CAS 13086-84-5

Fosfito de di-terc-butilo

Descripción:

Fosfito de di-terc-butilo es un compuesto organofosforado caracterizado por su grupo funcional fosfito, donde dos grupos tert-butilo están unidos a un átomo de fósforo. Típicamente es un líquido incoloro a amarillo pálido con un olor suave. Este compuesto es conocido por su papel como estabilizador y antioxidante en varios procesos químicos, particularmente en la producción de polímeros y plásticos. Fosfito de di-terc-butilo exhibe buena estabilidad térmica y puede actuar como agente reductor. Su estructura química contribuye a su volatilidad relativamente baja y solubilidad moderada en disolventes orgánicos. Además, es sensible a la humedad y puede hidrolizarse en presencia de agua, lo que lleva a la formación de ácidos fosfónicos. Las consideraciones de seguridad incluyen su potencial para causar irritación al contacto con la piel o los ojos, y debe manejarse con las precauciones adecuadas en un área bien ventilada. En general, Fosfito de di-terc-butilo es valorado en aplicaciones industriales por sus propiedades protectoras contra la degradación oxidativa.

Fórmula: C₈H₁₉O₃P

InChI: InChI=1/C8H19O3P/c1-7(2,3)10-12(9)11-8(4,5)6/h12H,1-6H3

Clave InChI: InChIKey=HLMXUWAUCZMWOG-UHFFFAOYSA-N

SMILES: O(C(C)(C)C)P(OC(C)(C)C)=O

Sinónimos:

• 2-Methyl-2-[(2-methylpropan-2-yl)oxyphosphonoyloxy]propane
• Di-Tert-Butoxy(Oxo)Phosphonium
• Di-Tert-Butyl Hydrogen Phosphite
• Di-Tert-Butyl Phosphonate
• Phosphonic acid, bis(1,1-dimethylethyl) ester
• Phosphonic acid, di-tert-butyl ester
• Phosphorous acid di-tert-butyl ester
• tert-Butyl phosphite ((C₄H₉O)₂P(OH))
• tert-Butyl phosphonate ((C₄H₉O)₂PH(O))
• Di-tert-butyl phosphite
• tert-Butyl phosphonate ((C4H9O)2PH(O))
• Di-tert-butyl phosphite 95%
• Einecs 235-996-8
• Ditertiarybutyl phosphite
• bis(1,1-dimethylethyl) phosphonate
• Di-tert-butyl phosphite ,97.5%
• Bis(2-methyl-2-propanyl) phosphonate

Di-tert-butyl Phosphonate

CAS: 13086-84-5

Fórmula: C₈H₁₉O₃P

Pureza: >98.0%(T)

Forma y color: Colorless to Almost colorless clear liquid

Peso molecular: 194.21

Ref: 3B-D5814

Di-tert-butyl phosphite, 95%

CAS: 13086-84-5

As a solvent, as an antioxidant, and as an intermediate

Fórmula: C₈H₁₈O₃P

Pureza: 95%

Forma y color: Clear colorless to yellow, Liquid

Peso molecular: 193.20

Ref: 02-030233

Phosphonic acid, bis(1,1-dimethylethyl) ester

CAS: 13086-84-5

Fórmula: C₈H₁₉O₃P

Pureza: 95%

Forma y color: Liquid

Peso molecular: 194.2084

Ref: IN-DA000V16

Di-tert-butyl phosphonate

CAS: 13086-84-5

Di-tert-butyl phosphonate

Fórmula: C₈H₁₉O₃P

Pureza: 99%

Forma y color: clear. almost colourless liquid

Peso molecular: 194.21g/mol

Ref: 54-OR75599

Di-tert-butylphosphite

CAS: 13086-84-5

Di-tert-butylphosphite is a phosphatase inhibitor that is used as a synthetic target in drug discovery. Di-tert-butylphosphite binds to the active site of phosphatases and prevents them from hydrolyzing the phosphate group from their substrates. This leads to an accumulation of the substrate and a decrease in enzymes, which inhibits protein synthesis. The sequence specificity of di-tert-butylphosphite has been shown by its affinity for tripeptides with hydrophobic amino acids at position P1 and P3. Di-tert-butylphosphite has been shown to inhibit cancer cell growth in vitro by binding to DNA and inhibiting RNA synthesis. It also inhibits farnesyl diphosphate synthase, which synthesizes the precursor for cholesterol biosynthesis, leading to decreased levels of cholesterol and reduced cell proliferation.

Fórmula: C₈H₁₉O₃P

Pureza: Min. 95 Area-%

Forma y color: Clear Liquid

Peso molecular: 194.21 g/mol

Ref: 3D-FD153843

Di-tert-butylphosphite

CAS: 13086-84-5

Fórmula: C₈H₁₉O₃P

Pureza: 95%

Forma y color: Liquid

Peso molecular: 194.211

Ref: 10-F044564

Di-tert-butyl Phosphite

Producto controlado

CAS: 13086-84-5

Applications Di-tert-butyl Phosphite is used as a reagent in the synthesis of chloromethyl di-tert-butyl phosphate, a key component in the formation of many phosphonoxymethyl pro-drugs. Also used as a reagent in the synthesis of L-phosphonophenylalanine (Ppa) derivatives suitable for solid phase peptide synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zheng, B., et al.: Org. Process Res. Dev., 18, 636 (2014); Chauhan, S.S., et al.: Tetrahedron Lett., 48, 4051 (2007)

Fórmula: C₈H₁₉O₃P

Forma y color: Neat

Peso molecular: 194.21

Ref: TR-D429515