CAS 13292-46-1

rifampicina

Descripción:

rifampicina, con el número CAS 13292-46-1, es un antibiótico semisintético que pertenece a la clase de las rifamicinas. Se utiliza principalmente para tratar infecciones bacterianas, particularmente la tuberculosis y la lepra, al inhibir la síntesis de ARN bacteriano. El compuesto presenta un color rojo-anaranjado y es conocido por su naturaleza lipofílica, lo que le permite penetrar eficazmente en las membranas celulares. rifampicina tiene una solubilidad relativamente baja en agua, pero es soluble en disolventes orgánicos como el etanol y la acetona. Su mecanismo de acción implica la unión a la subunidad beta de la ARN polimerasa bacteriana, impidiendo así la transcripción del ADN en ARN. Este antibiótico a menudo se administra en combinación con otros medicamentos para prevenir el desarrollo de resistencia. Además, rifampicina se metaboliza en el hígado y puede inducir enzimas del citocromo P450, afectando el metabolismo de otros medicamentos. Debido a sus potentes efectos y posibles efectos secundarios, incluida la hepatotoxicidad y las interacciones con otros medicamentos, es esencial un monitoreo cuidadoso durante el tratamiento.

Fórmula: C₄₃H₅₈N₄O₁₂

InChI: InChI=1/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,44-20?/t21?,23-,24-,25-,29+,34+,35-,39+,43+/m1/s1

Clave InChI: InChIKey=JQXXHWHPUNPDRT-ZNQWNCHJSA-N

SMILES: OC1=C2C3=C4O[C@@](C)(C3=O)O/C=C/[C@H](OC)[C@@H](C)[C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)\C=C\C=C(\C)/C(=O)NC(C(O)=C2C(O)=C4C)=C1C=NN5CCN(C)CC5

Sinónimos:

• (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-{(E)-[(4-methylpiperazin-1-yl)imino]methyl}-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate
• 2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan, rifamycin deriv.
• 2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione, 5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-[N-(4-methyl-1-piperazinyl)formimidoyl]-, 21-acetate
• 2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione, 5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,20,22-heptamethyl-8-[N-(4-methyl-1-piperazinyl)formimidoyl]-, 21-acetate
• 3-(((4-Methyl-1-piperazinyl)imino)-methyl)rifamycin
• 3-[(4-Methyl-1-piperazinyl)iminomethyl]rifamycin SV
• 5,6,9,17,19,21-Hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-[N-(4-methyl-1-piperazinyl)formimidoyl]-2,7-(epoxypentadeca[1,11,13]trienimino)-naphtho[2,1-b]furan-1,11(2H)-dione 21-acetate
• Abrifam
• Ba 41166/E
• Dipicin
• Eremfat
• Famcin
• L 5103 Lepetit
• Nih 10782
• Nsc 113926
• R-Cin
• R/Amp
• RIF
• Refampicin
• Rifa
• Rifacap
• Rifactine
• Rifadin
• Rifadin I.V.
• Rifadine
• Rifaldazine
• Rifaldin
• Rifamate
• Rifamicin AMP
• Rifampicin SV
• Rifampicina
• Rifampicine
• Rifampin
• Rifamycin AMP
• Rifamycin SV Sodium
• Rifamycin, 3-[[(4-methyl-1-piperazinyl)imino]methyl]-
• Rifamyzin 3-(4-Methyl-Piperazinyl)Iminomethyl
• Rifandin
• Rifaprodin
• Rifater
• Rifobac
• Rifodex
• Rifoldin
• Rifoldine
• Riforal
• Rimactan
• Rimactane
• Rimapen
• Rimycin
• Sinerdol

Rifampicin

CAS: 13292-46-1

Fórmula: C₄₃H₅₈N₄O₁₂

Pureza: >98.0%(T)

Forma y color: Orange to Amber to Dark red powder to crystal

Peso molecular: 822.95

Ref: 3B-R0079

Rifampin, Molecular Biology Reagent

CAS: 13292-46-1

Rifampin, 13292-46-1, also known as rifampicin, is a synthetic rifamycin antibiotic that works by inhibiting RNA and DNA synthesis. Learn more at Thermo Fisher Scientific.

Fórmula: C₄₃H₅₈N₄O₁₂

Forma y color: Red-brown, Crystals or powder or crystalline powder

Peso molecular: 822.95

Ref: 02-J60836

Rifampicin

CAS: 13292-46-1

Forma y color: Neat

Ref: 61-FOR0514.00

RIFAMPICIN CRS

CAS: 13292-46-1

RIFAMPICIN CRS

Fórmula: C₄₃H₅₈N₄O₁₂

Forma y color: Crystalline Powder. Dark Red. Brown. Powder.

Peso molecular: 822.9402

Ref: 41-R0700000

Rifampin

CAS: 13292-46-1

Antibiotics nesoi

Fórmula: C₄₃H₅₈N₄O₁₂

Forma y color: Reddish-Brown Powder

Peso molecular: 822.40512

Ref: 45-1604009

Rifampicin

CAS: 13292-46-1

Rifampicin (Rifamycin AMP) is a broad-spectrum antibiotic with strong antibacterial effect against Mycobacterium tuberculosis. Cost effective and quality assured.

Fórmula: C₄₃H₅₈N₄O₁₂

Pureza: 96.7% - 98.52%

Forma y color: Red To Orange Platelets From Acetone Solid

Peso molecular: 822.94

Ref: TM-T0681

3-(((4-Methyl-1-piperazinyl)imino)-methyl)rifamycin

CAS: 13292-46-1

Fórmula: C₄₃H₅₈N₄O₁₂

Pureza: 96%

Forma y color: Solid

Peso molecular: 822.9402

Ref: IN-DA00397J

Rifampicin

CAS: 13292-46-1

Rifampicin

Pureza: ≥95%

Peso molecular: 822.94g/mol

Ref: 54-BUP18382

Rifampicin

CAS: 13292-46-1

Fórmula: C₄₃H₅₈N₄O₁₂

Pureza: 97.0 - 102.0 % (dried basis)

Forma y color: Red to brown crystalline powder

Peso molecular: 822.94

Ref: 7W-GA1853

Rifampicin

CAS: 13292-46-1

Rifampicin

Fórmula: C₄₃H₅₈N₄O₁₂

Pureza: 95%

Forma y color: dark red powder

Peso molecular: 822.94022g/mol

Ref: 54-BIR0146

Rifampicin

CAS: 13292-46-1

Fórmula: C₄₃H₅₈N₄O₁₂

Forma y color: Orange Red Solid

Peso molecular: 822.95

Ref: 4Z-R-234

Rifampicin-d4

CAS: 13292-46-1

Fórmula: C₄₃H₅₄D₄N₄O₁₂

Forma y color: Dark Orange Solid

Peso molecular: 826.98

Ref: 4Z-R-236

Rifampicin-d11 (4-methyl-d3-1-piperazinyl-d8)

CAS: 13292-46-1

Pureza: 98 atom % D

Peso molecular: 833.97

Ref: 3U-D8131

Rifampicin

Producto controlado

CAS: 13292-46-1

Fórmula: C₄₃H₅₈N₄O₁₂

Forma y color: Neat

Peso molecular: 822.94

Ref: 86-MM0514.00

Rifampicin

Producto controlado

CAS: 13292-46-1

Fórmula: C₄₃H₅₈N₄O₁₂

Forma y color: Neat

Peso molecular: 822.94

Ref: 04-C16814500

Rifampicin-13C-d3

CAS: 13292-46-1

Fórmula: C₄₃H₅₅N₄O₁₂D₃

Peso molecular: 826.97

Ref: 4Z-R-235

Rifampicin

Producto controlado

CAS: 13292-46-1

Applications Semisynthetic antibiotic. Antibacerial (tuberculostatic).
References Furesz, et al.: Antibiot. Chemother., 16, 316 (1970), Gallo, G.G., et al.: Anal. Profiles Drug Subs., 5, 467 (1976),

Fórmula: C₄₃H₅₈N₄O₁₂

Forma y color: Dark Red

Peso molecular: 822.94

Ref: TR-R508000

Rifampicin

CAS: 13292-46-1

Fórmula: C₄₃H₅₈N₄O₁₂

Peso molecular: 822.95

Ref: ST-EA-CP-R33000

Rifampicin-d4

Producto controlado

CAS: 13292-46-1

Fórmula: C₄₃D₄H₅₄N₄O₁₂

Forma y color: Neat

Peso molecular: 826.965

Ref: TR-R508043

Rifampicin-d8

Producto controlado

CAS: 13292-46-1

Fórmula: C₄₃D₈H₅₀N₄O₁₂

Forma y color: Neat

Peso molecular: 830.99

Ref: TR-R508003

Rifampicin

CAS: 13292-46-1

Inhibitor of RNA synthesis

Fórmula: C₄₃H₅₈N₄O₁₂

Pureza: Min. 95%

Forma y color: Orange Red Powder

Peso molecular: 822.94 g/mol

Ref: 3D-AR11351

Rifampicin (RFP) (Rifampin), 97-102%

CAS: 13292-46-1

Fórmula: C₄₃H₅₈N₄O₁₂

Pureza: 97-102%

Forma y color: A brick red to reddish brown, Crystalline powder

Peso molecular: 822.95

Ref: SR-12310

Rifampicin (RFP) (Rifampin) for cell culture, 97-102%, Endotoxin (BET) 0.05EU/mg

CAS: 13292-46-1

Fórmula: C₄₃H₅₈N₄O₁₂

Pureza: 97-102%

Forma y color: A brick red to reddish brown, Crystalline powder

Peso molecular: 822.95

Ref: SR-46143

Rifampicin, Antibiotic for Culture Media Use Only

CAS: 13292-46-1

Rifampicin is a drug that inhibits protein synthesis in bacteria and is used to treat tuberculosis. Rifampicin binds to the beta subunit of the bacterial RNA polymerase, inhibiting transcription and translation. It has been shown to inhibit the acetylcholine receptor function in rats, which may be related to its antituberculosis activity. Histopathological studies have shown that rifampicin inhibits the growth of human tumors in mice, including lung cancer, breast cancer, and leukemia. The drug is also being studied for its potential use in treating Alzheimer's disease. The pharmacokinetics and oral bioavailability of rifampicin have been studied and Rifampicin has been shown to be an effective anti-tuberculosis drug.

Fórmula: C₄₃H₅₈N₄O₁₂

Pureza: Min. 90.0 Area-%

Peso molecular: 822.94 g/mol

Ref: 3D-R-6000

RIFAMPICIN RS

CAS: 13292-46-1

RIFAMPICIN RS

Fórmula: C₄₃H₅₈N₄O₁₂

Peso molecular: 822.9402

Ref: 41-ICRS0409