CAS 1346168-57-7

CEP-33779

CAS: 1346168-57-7

CEP-33779 is a small-molecule inhibitor designed to target the Janus kinase 2 (JAK2) enzyme, which is a crucial component in the JAK-STAT signaling pathway originating from pro-inflammatory cytokine and growth factor receptors. Derived through sophisticated medicinal chemistry and pharmacological exploration, CEP-33779 functions by selectively inhibiting JAK2 activity. This inhibition is achieved by binding to the ATP-binding pocket of the JAK2 enzyme, thereby blocking the phosphorylation and subsequent activation of STAT proteins, which are essential for the transcription of genes involved in inflammation and tumor proliferation.

Fórmula: C₂₄H₂₆N₆O₂S

Pureza: Min. 95%

Peso molecular: 462.6 g/mol

Ref: 3D-WDC16857