CAS 13209-41-1
:(16α)-17,21-Dihidroxi-16-metilpregna-1,4,9(11)-trieno-3,20-diona
Descripción:
La sustancia química "(16α)-17,21-Dihidroxi-16-metilpregna-1,4,9(11)-trieno-3,20-diona," con el número CAS 13209-41-1, es un esteroide sintético que pertenece a la clase de los corticosteroides. Se caracteriza por una estructura esteroide compleja, que presenta múltiples grupos hidroxilo (-OH) que contribuyen a su actividad biológica. La presencia del grupo 16-metilo y los enlaces dobles específicos en el núcleo esteroide influyen en sus propiedades farmacológicas, incluyendo efectos antiinflamatorios e inmunosupresores. Este compuesto se estudia a menudo por sus posibles aplicaciones terapéuticas, particularmente en el tratamiento de diversas condiciones inflamatorias y trastornos relacionados con el sistema inmunológico. Su solubilidad, estabilidad e interacción con receptores biológicos son factores críticos que determinan su eficacia y perfil de seguridad. Al igual que muchos esteroides, puede presentar una variedad de efectos secundarios, lo que requiere una cuidadosa consideración en el uso clínico. En general, este compuesto ejemplifica la intrincada relación entre la estructura química y la función biológica en la química medicinal.
Fórmula:C22H28O4
InChI:InChI=1S/C22H28O4/c1-13-10-18-16-5-4-14-11-15(24)6-8-20(14,2)17(16)7-9-21(18,3)22(13,26)19(25)12-23/h6-8,11,13,16,18,23,26H,4-5,9-10,12H2,1-3H3/t13-,16-,18+,20+,21+,22+/m1/s1
Clave InChI:InChIKey=ZYTXTXAMMDTYDQ-DGEXFFLYSA-N
SMILES:C[C@@]12[C@]([C@]3(C(=CC1)[C@]4(C)C(CC3)=CC(=O)C=C4)[H])(C[C@@H](C)[C@@]2(C(CO)=O)O)[H]
Sinónimos:- (16Alpha)-17,21-Dihydroxy-16-Methylpregna-1,4,9(11)-Triene-3,20-Dione
- (16α)-17,21-Dihydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione
- 13209-41-1
- 17α,21-Dihydroxy-16α-methylpregna-1,4,9(11)-triene-3,20-dione
- Pregna-1,4,9(11)-triene-3,20-dione, 17,21-dihydroxy-16-methyl-, (16α)-
- Pregna-1,4,9(11)-triene-3,20-dione, 17,21-dihydroxy-16α-methyl-
- Vamorolone
- Vbp 15
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Encontrado 11 productos.
17,21-dihydroxy-16α-methylpregna-1,4,9(11)-triene-3,20-dione
CAS:Fórmula:C22H28O4Pureza:98%Forma y color:SolidPeso molecular:356.4553Vamorolone
CAS:Vamorolone (VBP15) is a steroid-like drug that treats muscular dystrophy with fewer side effects and inhibits NF-κB.Fórmula:C22H28O4Pureza:99.54%Forma y color:SolidPeso molecular:356.4616α-Methyl(d3)-9,11-dehydro Prednisolone
CAS:Producto controladoFórmula:C22D3H25O4Forma y color:NeatPeso molecular:359.4716a-Methyl-9,11-dehydro prednisolone - Bio-X ™
CAS:Producto controlado<p>This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.</p>Fórmula:C22H28O4Pureza:Min. 95%Forma y color:PowderPeso molecular:356.46 g/mol16a-Methyl-9,11-dehydro prednisolone
CAS:Producto controlado<p>Prednisolone is a steroid hormone that has been used for the treatment of inflammatory bowel disease. It has been shown to be effective in the treatment of bowel diseases and is also used as a replacement therapy for adrenal insufficiency. Prednisolone has an excellent safety profile and does not cause insulin resistance or weight gain, unlike some other steroids. It can be used to treat inflammatory diseases such as rheumatoid arthritis and psoriasis. The anti-inflammatory properties of prednisolone are due to its ability to bind to the mineralocorticoid receptor, which prevents the binding of cortisol. This blocks the conversion of cholesterol into pregnenolone, which is required for the production of glucocorticoids and mineralocorticoids. 16a-Methyl-9,11-dehydro prednisolone (16D) is a metabolite that can be found in blood plasma after oral administration of prednisolone. 16D binds</p>Fórmula:C22H28O4Pureza:Min. 97 Area-%Forma y color:PowderPeso molecular:356.46 g/mol
