CAS 128-46-1

Dihidroestreptomicina

Descripción:

Dihidroestreptomicina es un antibiótico aminoglucósido que se deriva de la bacteria Streptomyces griseus. Se utiliza principalmente en el tratamiento de diversas infecciones bacterianas, particularmente aquellas causadas por Mycobacterium tuberculosis. El compuesto exhibe un amplio espectro de actividad contra bacterias gramnegativas y algunas grampositivas al inhibir la síntesis de proteínas mediante la unión a la subunidad ribosomal 30S. Dihidroestreptomicina se caracteriza por su relativamente baja solubilidad en agua, lo que puede influir en su farmacocinética y biodisponibilidad. Se administra típicamente por inyección debido a su mala absorción oral. La sustancia puede causar efectos secundarios, incluyendo nefrotoxicidad y ototoxicidad, que son preocupaciones comunes con los aminoglucósidos. Su estructura química presenta múltiples grupos amino, lo que contribuye a su basicidad e interacción con los ribosomas bacterianos. Dihidroestreptomicina se utiliza a menudo en combinación con otros antibióticos para mejorar la eficacia terapéutica y reducir el riesgo de desarrollo de resistencia. Al igual que con todos los antibióticos, se recomienda realizar pruebas de susceptibilidad adecuadas para garantizar un tratamiento efectivo.

Fórmula: C₂₁H₄₁N₇O₁₂

InChI: InChI=1S/C21H41N7O12/c1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35/h5-18,26,29-36H,3-4H2,1-2H3,(H4,22,23,27)(H4,24,25,28)/t5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+/m0/s1

Clave InChI: InChIKey=ASXBYYWOLISCLQ-HZYVHMACSA-N

SMILES: O([C@H]1[C@H](O[C@@H]2[C@@H](NC(=N)N)[C@H](O)[C@@H](NC(=N)N)[C@H](O)[C@H]2O)O[C@@H](C)[C@@]1(CO)O)[C@H]3[C@@H](NC)[C@H](O)[C@@H](O)[C@H](CO)O3

Sinónimos:

• 2,2'-[(1R,2R,3S,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-(hydroxymethyl)-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine
• 2,4-Diguanidino-3,5,6-trihydroxycyclohexyl-5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-hydroxymethyl-beta-L-lyxo-pentanofuranoside
• 2,4-Diguanidino-3,5,6-trihydroxycyclohexyl-5-deoxy-2-O-(2-deoxy-2-methylamino-α-<span class="text-smallcaps">L</smallcap>-glucopyranosyl)-3-hydroxymethyl-β-<smallcap>L</span>-lyxo-pentanofuranoside
• 2,4-Diguanidino-3,5,6-trihydroxycyclohexyl-5-deoxy-2-O-(2-deoxy-2-methylamino-α-L-glucopyranosyl)-3-hydroxymethyl-β-L-lyxo-pentanofuranoside
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-deoxy-2-(methylamino)-α-<smallcap>L</smallcap>-glucopyranosyl-(1→2)-O-5-deoxy-3-C-(hydroxymethyl)-α-<smallcap>L</span>-lyxofuranosyl-(1→4)-N,N′-bis(aminoiminomethyl)-
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-deoxy-2-(methylamino)-α-<smallcap>L</smallcap>-glucopyranosyl-(1→2)-O-5-deoxy-3-C-(hydroxymethyl)-α-<smallcap>L</span>-lyxofuranosyl-(1→4)-N¹,N³-bis(aminoiminomethyl)-
• Abiocine
• D-Streptamine, O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-(hydroxymethyl)-α-L-lyxofuranosyl-(1→4)-N,N'-bis(aminoiminomethyl)-
• D-Streptamine, O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-(hydroxymethyl)-α-L-lyxofuranosyl-(1→4)-N1,N3-bis(aminoiminomethyl)-
• DST
• Dhms
• Dhsm
• Dihidroestreptomicina
• Dihydrostreptomycine
• Dihydrostreptomycinum
• Diidrostreptomicina
• N'',N'''''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-L-glycero-hexopyranosyl]-3-C-(hydroxymethyl)-beta-D-glycero-pentofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine sulfate (salt)
• N'',N'''''-[(1S,2S,3R,4S,5S,6R)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-(hydroxymethyl)-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine
• O-2-Deoxy-2-(methylamino)-α-<span class="text-smallcaps">L</smallcap>-glucopyranosyl-(1→2)-O-5-deoxy-3-C-(hydroxymethyl)-α-<smallcap>L</smallcap>-lyxofuranosyl-(1→4)-N¹,N³-bis(aminoiminomethyl)-<smallcap>D</span>-streptamine
• Streptamine, O-beta-D-mannopyranosyl-(1-4)-2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl-(1-2)-5-deoxy-O-3-C-(hydroxymethyl)-alpha-L-lyxofuranosyl-(1-4)-N,N'-diamidino-, D-
• Streptomycin, deoxydihydrohydroxy-
• Streptomycin, dihydro-
• Unii-P2I6R8W6Ua
• Vibriomycin

THIRD INTERNATIONAL STANDARD FOR DIHYDROSTREPTOMYCIN

CAS: 128-46-1

THIRD INTERNATIONAL STANDARD FOR DIHYDROSTREPTOMYCIN

Fórmula: C₂₁H₄₁N₇O₁₂

Peso molecular: 583.5899

Ref: 41-ISA42688

Dihydrostreptomycin 1000 µg/mL in Water

Producto controlado

CAS: 128-46-1

Fórmula: C₂₁H₄₁N₇O₁₂

Forma y color: Single Solution

Peso molecular: 583.59

Ref: 04-A12635200WA-1000

Dihydrostreptomycin

CAS: 128-46-1

Dihydrostreptomycin is an aminoglycoside antibiotic with action on bacterial protein synthesis inhibition and is used for treating tuberculosis and bacterial infections in veterinary medicine.

Fórmula: C₂₁H₄₁N₇O₁₂

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 583.59 g/mol

Ref: 3D-AD29660

Dihydrostreptomycin

CAS: 128-46-1

Dihydrostreptomycin is an antibiotic.

Fórmula: C₂₁H₄₁N₇O₁₂

Pureza: 98%

Forma y color: Slightly Beige Solid

Peso molecular: 583.59

Ref: TM-T19806