CAS 12771-72-1

verruculógeno de penicillium verruculosum

Descripción:

La verruculogen es una micotoxina producida por el hongo Penicillium verruculosum, clasificada en la categoría de alcaloides indólicos. Este compuesto se caracteriza por su estructura compleja, que incluye un marco bicíclico y múltiples grupos funcionales, lo que contribuye a su actividad biológica. La verruculogen exhibe propiedades neurotóxicas, afectando la liberación de neurotransmisores y potencialmente llevando a efectos adversos en el sistema nervioso. Se ha estudiado por sus posibles implicaciones en la seguridad alimentaria, ya que puede contaminar varios productos agrícolas. El compuesto también es de interés en la investigación farmacológica debido a su mecanismo de acción único y sus posibles aplicaciones terapéuticas. Sin embargo, su toxicidad requiere un manejo y regulación cuidadosos. En términos de solubilidad, la verruculogen es típicamente soluble en disolventes orgánicos, lo cual es común para muchas micotoxinas. En general, aunque la verruculogen presenta avenidas intrigantes para la investigación, su perfil toxicológico subraya la importancia de monitorear y controlar su presencia en productos alimenticios y de alimentación.

Fórmula: C₂₇H₃₃N₃O₇

InChI: InChI=1S/C27H33N3O7/c1-14(2)11-20-29-18-12-15(35-5)8-9-16(18)21-22(29)19(13-26(3,4)37-36-20)30-24(32)17-7-6-10-28(17)25(33)27(30,34)23(21)31/h8-9,11-12,17,19-20,23,31,34H,6-7,10,13H2,1-5H3/t17-,19-,20+,23-,27+/m0/s1

Clave InChI: InChIKey=LRXYHMMJJCTUMY-GWXUGYLUSA-N

SMILES: C(=C(C)C)[C@@H]1N2C3=C(C=4C2=CC(OC)=CC4)[C@H](O)[C@]5(O)N([C@]3(CC(C)(C)OO1)[H])C(=O)[C@]6(N(C5=O)CCC6)[H]

Sinónimos:

• (5R,10S,10aR,14aS,15bS)-1,10,10a,14,14a,15b-Hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propen-1-yl)-5H,12H-3,4-dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione
• 10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methylprop-1-en-1-yl)-1,10,10a,14,14a,15b-hexahydro-12H-3,4-dioxa-5a,11a,15a-triazacycloocta[1,2,3-lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione
• 5H,12H-3,4-Dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione, 1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propen-1-yl)-, (5R,10S,10aR,14aS,15bS)-
• 5H,12H-3,4-Dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione, 1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-, (5R,10S,10aR,14aS,15bS)-
• 5H,12H-3,4-Dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione, 1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-, [5R-(5α,10α,10aα,14aα,15bα)]-
• Na 209A
• TR 1 toxin
• Verruculogen
• Verruculogen TR 1
• Verruculogen, Penicillium verruculosum
• GWIWVUJHTCZBOP-FCXIIMTCSA-N
• tr1
• (5R)-1,10,10a,14,14aα,15bα-Hexahydro-10α,10aα-dihydroxy-7-methoxy-2,2-dimethyl-5α-(2-methyl-1-propenyl)-12H-3,4-dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione
• Taste receptor type 1 member 1
• VERRUCULOGEN FROM PENICILLIUM VERRUCULOS
• verruculogen from penicillium*verruculosum
• Verruculogen NA 209A TR 1 toxin
• ANTI-TAS1R1 (CENTER) antibody produced in rabbit
• TRXR1
• TAS1R1
• MGC9145
• Verruculogen solution
• (5R)-2,5,10,10a,11,12,13,14,14aα,15bα-Decahydro-10α,10aα-dihydroxy-7-methoxy-2,2-dimethyl-5α-(2-methyl-1-propenyl)-3,4-dioxa-5a,11a,15a-triaza-1H-cyclooct[lm]indeno[5,6-b]fluorene-11,15-dione
• (5R-(5alpha,10 alpha,10Aalpha,14aalpha,15balpha))-1,10,10A,14,14A,15B-hexahydro-10,10A-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-5H,12H-3,4-dioxa-5A,11A,15A-triaza cyclooct (1m) indeno (5,6-B)fluorene-11,15(2H,13H)-dione
• TR-1TOXIN
• verruculogentr1
• 5H,12H-3,4-Dioxa-5A,11A,15A-triazacyclooct(lm)indeno(5,6-B)fluorene-11,15(2H,13H)-dione, 1,10,10A,14,14A,15B-hexahydro-10,10A-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-,(5R-(5-alpha,10-alpha,10A-alpha,14A-alpha-15B-alpha))-
• GPR70
• yl-5-(2-methyl-1-propenyl)-,(5r-(5-alpha,10-alpha,10a-alpha,14a-alpha-15b-alp
• GRIM-12
• Anti-TAS1R1 (N-terminal) antibody produced in rabbit
• 3h)-dione,1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimeth
• T1R1
• 5h,12h-3,4-dioxa-5a,11a,15a-triazacyclooct(lm)indeno(5,6-b)fluorene-11,15(2h,1
• VERRUCOLOGEN
• Anti-TAS1R1 (C-terminal) antibody produced in rabbit
• TXNRD1 human

Verruculogen

CAS: 12771-72-1

Fórmula: C₂₇H₃₃N₃O₇

Pureza: 98.89%

Forma y color: Brownish. Amorphous solid

Peso molecular: 511.0

Ref: 8R-AD0189

5H,12H-3,4-Dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione,1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-, (5R,10S,10aR,14aS,15bS)-

CAS: 12771-72-1

Fórmula: C₂₇H₃₃N₃O₇

Pureza: 95%

Forma y color: Solid

Peso molecular: 511.5668

Ref: IN-DA00VQYN

Verruculogen from Penicillium verruculosum

CAS: 12771-72-1

Verruculogen from Penicillium verruculosum

Fórmula: C₂₇H₃₅N₃O₇

Pureza: By hplc: 97.52% (Typical Value in Batch COA)

Forma y color: white powder

Peso molecular: 513.58g/mol

Ref: 54-BIV1002

Verruculogen

CAS: 12771-72-1

Verruculogen, a toxin from Penicillium/Aspergillus, blocks Ca2+-K+ channels and halts mammalian M phase.

Fórmula: C₂₇H₃₃N₃O₇

Pureza: 98%

Forma y color: White Powder

Peso molecular: 511.57

Ref: TM-T13297

Verruculogen

CAS: 12771-72-1

Fórmula: C₂₇H₃₃N₃O₇

Pureza: ≥ 95.0%

Forma y color: Off-white to brown solid

Peso molecular: 511.6

Ref: 7W-GL5203

Verruculogen

CAS: 12771-72-1

Applications Verruculogen is a mycotoxin and novel mammalian cell cycle inhibitors produced by Aspergillus fumigatus.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cui, C. et al.: Jour. of Ant., 49(6), 527-533, (1996)

Fórmula: C₂₇H₃₃N₃O₇

Forma y color: Neat

Peso molecular: 511.57

Ref: TR-V267190

Verruculogen

CAS: 12771-72-1

Verruculogen is a mycotoxin, which is derived from certain species of fungi, primarily those in the genera Aspergillus and Penicillium. It is synthesized by these fungi during their secondary metabolic processes. As a chemical compound, verruculogen acts by inhibiting calcium channels in nerve cells, disrupts neurotransmitter release, and affects neuronal activity. This mode of action is crucial in understanding its role in toxicology and pharmacology.

Pureza: Min. 95%

Ref: 3D-BV162751