CAS 128-62-1

1(3H)-Isobenzofuranona, 6,7-dimetoxi-3-[(5R)-5,6,7,8-tetrahidro-4-metoxi-6-metil-1,3-dioxolo[4,5-g]isoquinolin-5-il]-, (3S)-

Descripción:

1(3H)-Isobenzofuranona, 6,7-dimetoxi-3-[(5R)-5,6,7,8-tetrahidro-4-metoxi-6-metil-1,3-dioxolo[4,5-g]isoquinolin-5-il]-, (3S)-, conocido por su número CAS 128-62-1, es un compuesto orgánico complejo caracterizado por sus características estructurales únicas, que incluyen un núcleo de isobenzofuranona fusionado y un moiety de dioxoloisoquinolina. Este compuesto exhibe una variedad de grupos funcionales, incluidos grupos metoxi y dioxole, que contribuyen a su reactividad química y potencial actividad biológica. Típicamente es un sólido a temperatura ambiente y puede exhibir solubilidad moderada en disolventes orgánicos. La estereoquímica indicada por las designaciones (5R) y (3S) sugiere arreglos espaciales específicos de átomos, que pueden influir en las interacciones del compuesto en sistemas biológicos. Tales compuestos son a menudo de interés en la química medicinal debido a sus propiedades farmacológicas potenciales, incluidas actividades antiinflamatorias o anticancerígenas. Sin embargo, se necesitan estudios detallados para elucidar completamente sus propiedades y aplicaciones en varios campos, incluidos productos farmacéuticos y síntesis orgánica.

Fórmula: C₂₂H₂₃NO₇

InChI: InChI=1/C22H23NO7.ClH/c1-23-8-7-11-9-14-20(29-10-28-14)21(27-4)15(11)17(23)18-12-5-6-13(25-2)19(26-3)16(12)22(24)30-18;/h5-6,9,17-18H,7-8,10H2,1-4H3;1H/t17-,18-;/m1./s1

Clave InChI: InChIKey=AKNNEGZIBPJZJG-MSOLQXFVSA-N

SMILES: O(C)C=1C=2[C@@](N(C)CCC2C=C3C1OCO3)([C@@]4(C=5C(C(=O)O4)=C(OC)C(OC)=CC5)[H])[H]

Sinónimos:

• (-)-Narcotine
• (-)-α-Narcotine
• (3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone
• 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[ 4,5-g]isoquinolin-5-yl)-, [S-(R*,S*)]-
• 1,3-Dioxolo[4,5-g]isoquinoline, 1(3H)-isobenzofuranone deriv.
• 1-α-Narcotine
• <span class="text-smallcaps">L</span>-α-Noscapine
• Capval
• Coscopin
• Coscotabs
• L-α-Noscapine
• Longactin
• Longatin
• Lyobex
• Methoxyhydrastine
• Narcompren
• Narcosine
• Narcotin
• Narcotussin
• Narkotin
• Nectadon
• Nicolane
• Nipaxon
• Noscapalin
• Noscapin
• Noscapina
• Noscapine
• Nsc 5366
• O-Methylarcotoline
• O-Methylnarcotoline
• Opian
• Opianin
• Opianine
• Terbenol
• Tusscapine
• Vadebex
• l-α-Narcotine
• 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, (3S)-
• (3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-2-benzofuran-1(3H)-one
• (3R)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-2-benzofuran-1(3H)-one
• 6,7-dimethoxy-3-(4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-2-benzofuran-1(3H)-one
• (3R)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-2-benzofuran-1(3H)-one hydrochloride
• 6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-isobenzofuran-1-one
• tusseapine
• L-α-Narcotin
• l-alpha-2-methyl-8-methoxy-6,7-methylenedioxy-1-(6,7-dimethoxy-3-phthalidyl)-1
• Hederix (free base)
• Vadebe
• Key-Tusscapine
• Narcotine (7CI, 8CI)
• 5-g]isoquinolin-5-yl)-,[s-(theta,s)]-3-dioxolo[4
• Phthalide, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-
• (S)-6,7-DIMETHOXY-3-((R)-4-METHOXY-6-METHYL-5,6,7,8-TETRAHYDRO-[1,3]DIOXOLO[4,5-G]ISOQUINOLIN-5-YL)-3H-ISOBENZOFURAN-1-ONE
• NOSCAPINE (NARCOTINE) NATURALLY OCCURRIN G O
• 1-alpha-Narcotine
• Detusso
• Noscapine (100 mg)
• Noscapine (Narcotine) base
• Noscapine (base and/or unspecified salts)
• Ecasil
• S(R*,S*)-6,7-DIMETHOXY-3-(5,6,7,8-TETRAHYDRO-4-METHOXY-6-METHYL-1,3-DIOXOLO[4,5-G]-ISOQUINOLIN-5-YL)-1(3H)-ISOBENZOFURANONE
• (S,R)-NOSCAPINE
• [S-(R*,S*)]-6,7-Dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-1(3H)-Isobenzofuranone
• ,2,3,4-tetrahydroisoquinaline
• Gnoscopine [dl-form]
• Terial
• 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1(3h)-isobenzofuranon
• dl-Narcotine [dl-form]
• 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, (3S)- (9CI)
• alpha-Narcotine
• nsc5366
• 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-1(3H)-isobenzofuranone, [S-(R*,S*)]
• Noscapine (500 mg)
• 5-g)isoquinolin-5-yl)-,(s-(r*,s*))-3-dioxolo(4
• Noscapal
• L-ALPHA-NARCOTINE

Noscapine Hydrochloride

CAS: 128-62-1, 219533-73-0, 912-60-7

Fórmula: C₂₂H₂₃NO₇·HCl

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 449.88

Ref: 3B-N0963

Noscapine

CAS: 128-62-1

Forma y color: Neat

Ref: 61-FOR1232.00

Noscapine 1.0 mg/ml in Acetonitrile

CAS: 128-62-1

Forma y color: Single Solution

Ref: 61-AMP1232.00-11

NOSCAPINE CRS

CAS: 128-62-1

NOSCAPINE CRS

Fórmula: C₂₂H₂₃NO₇

Forma y color: Added Modified

Peso molecular: 413.4205

Ref: 41-N1300000

Noscapine

CAS: 128-62-1

Alkaloids of opium and their derivatives, salts thereof, not elsewhere specified or included

Fórmula: C₂₂H₂₃NO₇

Forma y color: White Powder

Peso molecular: 413.14745

Ref: 45-1474504

Noscapine

CAS: 128-62-1

Fórmula: C₂₂H₂₃NO₇

Pureza: 97%

Forma y color: Solid

Peso molecular: 413.4205

Ref: IN-DA007O3K

Noscapine

CAS: 128-62-1

Fórmula: C₂₂H₂₃NO₇

Forma y color: White To Off-White Solid

Peso molecular: 413.43

Ref: 4Z-N-061012

Noscapine-13C-d3

CAS: 128-62-1

Fórmula: CC₂₁H₂₀D₃NO₇

Forma y color: White To Off-White Solid

Peso molecular: 417.44

Ref: 4Z-N-061001

Noscapine

CAS: 128-62-1

Forma y color: Neat

Ref: 86-MM1232.00

Noscapine

Producto controlado

CAS: 128-62-1

Fórmula: C₂₂H₂₃NO₇

Forma y color: Neat

Peso molecular: 413.42

Ref: 04-C15652400

Noscapine

CAS: 128-62-1

Applications Antitussive.
References Tsunoda, N., et al.: Xenobiotica, 9, 181 (1979), Dhalstroem, B., et al.: Eur. J. Clin. Pharmacol., 22, 535 (1982), Al-Yahya, M.A., et al.: Anal. Profiles Drug Subs., 11, 407 (1982),

Fórmula: C₂₂H₂₃NO₇

Forma y color: White

Peso molecular: 413.42

Ref: TR-N882000

Noscapine base

CAS: 128-62-1

Noscapine base is a natural alkaloid compound, which is derived from the opium poppy, Papaver somniferum. This bioactive compound modulates the microtubule assembly in cells, impacting the dynamic instability of microtubules, which is crucial in mitosis and cell division. The resultant modulation disrupts microtubule function, thereby exerting a cytostatic effect that hampers the proliferation of malignant cells.

Fórmula: C₂₂H₂₃NO₇

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 413.43 g/mol

Ref: 3D-FN09246