciones bacterianas. Es un derivado semisintético de la eritromicina, que mejora su estabilidad y biodisponibilidad. El compuesto se caracteriza por su capacidad para inhibir la síntesis de proteínas bacterianas al unirse a la subunidad ribosomal 50S, lo que lo hace efectivo contra una variedad de bacterias Gram-positivas y algunas Gram-negativas. Eritromicina etilsuccinato se administra típicamente por vía oral y a menudo se formula como un profármaco, que se convierte en eritromicina en el cuerpo. Se conoce por su toxicidad y efectos secundarios relativamente bajos, aunque pueden ocurrir trastornos gastrointestinales. La sustancia es soluble en disolventes orgánicos pero tiene una solubilidad limitada en agua, lo que influye en su formulación y entrega. Además, es importante considerar las posibles interacciones medicamentosas y los patrones de resistencia al usar este antibiótico en entornos clínicos. En general, Eritromicina etilsuccinato sigue siendo una opción valiosa en el tratamiento de infecciones, particularmente en pacientes que son alérgicos a la penicilina.

Fórmula: C₄₃H₇₅NO₁₆

InChI: InChI=1S/C43H75NO16/c1-15-29-43(11,52)36(48)24(5)33(47)22(3)20-41(9,51)38(25(6)34(26(7)39(50)57-29)59-32-21-42(10,53-14)37(49)27(8)56-32)60-40-35(28(44(12)13)19-23(4)55-40)58-31(46)18-17-30(45)54-16-2/h22-29,32,34-38,40,48-49,51-52H,15-21H2,1-14H3/t22-,23-,24+,25+,26-,27+,28+,29-,32+,34+,35-,36-,37+,38-,40+,41-,42-,43-/m1/s1

Clave InChI: InChIKey=NSYZCCDSJNWWJL-YXOIYICCSA-N

SMILES: O(C(CCC(OCC)=O)=O)[C@H]1[C@H](O[C@@H]2[C@@H](C)[C@H](O[C@H]3C[C@](OC)(C)[C@@H](O)[C@H](C)O3)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]2(C)O)O[C@H](C)C[C@@H]1N(C)C

Sinónimos:

• (2R,3S,4R,6S)-4-(dimethylamino)-2-{[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl]oxy}-6-methyltetrahydro-2H-pyran-3-yl ethyl butanedioate (non-preferred name)
• (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydropyran-2-yl]oxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
• 4-(dimethylamino)-2-({14-ethyl-7,12,13-trihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy]-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl}oxy)-6-methyltetrahydro-2H-pyran-3-yl ethyl butanedioate (non-preferred name)
• 4-Ethoxy-4-Oxo-Butanoate
• Anamycin
• Arpimycin
• Durapaediat
• E-Mycin e
• Eritrocina
• EryPed
• Eryliquid
• Erythro ES
• Erythro-Holz
• Erythrocin ethyl succinate
• Erythromycin Ethly Succinate.
• Erythromycin Ethyl Succinate
• Erythromycin Ethylsuccinate
• Erythromycin, 2′-(ethyl butanedioate)
• Erythromycin, 2′-(ethyl succinate)
• Erythromycin, mono(ethyl succinate) (ester)
• Erythroped
• Esinol
• Evesin
• Monomycin
• Oxacyclotetradecane, erythromycin deriv.
• Paediathrocin
• Pediamycin
• Refkas
• Sigapedil
• Succinic acid, ethyl ester, monoester with erythromycin

Erythromycin ethyl succinate

CAS: 1264-62-6

Erythromycin ethyl succinate

Fórmula: C₄₃H₇₅NO₁₆

Forma y color: Off-White

Peso molecular: 862.0527

Ref: 47-798

ERYTHROMYCIN ETHYLSUCCINATE RS

CAS: 1264-62-6

ERYTHROMYCIN ETHYLSUCCINATE RS

Fórmula: C₄₃H₇₅NO₁₆

Peso molecular: 862.0527

Ref: 41-ICRS46470

ERYTHROMYCIN ETHYLSUCCINATE CRS

CAS: 1264-62-6

ERYTHROMYCIN ETHYLSUCCINATE CRS

Fórmula: C₄₃H₇₅NO₁₆

Peso molecular: 862.0527

Ref: 41-E1500000

ERYTHROMYCIN ETHYLSUCCINATE FOR IMPURITY P IDENTIFICATION CRS

CAS: 1264-62-6

ERYTHROMYCIN ETHYLSUCCINATE FOR IMPURITY P IDENTIFICATION CRS

Fórmula: C₄₃H₇₅NO₁₆

Peso molecular: 862.0527

Ref: 41-Y0001845

Erythromycin Ethylsuccinate

CAS: 1264-62-6

Erythromycin and its derivatives; salts thereof

Fórmula: C₄₃H₇₅NO₁₆

Forma y color: White Powder

Peso molecular: 861.50859

Ref: 45-1245008

(2S,3R,4S,6R)-4-(dimethylamino)-2-{[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-2,10-dioxo-1-oxacyclotetradecan-6-yl]oxy}-6-methyloxan-3-yl 1-ethyl butanedioate

CAS: 1264-62-6

Fórmula: C₄₃H₇₅NO₁₆

Forma y color: Solid

Peso molecular: 862.0527

Ref: IN-DA000SQT

Erythromycin ethylsuccinate

CAS: 1264-62-6

Erythromycin ethylsuccinate (EES) is a macrolide antibiotic, produced by Streptomyces erythreus.

Fórmula: C₄₃H₇₅NO₁₆

Pureza: 77% - 98%

Forma y color: White Or Slightly Yellow Crystalline Powder White To Yellowish Crystalline Solid

Peso molecular: 862.05

Ref: TM-T0474

Erythromycin ethylsuccinate

CAS: 1264-62-6

Erythromycin ethylsuccinate

Pureza: ≥70%

Peso molecular: 862.05g/mol

Ref: 54-BUP16717

Erythromycin Ethylsuccinate

CAS: 1264-62-6

Erythromycin Ethylsuccinate

Pureza: ≥765IU/mg

Peso molecular: 862.05g/mol

Ref: 54-OR1027491

Erythromycin Ethylsuccinate-13C-d3

CAS: 1264-62-6

Fórmula: C₄₂₁₃CH₇₂D₃NO₁₆

Forma y color: White To Off-White Solid

Peso molecular: 866.07

Ref: 4Z-E-2015

Erythromycin Ethylsuccinate

CAS: 1264-62-6

Fórmula: C₄₃H₇₅NO₁₆

Forma y color: White To Off-White Solid

Peso molecular: 862.06

Ref: 4Z-E-2040

Erythromycin-ethyl succinate

Producto controlado

CAS: 1264-62-6

Fórmula: C₄₃H₇₅NO₁₆

Forma y color: Neat

Peso molecular: 862.05

Ref: 04-C13203520

Erythromycin Ethylsuccinate-D5

CAS: 1264-62-6

Fórmula: C₄₃H₇₀NO₁₆D₅

Peso molecular: 867.10

Ref: 4Z-E-2014

Erythromycin Ethyl Succinate

CAS: 1264-62-6

Fórmula: C₄₃H₇₅NO₁₆

Peso molecular: 862.05

Ref: ST-EA-CP-E18015

Erythromycin Ethyl Succinate

Producto controlado

CAS: 1264-62-6

Applications Erythromycin Ethyl Succinate is a derivative of Erythromycin (E649950), an antibiotic.
References Koch, W.L., et al.: Anal. Profiles Drug Subs., 8, 157 (1979); Serisier, D. et al.: J. Am. Med. Assoc., 309, 1206 (2013);

Fórmula: C₄₃H₇₅NO₁₆

Forma y color: Off-White

Peso molecular: 862.05

Ref: TR-E649985

Erythromycin Ethyl Succinate-13C,d3

Producto controlado

CAS: 1264-62-6

Applications Erythromycin Ethyl Succinate-13C,d3 is the deuterated form of Erythromycin Ethyl Succinate (E649985), which is a derivative of Erythromycin (E649950), an antibiotic.
References Koch, W.L., et al.: Anal. Profiles Drug Subs., 8, 157 (1979); Serisier, D. et al.: J. Am. Med. Assoc., 309, 1206 (2013);

Fórmula: CC₄₂D₃H₇₂NO₁₆

Forma y color: Neat

Peso molecular: 866.064

Ref: TR-E649986

Erythromycin ethyl succinate

CAS: 1264-62-6

Erythromycin ethyl succinate is an ester prodrug that is formed by the reaction of erythromycin and ethylsuccinic acid. It has a broad spectrum of activity against Gram-positive and Gram-negative bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and Mycobacterium tuberculosis. Erythromycin ethyl succinate is also active against Haemophilus influenzae, Moraxella catarrhalis, Chlamydia pneumoniae, Legionella pneumophila, Helicobacter pylori, Leptospira interrogans, Bordetella pertussis, Rickettsia rickettsii, Borrelia burgdorferi, Coxiella burnetii, and Mycoplasma pneumoniae. Erythromycin ethyl succinate has been shown to be effective in treating streptococcal pharyngitis and tissue infections.

Fórmula: C₄₃H₇₅NO₁₆

Pureza: Min. 95%

Peso molecular: 862.05 g/mol

Ref: 3D-FE170906