CAS 134-63-4
:Clorhidrato de (-)-Lobelina
Descripción:
Clorhidrato de (-)-Lobelina es un compuesto químico que se conoce principalmente por su uso en farmacología y como un posible agente terapéutico. Es un alcaloide derivado de la planta Lobelia inflata, comúnmente conocida como tabaco indio. Este compuesto exhibe una variedad de actividades biológicas, incluidos efectos en el sistema nervioso central, donde puede actuar como un estimulante o un depresor dependiendo de la dosis y el contexto. Clorhidrato de (-)-Lobelina se caracteriza por su naturaleza quiral, con el "(-)" que indica su estereoequilibrio específico, que es crucial para su actividad biológica. La forma de sal hidrocloruro mejora su solubilidad en agua, haciéndola más adecuada para aplicaciones farmacéuticas. Además de sus posibles usos terapéuticos, se ha estudiado el (-)-Lobelina por sus efectos sobre la adicción a la nicotina y como un estimulante respiratorio. Sin embargo, su uso está sujeto a un escrutinio regulatorio debido a preocupaciones sobre la seguridad y la eficacia. En general, Clorhidrato de (-)-Lobelina es un compuesto de interés tanto en química medicinal como en farmacología, con investigaciones en curso sobre sus diversas aplicaciones.
Fórmula:C22H27NO2·ClH
InChI:InChI=1S/C22H27NO2.ClH/c1-23-19(15-21(24)17-9-4-2-5-10-17)13-8-14-20(23)16-22(25)18-11-6-3-7-12-18;/h2-7,9-12,19-21,24H,8,13-16H2,1H3;1H/t19-,20+,21-;/m0./s1
Clave InChI:InChIKey=MKMYPTLXLWOUSO-NFQNBQCWSA-N
SMILES:C([C@H](O)C1=CC=CC=C1)[C@H]2N(C)[C@@H](CC(=O)C3=CC=CC=C3)CCC2.Cl
Sinónimos:- (-)-α-Lobeline hydrochloride
- 2-((2R,6S)-6-((S)-2-Hydroxy-2-Phenylethyl)-1-Methylpiperidin-2-Yl)-1-Phenylethanone Hydrochloride
- 2-(6-(2-Hydroxy-2-Phenethyl)-1-Methyl-2-Piperidyl)Acetophenone Hydrochloride
- 2-[6-(2-Hydroxy-2-Phenylethyl)-1-Methylpiperidin-2-Yl]-1-Phenylethanone Hydrochloride (1:1)
- 2-{(2R,6S)-6-[(2R)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone hydrochloride
- 2-{(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone
- 2-{(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone hydrochloride (1:1)
- Butane-1,4-Diyl Dimethanesulfonate
- Ethanone, 2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenyl-, hydrochloride
- Ethanone, 2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenyl-, hydrochloride (1:1)
- Ethanone, 2-[6-(2-hydroxy-2-phenylethyl)-1-methyl-2-piperidinyl]-1-phenyl-, hydrochloride, [2R-[2α,6α(S*)]]-
- Lobelin hydrochloride
- Lobeline HCL
- Lobron
- Vuf 10751
- Zoolobelin
- alpha-Lobeline hydrochloride
- (-)-Lobeline hydrochloride
- Lobeline hydrochloride
- Lobeline, hydrochloride
- ALPHA-LOBELIN HCL
- 2-(6-(beta-hydroxyphenethyl)-1-methyl-2-piperidyl)-acetophenonhydrochlor
- A-LOBELINE HCL
- 2-(6-[2-HYDROXY-2-PHENYLETHYL]-1-METHYL-2-PIPERIDINYL)-1-PHENYLETHANONE HYDROCHLORIDE
- 2-(6-[2-Hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl)-1-phenylethanone, L-Lobeline, Hydrochloride
- LOBELINE HCL, A-
- 2-[6-(.beta.-hydroxyphenethyl)-1-methyl-2-piperidyl]-,hydrochloride,(-)-Acetophenone
- 2-[(2r,6s)-6-[(2s)-2-hydroxy-2-phenyl-ethyl]-1-methyl-2-piperidyl]-1-phenyl-ethanone hydrochloride
- 2-[6-(2-HYDROXY-2-PHENETHYL)-1-METHYL-2-PIPERIDYL]ACETOPHENONE HCL
- Apolipoprotein B (LDL), Sheep anti-Human, Guinea pig, Swine (NO X w/Bovine, Horse, Dog, Cat, Rabbit, Chicken, Goat, Mouse, Rat)
- Lobelinhydrochloride
- L-LOBELINE HYDROCHLORIDE
- [2-[(2R,6S)-6-[(2S)-2-HYDROXYPHENETHYL]]-1-METHYL-2-PIPERIDYL]ACETOPHENONE HYDROCHLORIDE
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Encontrado 11 productos.
Lobeline hydrochloride
CAS:Lobeline hydrochloride (α-Lobeline hydrochloride) is a nicotinic receptor agonist, acting as an effective antagonist at both α4β2 and α3β2 neuronal nicotinicFórmula:C22H27NO2·HClPureza:99.31% - 99.43%Forma y color:Rosettes Of Slender Needles From Alc White To Off-White SolidPeso molecular:373.92Lobeline HCl
CAS:Fórmula:C22H27NO2·HClForma y color:White To Off-White SolidPeso molecular:337.46 36.46(-)-Lobeline hydrochloride
CAS:Fórmula:C22H27NO2·HClPureza:≥ 97.0%Forma y color:White to off-white powderPeso molecular:373.92Lobeline Hydrochloride
CAS:Producto controladoFórmula:C22H27NO2·ClHForma y color:NeatPeso molecular:373.92a-Lobeline hydrochloride
CAS:a-Lobeline hydrochloride is an alkaloid-based compound, which is primarily derived from the Lobelia plant species. It functions as a nicotinic acetylcholine receptor antagonist and dopamine transporter inhibitor, interacting with the central nervous system to modulate neurotransmitter activities. This compound has historically been explored for its potential in nicotine addiction treatment due to its ability to inhibit the reuptake of dopamine, thereby influencing reward pathways associated with addiction.
Fórmula:C22H28ClNO2Pureza:Min. 95%Forma y color:White/Off-White SolidPeso molecular:373.92 g/mol2-(6-(2-Hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethanone hydrochloride
CAS:Fórmula:C22H28ClNO2Pureza:98%Peso molecular:373.92alpha-Lobeline Hydrochcloride
CAS:Producto controladoApplications A neuronal nicotinic acetylcholine receptor agonist. A CNS stimulant.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Damaj, M.I., et al.: J. Pharmacol. Exp. Ther., 282, 410 (1997), Toth, P.T., et al.: Eur. J. Pharmacol., 363, 75 (1998), Flammia, D., et al.: J. Med. Chem., 42, 3726 (1999), Dwoskin, P.A., et al.: Biochem. Pharmacol., 63, 89 (2002),Fórmula:C22H27NO2·ClHForma y color:NeatPeso molecular:373.92
