CAS 128-57-4

Sennósido B

Descripción:

Sennósido B, con el número CAS 128-57-4, es un compuesto natural derivado principalmente de las hojas y las cápsulas de la planta de Senna, particularmente Senna alexandrina. Pertenece a una clase de compuestos conocidos como antraquinonas, que se caracterizan por su estructura aromática policíclica. Sennósido B es reconocido por sus propiedades laxantes, funcionando como un laxante estimulante al promover la peristalsis en los intestinos. A menudo se utiliza en la medicina herbal y en formulaciones de laxantes de venta libre. El compuesto se encuentra típicamente en forma de un polvo amarillento y es soluble en agua, lo que facilita su absorción y eficacia en el tracto gastrointestinal. Además de sus efectos laxantes, se ha estudiado Sennósido B por sus posibles propiedades antioxidantes y antiinflamatorias. Sin embargo, su uso debe ser abordado con precaución, ya que el consumo excesivo puede llevar a efectos adversos como calambres abdominales y diarrea. En general, Sennósido B es un compuesto significativo tanto en prácticas medicinales tradicionales como modernas, particularmente en el tratamiento del estreñimiento.

Fórmula: C₄₂H₃₈O₂₀

InChI: InChI=1/C42H38O20/c43-11-23-31(47)35(51)37(53)41(61-23)59-21-5-1-3-15-25(17-7-13(39(55)56)9-19(45)27(17)33(49)29(15)21)26-16-4-2-6-22(60-42-38(54)36(52)32(48)24(12-44)62-42)30(16)34(50)28-18(26)8-14(40(57)58)10-20(28)46/h1-10,23-26,31-32,35-38,41-48,51-54H,11-12H2,(H,55,56)(H,57,58)/t23-,24-,25-,26+,31-,32-,35+,36+,37-,38-,41-,42-/m1/s1

Clave InChI: InChIKey=IPQVTOJGNYVQEO-AIFLABODSA-N

SMILES: O=C1C=2C([C@@](C=3C1=C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C=CC3)([C@@]5(C=6C(C(=O)C=7C5=CC=CC7O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)=C(O)C=C(C(O)=O)C6)[H])[H])=CC(C(O)=O)=CC2O

Sinónimos:

• (9R,9'S)-5,5'-bis(beta-D-glucopyranosyloxy)-4,4'-dihydroxy-10,10'-dioxo-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid
• (9R,9′S)-5,5′-Bis(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-10,10′-dioxo[9,9′-bianthracene]-2,2′-dicarboxylic acid
• Nsc 112930
• Unii-F887D1637W
• [9,9′-Bianthracene]-2,2′-dicarboxylic acid, 5,5′-bis(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-10,10′-dioxo-, (9R,9′S)-
• [9,9′-Bianthracene]-2,2′-dicarboxylic acid, 5,5′-bis(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-10,10′-dioxo-, (R*,S*)-
• [9,9′-Bianthracene]-2,2′-dicarboxylic acid, 5,5′-bis(β-D-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-10,10′-dioxo-, (R*,S*)-
• Sennoside B
• (9R,9′S)-5,5′-Bis(β-D-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-10,10′-dioxo[9,9′-bianthracene]-2,2′-dicarboxylic acid
• [9,9′-Bianthracene]-2,2′-dicarboxylic acid, 5,5′-bis(β-D-glucopyranosyloxy)-9,9′,10,10′-tetrahydro-4,4′-dihydroxy-10,10′-dioxo-, (9R,9′S)-
• SENNIDINE B(RG)
• Sennoside B std.
• SENNOSIDE B WITH HPLC
• (9S,9'R)-5,5'-Bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-9,9'-bianthracene-2,2'-dicarboxylic acid
• PURSENNIDE
• (9S)-9-[(9R)-2-Carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid
• SENNOSIDE B hplc
• SENNOSIDE B(SH)
• [9,9'-Bianthracene]-2,2'-dicarboxylicacid,5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-,(9R,9'S)-
• (9S)-9-[(9R)-2-carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid
• 9,9-Bianthracene-2,2-dicarboxylic acid, 5,5-bis(.beta.-D-glucopyranosyloxy)-9,9,10,10-tetrahydro-4,4-dihydroxy-10,10-dioxo-, (9R,9S)-
• SENNOSIDE B(P)
• SENNOSIDE B 96.5+%
• GLYSENNIDE

Sennoside B

CAS: 128-57-4

Sennoside B analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₄₂H₃₈O₂₀

Pureza: (HPLC) ≥97%

Forma y color: Powder

Peso molecular: 862.75

Ref: 11-0457S

SENNOSIDE B CRS

CAS: 128-57-4

SENNOSIDE B CRS

Ref: 41-Y0002143

Sennoside B

CAS: 128-57-4

Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives

Fórmula: C₄₂H₃₈O₂₀

Forma y color: Yellow Powder

Peso molecular: 862.19564

Ref: 45-1612029

[9,9'-Bianthracene]-2,2'-dicarboxylic acid, 5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-, (9R,9'S)-

CAS: 128-57-4

Fórmula: C₄₂H₃₈O₂₀

Pureza: 98%

Forma y color: Solid

Peso molecular: 862.7391

Ref: IN-DA000XNT

Sennoside B

CAS: 128-57-4

Sennoside B

Pureza: 97%

Peso molecular: 862.74g/mol

Ref: 54-OR1023616

Sennoside B

CAS: 128-57-4

Fórmula: C₄₂H₃₈O₂₀

Pureza: ≥ 98.0%

Forma y color: Yellow powder

Peso molecular: 862.74

Ref: 7W-GC2469

Sennoside B

CAS: 128-57-4

Sennoside B

Pureza: ≥90%

Peso molecular: 862.74g/mol

Ref: 54-BUP00060

Sennoside B

CAS: 128-57-4

Fórmula: C₄₂H₃₈O₂₀

Pureza: 95%~99%

Peso molecular: 862.746

Ref: BP-BP1293

Sennoside B

CAS: 128-57-4

Fórmula: C₄₂H₃₈O₂₀

Pureza: >95.0%(HPLC)

Forma y color: White to Yellow to Yellow green powder to crystal

Peso molecular: 862.75

Ref: 3B-E1546

Sennoside B

CAS: 128-57-4

Fórmula: C₄₂H₃₈O₂₀

Peso molecular: 862.75

Ref: 4Z-S-078004

Sennoside B

CAS: 128-57-4

Sennoside B is an anthranoid. Anthranoid derivatives are used all over the world as a treatment for constipation.

Fórmula: C₄₂H₃₈O₂₀

Pureza: 92.85% - 98.92%

Forma y color: Light Yellow Crystal

Peso molecular: 862.74

Ref: TM-T2734

Sennoside B RS

CAS: 128-57-4

Forma y color: Yellow Solid Crystals To Powder

Ref: 2K-1078000021

Sennoside b

CAS: 128-57-4

Natural glycoside

Fórmula: C₄₂H₃₈O₂₀

Pureza: ≥ 90.0 % (HPLC)

Forma y color: Powder

Peso molecular: 862.75

Ref: 5G-89277

Sennoside B

CAS: 128-57-4

Fórmula: C₄₂H₃₈O₂₀

Forma y color: Light Yellow To Dark Yellow

Peso molecular: 862.74

Ref: TR-S258810

Sennoside B

CAS: 128-57-4

Fórmula: C₄₂H₃₈O₂₀

Peso molecular: 862.75

Ref: ST-EA-CP-S57002

Sennoside B

CAS: 128-57-4

Sennoside B is a natural laxative derived from the leaves and pods of senna plants, specifically Cassia angustifolia and Cassia acutifolia. As an anthraquinone glycoside, its structure comprises a sugar moiety linked to an aglycone, which is responsible for its pharmacological activity. The mode of action of Sennoside B involves its biotransformation by gut bacteria in the colon, where it is converted into its active form, rhein anthrone. This active metabolite stimulates the mucosal lining of the colon and alters electrolyte transport across the intestinal epithelium. The result is increased peristaltic contractions and an augmented influx of water into the colon, leading to bowel movement facilitation.

Fórmula: C₄₂H₃₈O₂₀

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 862.74 g/mol

Ref: 3D-MS08137