CAS 1268997-70-1

Lapatinib Impurity 1 (O-De(3-fluorobenzyl) Lapatinib)

CAS: 1268997-70-1

Fórmula: C₂₂H₂₁ClN₄O₄S

Forma y color: Yellow Solid

Peso molecular: 472.94

Ref: 4Z-L-256

Lapatinib Impurity 1 (O-De(3-fluorobenzyl) Lapatinib) Ditosylate Salt

CAS: 1268997-70-1

Fórmula: C₂₂H₂₁ClN₄O₄S·2C₇H₈O₃S

Forma y color: Yellow Solid

Peso molecular: 472.95 2 172.20

Ref: 4Z-L-254

O-De(3-fluorobenzyl) Lapatinib Ditosylate Salt

Producto controlado

CAS: 1268997-70-1

Applications A reactive metabolite of Lapatinib (L175800) which is associated with various drug toxicities. Lapatinib is metabolized mainly by P450 3A4 to form O- and N-dealkylated metabolites.
References He, K., et al.: Chem. Res. Toxicol., 11, 252 (1998), Rusnuk, D., et al.: Cancer Res., 61, 7196 (2001), Li, X., et al.: Drug Metab. Dispos., 37, 1242 (2009),

Fórmula: C₃₆H₃₇ClN₄O₁₀S₃

Forma y color: Neat

Peso molecular: 817.35

Ref: TR-D228750

Lapatinib Impurity 1

CAS: 1268997-70-1

Fórmula: C₂₂H₂₁ClN₄O₄S

Peso molecular: 472.94

Ref: ST-EA-CP-L46005