CAS 130405-40-2

(-)-galato de catequina

Descripción:

(-)-galato de catequina, con el número CAS 130405-40-2, es un compuesto polifenólico que se encuentra principalmente en varias plantas, particularmente en el té verde. Es un tipo de flavonoide, específicamente una catequina, conocida por sus propiedades antioxidantes. Este compuesto exhibe una estructura compleja que incluye un esqueleto de catequina con un grupo galato, lo que contribuye a su actividad biológica. (-)-galato de catequina es reconocido por sus posibles beneficios para la salud, incluidos efectos antiinflamatorios, anticancerígenos y cardioprotectores. Es soluble en agua y disolventes orgánicos, lo que lo hace versátil para diversas aplicaciones en alimentos, productos farmacéuticos y cosméticos. La estabilidad del compuesto puede verse influenciada por factores como el pH y la temperatura, y puede sufrir oxidación al estar expuesto al aire. La investigación continúa explorando sus mecanismos de acción y posibles usos terapéuticos, particularmente en el contexto de enfermedades crónicas. En general, (-)-galato de catequina es un compuesto importante en el campo de los productos naturales y las ciencias de la salud, reflejando el creciente interés en las sustancias derivadas de plantas para la promoción de la salud.

Fórmula: C₂₂H₁₈O₁₀

InChI: InChI=1S/C22H18O10/c23-11-6-14(25)12-8-19(32-22(30)10-4-16(27)20(29)17(28)5-10)21(31-18(12)7-11)9-1-2-13(24)15(26)3-9/h1-7,19,21,23-29H,8H2/t19-,21+/m1/s1

Clave InChI: InChIKey=LSHVYAFMTMFKBA-CTNGQTDRSA-N

SMILES: O(C(=O)C1=CC(O)=C(O)C(O)=C1)[C@H]2[C@@H](OC=3C(C2)=C(O)C=C(O)C3)C4=CC(O)=C(O)C=C4

Sinónimos:

• (-)-Catechin 3-O-gallate
• (-)-Catechin 3-gallate
• (2S,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate
• Benzoic acid, 3,4,5-trihydroxy-, (2S,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester
• Benzoic acid, 3,4,5-trihydroxy-, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester, (2S-trans)-
• Ccris 9303
• (-)-Catechin gallate
• Chorionic gonadotrophin chain β
• (-)-Catechin gallate ((-)-Catechin 3-gallate
• Choriogonadotropin subunit β
• (-)-Catechin gallate(CG)
• (-)-Catechin gallate, 98%, from Green tea
• Anti-HCG β, C-Terminal antibody produced in rabbit
• (2S,3R)-2-(3,4-DIHYDROXYPHENYL)-3,4-DIHYDRO-1(2H)-BENZOPYRAN-3,5,7-TRIOL 3-(3,4,5-TRIHYDROXYBENZOATE)
• (-)-CG
• 3,4,5-Trihydroxybenzoic Acid (2S,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl Ester
• BCatechin gallate
• ()-Catechin gallate,(2S,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate)
• ()-Catechin gallat
• ()-Catechin gallate, >=98%
• (2S,3R)-2-(3,4-Dihydroxyphenyl)-3-(3,4,5-trihydroxybenzoyloxy)-3,4-dihydro-2H-1-benzopyran-5,7-diol
• (2S,3R)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxychroMan-3-yl 3,4,5-trihydroxybenzoate
• 3,4,5-Trihydroxybenzoic acid [[(2S)-2β-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran]-3α-yl] ester
• Catechin gallate/(-)-Catechin gallate
• Catechin gallate CG (-)-Catechin gallate
• ANTI-CG antibody produced in mouse

(-) Catechin gallate

CAS: 130405-40-2

(-) Catechin gallate analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₂₂H₁₈O₁₀

Pureza: (HPLC) ≥98%

Forma y color: Powder

Peso molecular: 442.38

Ref: 11-0972S

Benzoic acid, 3,4,5-trihydroxy-, (2S,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester

CAS: 130405-40-2

Fórmula: C₂₂H₁₈O₁₀

Pureza: 98%

Forma y color: Solid

Peso molecular: 442.3723

Ref: IN-DA000UDI

(-)-Catechin gallate

CAS: 130405-40-2

(-)-Catechin gallate

Pureza: ≥95%

Peso molecular: 442.37g/mol

Ref: 54-BUP07425

Catechin gallate

CAS: 130405-40-2

Catechin gallate is a minor constituent in green tea catechins, it inhibits the activity of COX-1 and COX-2 enzymes. Catechin gallate (IC50=53 microM) shows cytotoxicity against the colorectal adenocarcinoma cell line HCT116, it also exhibits strong anti-proliferative and anti-inflammatory activities on pancreatic ductal adenocarcinoma (PDAC) cells. Catechin 3-gallate is a good inhibitor of maltase, with IC50 values of 62 uM, it inhibits both α-glucosidases and rabbit glycogen phosphorylase (GP) in vitro and in cell culture, would contribute to the protection or improvement of type 2 diabetes.

Fórmula: C₂₂H₁₈O₁₀

Pureza: 95%~99%

Peso molecular: 442.376

Ref: BP-BP0323

(-)-Catechin gallate

CAS: 130405-40-2

Fórmula: C₂₂H₁₈O₁₀

Peso molecular: 442.37

Ref: 7W-GK9244

(-)-Catechin gallate

CAS: 130405-40-2

(-)-Catechin gallate inhibits 6PGD, IDH, Beta-secretase, and fights chloroquine-sensitive/resistant Plasmodium falciparum.

Fórmula: C₂₂H₁₈O₁₀

Pureza: 97.74% - >99.99%

Forma y color: Solid

Peso molecular: 442.37

Ref: TM-T3682

(-)-catechin 3-gallate

CAS: 130405-40-2

Oxygen-heterocyclic compound

Fórmula: C₂₂H₁₈O₁₀

Pureza: ≥ 95.0 % (HPLC)

Forma y color: Powder

Peso molecular: 442.38

Ref: 5G-82497

(-)-Catechin Gallate

Producto controlado

CAS: 130405-40-2

Applications A major component of green tea, is a dual phosphoinositide-3-kinase/mTOR inhibitor.
References Van Aller, G., et al.: Biochem. Biophys. Res. Commun., 406, 194 (2011),

Fórmula: C₂₂H₁₈O₁₀

Forma y color: Neat

Peso molecular: 442.37

Ref: TR-C217510

Benzoic acid, 3,4,5-trihydroxy-, (2S,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester

CAS: 130405-40-2

Pureza: 98%

Peso molecular: 442.3760071

Ref: 10-F861685

(-)-Catechin gallate

CAS: 130405-40-2

(-)-Catechin gallate is a flavonoid that belongs to the group of polyphenols. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. (-)-Catechin gallate has shown protective effects on skin cells against ultraviolet-induced skin cancer and energy metabolism, as well as anti-inflammatory properties. This compound also inhibits the release of pro-inflammatory mediators by inhibiting P2Y receptors. (-)-Catechin gallate may have chemopreventive effects by blocking signaling pathways involved in colorectal adenocarcinoma, squamous carcinoma, and human serum.

Fórmula: C₂₂H₁₈O₁₀

Pureza: Min. 95%

Peso molecular: 442.37 g/mol

Ref: 3D-FC19836