CAS 134-63-4

Clorhidrato de (-)-Lobelina

Descripción:

Clorhidrato de (-)-Lobelina es un compuesto químico que se conoce principalmente por su uso en farmacología y como un posible agente terapéutico. Es un alcaloide derivado de la planta Lobelia inflata, comúnmente conocida como tabaco indio. Este compuesto exhibe una variedad de actividades biológicas, incluidos efectos en el sistema nervioso central, donde puede actuar como un estimulante o un depresor dependiendo de la dosis y el contexto. Clorhidrato de (-)-Lobelina se caracteriza por su naturaleza quiral, con el "(-)" que indica su estereoequilibrio específico, que es crucial para su actividad biológica. La forma de sal hidrocloruro mejora su solubilidad en agua, haciéndola más adecuada para aplicaciones farmacéuticas. Además de sus posibles usos terapéuticos, se ha estudiado el (-)-Lobelina por sus efectos sobre la adicción a la nicotina y como un estimulante respiratorio. Sin embargo, su uso está sujeto a un escrutinio regulatorio debido a preocupaciones sobre la seguridad y la eficacia. En general, Clorhidrato de (-)-Lobelina es un compuesto de interés tanto en química medicinal como en farmacología, con investigaciones en curso sobre sus diversas aplicaciones.

Fórmula: C₂₂H₂₇NO₂·ClH

InChI: InChI=1S/C22H27NO2.ClH/c1-23-19(15-21(24)17-9-4-2-5-10-17)13-8-14-20(23)16-22(25)18-11-6-3-7-12-18;/h2-7,9-12,19-21,24H,8,13-16H2,1H3;1H/t19-,20+,21-;/m0./s1

Clave InChI: InChIKey=MKMYPTLXLWOUSO-NFQNBQCWSA-N

SMILES: C([C@H](O)C1=CC=CC=C1)[C@H]2N(C)[C@@H](CC(=O)C3=CC=CC=C3)CCC2.Cl

Sinónimos:

• (-)-α-Lobeline hydrochloride
• 2-((2R,6S)-6-((S)-2-Hydroxy-2-Phenylethyl)-1-Methylpiperidin-2-Yl)-1-Phenylethanone Hydrochloride
• 2-(6-(2-Hydroxy-2-Phenethyl)-1-Methyl-2-Piperidyl)Acetophenone Hydrochloride
• 2-[6-(2-Hydroxy-2-Phenylethyl)-1-Methylpiperidin-2-Yl]-1-Phenylethanone Hydrochloride (1:1)
• 2-{(2R,6S)-6-[(2R)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone hydrochloride
• 2-{(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone
• 2-{(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone hydrochloride (1:1)
• Butane-1,4-Diyl Dimethanesulfonate
• Ethanone, 2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenyl-, hydrochloride
• Ethanone, 2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenyl-, hydrochloride (1:1)
• Ethanone, 2-[6-(2-hydroxy-2-phenylethyl)-1-methyl-2-piperidinyl]-1-phenyl-, hydrochloride, [2R-[2α,6α(S*)]]-
• Lobelin hydrochloride
• Lobeline HCL
• Lobron
• Vuf 10751
• Zoolobelin
• alpha-Lobeline hydrochloride
• (-)-Lobeline hydrochloride
• Lobeline hydrochloride
• Lobeline, hydrochloride
• ALPHA-LOBELIN HCL
• 2-(6-(beta-hydroxyphenethyl)-1-methyl-2-piperidyl)-acetophenonhydrochlor
• A-LOBELINE HCL
• 2-(6-[2-HYDROXY-2-PHENYLETHYL]-1-METHYL-2-PIPERIDINYL)-1-PHENYLETHANONE HYDROCHLORIDE
• 2-(6-[2-Hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl)-1-phenylethanone, L-Lobeline, Hydrochloride
• LOBELINE HCL, A-
• 2-[6-(.beta.-hydroxyphenethyl)-1-methyl-2-piperidyl]-,hydrochloride,(-)-Acetophenone
• 2-[(2r,6s)-6-[(2s)-2-hydroxy-2-phenyl-ethyl]-1-methyl-2-piperidyl]-1-phenyl-ethanone hydrochloride
• 2-[6-(2-HYDROXY-2-PHENETHYL)-1-METHYL-2-PIPERIDYL]ACETOPHENONE HCL
• Apolipoprotein B (LDL), Sheep anti-Human, Guinea pig, Swine (NO X w/Bovine, Horse, Dog, Cat, Rabbit, Chicken, Goat, Mouse, Rat)
• Lobelinhydrochloride
• L-LOBELINE HYDROCHLORIDE
• [2-[(2R,6S)-6-[(2S)-2-HYDROXYPHENETHYL]]-1-METHYL-2-PIPERIDYL]ACETOPHENONE HYDROCHLORIDE

LOBELINE HYDROCHLORIDE CRS

CAS: 134-63-4

LOBELINE HYDROCHLORIDE CRS

Fórmula: C₆H₁₄O₆S₂

Peso molecular: 246.3018

Ref: 41-Y0000112

Lobeline hydrochloride

CAS: 134-63-4

Fórmula: C₂₂H₂₈ClNO₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 373.9162

Ref: IN-DA003VFX

Lobeline hydrochloride

CAS: 134-63-4

Lobeline hydrochloride (α-Lobeline hydrochloride) is a nicotinic receptor agonist, acting as an effective antagonist at both α4β2 and α3β2 neuronal nicotinic

Fórmula: C₂₂H₂₇NO₂·HCl

Pureza: 99.31% - 99.43%

Forma y color: Rosettes Of Slender Needles From Alc White To Off-White Solid

Peso molecular: 373.92

Ref: TM-T0268

Lobeline HCl

CAS: 134-63-4

Fórmula: C₂₂H₂₇NO₂·HCl

Forma y color: White To Off-White Solid

Peso molecular: 337.46 36.46

Ref: 4Z-L-101001

Lobeline hydrochloride

CAS: 134-63-4

Lobeline hydrochloride

Pureza: ≥98%

Peso molecular: 373.92g/mol

Ref: 54-BUP16097

(-)-Lobeline hydrochloride

CAS: 134-63-4

Fórmula: C₂₂H₂₇NO₂·HCl

Pureza: ≥ 97.0%

Forma y color: White to off-white powder

Peso molecular: 373.92

Ref: 7W-GK1502

Lobelin hydrochloride

CAS: 134-63-4

Fórmula: C₂₂H₂₈ClNO₂

Pureza: 95%~99%

Peso molecular: 373.921

Ref: BP-BP4246

Lobeline Hydrochloride

Producto controlado

CAS: 134-63-4

Fórmula: C₂₂H₂₇NO₂·ClH

Forma y color: Neat

Peso molecular: 373.92

Ref: 86-MM3423.00

a-Lobeline hydrochloride

CAS: 134-63-4

a-Lobeline hydrochloride is an alkaloid-based compound, which is primarily derived from the Lobelia plant species. It functions as a nicotinic acetylcholine receptor antagonist and dopamine transporter inhibitor, interacting with the central nervous system to modulate neurotransmitter activities. This compound has historically been explored for its potential in nicotine addiction treatment due to its ability to inhibit the reuptake of dopamine, thereby influencing reward pathways associated with addiction.

Fórmula: C₂₂H₂₈ClNO₂

Pureza: Min. 95%

Forma y color: White/Off-White Solid

Peso molecular: 373.92 g/mol

Ref: 3D-FL24916

2-(6-(2-Hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethanone hydrochloride

CAS: 134-63-4

Fórmula: C₂₂H₂₈ClNO₂

Pureza: 98%

Peso molecular: 373.92

Ref: 10-F222379

α-Lobeline Hydrochcloride

Producto controlado

CAS: 134-63-4

Applications A neuronal nicotinic acetylcholine receptor agonist. A CNS stimulant.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Damaj, M.I., et al.: J. Pharmacol. Exp. Ther., 282, 410 (1997), Toth, P.T., et al.: Eur. J. Pharmacol., 363, 75 (1998), Flammia, D., et al.: J. Med. Chem., 42, 3726 (1999), Dwoskin, P.A., et al.: Biochem. Pharmacol., 63, 89 (2002),

Fórmula: C₂₂H₂₇NO₂·ClH

Forma y color: Neat

Peso molecular: 373.92

Ref: TR-L469350