CAS 134523-00-5
:Atorvastatina
Descripción:
Atorvastatina es un agente sintético para reducir lípidos que pertenece a la clase de las estatinas, utilizado principalmente para manejar la hiperlipidemia y reducir el riesgo de enfermedades cardiovasculares. Su mecanismo de acción implica la inhibición de la HMG-CoA reductasa, una enzima crítica en la vía de biosíntesis del colesterol, lo que lleva a niveles disminuidos de lipoproteínas de baja densidad (LDL) y colesterol total en el torrente sanguíneo. Atorvastatina se caracteriza por su fórmula molecular, que incluye átomos de carbono, hidrógeno, nitrógeno y oxígeno, reflejando su estructura compleja. El compuesto se administra típicamente por vía oral y exhibe buena biodisponibilidad. Se metaboliza principalmente en el hígado, con una porción significativa que sufre metabolismo de primer paso. Los efectos secundarios comunes pueden incluir dolor muscular, alteraciones en las enzimas hepáticas y trastornos gastrointestinales. Atorvastatina a menudo se prescribe junto con modificaciones en el estilo de vida, como dieta y ejercicio, para mejorar su eficacia en la reducción de los niveles de colesterol. Sus beneficios terapéuticos, junto con los riesgos potenciales, requieren un monitoreo cuidadoso por parte de los profesionales de la salud durante el tratamiento.
Fórmula:C33H35FN2O5
InChI:InChI=1S/C33H35FN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40)/t26-,27-/m1/s1
Clave InChI:InChIKey=XUKUURHRXDUEBC-KAYWLYCHSA-N
SMILES:C(NC1=CC=CC=C1)(=O)C=2C(=C(N(CC[C@H](C[C@H](CC(O)=O)O)O)C2C(C)C)C3=CC=C(F)C=C3)C4=CC=CC=C4
Sinónimos:- (3R,5R)-7-[2-(4-Fluorophenyl)-3-Phenyl-4-(Phenylcarbamoyl)-5-Propan-2-Yl-Pyrrol-1-Yl]-3,5-Dihydroxy-Heptanoic Acid
- (3R,5R)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-phenylcarbamoylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid
- (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid
- (3S,5S)-7-[2-(4-Fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid
- (3S,5S)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid
- (βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid
- (βR,δR)-2-(p-Fluorophenyl)-β,δ-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoic acid
- 1H-Pyrrole-1-Heptanoic Acid
- 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, (βR,δR)-
- 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, (βR,δR)-rel-
- 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, [R-(R*,R*)]-
- 1H-pyrrole-1-heptanoate, 3-benzoyl-5-(4-fluorophenyl)-β,δ-dihydroxy-2-(1-methylethyl)-4-phenyl-, calcium salt, (betaR,deltaR)- (1:1)
- Atavastatin
- Atofast
- Atorcor
- Atorfit 20
- Atorin
- Atoris
- Atorvastatin Acid
- Atorvox
- Atrox
- Cardyl
- Lipilou
- Lipinon
- Statofilm
- calcium bis{(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate}
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Encontrado 9 productos.
Atorvastatin Calcium Salt Trihydrate
CAS:Fórmula:C66H68CaF2N4O10·3H2OPureza:>98.0%(HPLC)(N)Forma y color:White to Almost white powder to crystalPeso molecular:1,209.41(3R,5R)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-phenylcarbamoylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid
CAS:Fórmula:C33H35FN2O5Pureza:98%Forma y color:SolidPeso molecular:558.6398Atorvastatin
CAS:Fórmula:C33H35FN2O5Pureza:≥ 98%Forma y color:White to off-white crystalline powderPeso molecular:558.64Des-(N-Phenyl)Carbamoyl Atorvastatin Calcium Salt
CAS:Producto controladoFórmula:(C26H29FNO4)•CaForma y color:NeatPeso molecular:2(438.52) + (40.08)Atorvastatin acid
CAS:Atorvastatin acid is a pharmaceutical compound belonging to the class of statins, which is a synthetic derivative of fungal metabolites. It functions as an HMG-CoA reductase inhibitor, playing a critical role in the cholesterol biosynthesis pathway. By inhibiting this key enzyme, atorvastatin acid effectively reduces the conversion of HMG-CoA to mevalonate, a precursor of cholesterol, thus lowering overall cholesterol levels in the bloodstream.Fórmula:C33H35FN2O5Pureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:558.64 g/molAtorvastatin
CAS:Orally active atorvastatin inhibits HMG-CoA reductase, lowers lipids, hinders SV-SMC cell growth, and can up thrombotic risk with clopidogrel.Fórmula:C33H35FN2O5Pureza:99.37% - 99.69%Forma y color:SolidPeso molecular:558.64(3R,5R)-7-(2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid
CAS:Fórmula:C33H35FN2O5Pureza:98.0%Forma y color:Solid, White powderPeso molecular:558.653-Fluoro Atorvastatin Sodium Salt-d5
CAS:Producto controladoFórmula:C33D5H29FN2NaO5Forma y color:NeatPeso molecular:585.6523-Fluoro Atorvastatin Sodium Salt
CAS:Producto controlado<p>Applications 3-Fluoro Atorvastatin Sodium Salt is an impurity of Atorvastatin (A791750, Ca Salt); a selective, competitive HMG-CoA reductase inhibitor and the only drug in its class specifically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Fórmula:C33H34FN2NaO5Forma y color:NeatPeso molecular:580.62
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