CAS 13553-79-2
:Rifamicina S
Descripción:
Rifamicina S es un antibiótico natural que pertenece a la clase de las rifamicinas, derivado principalmente de la bacteria Amycolatopsis rifamycinica. Se caracteriza por su compleja estructura macrocíclica, que incluye un núcleo naftalénico y un cromóforo rifamicina característico. Este compuesto exhibe una potente actividad antibacteriana, particularmente contra Mycobacterium tuberculosis, lo que lo hace significativo en el tratamiento de la tuberculosis y otras infecciones bacterianas. Rifamicina S actúa inhibiendo la síntesis de ARN bacteriano mediante la unión a la ARN polimerasa dependiente de ADN, evitando así la transcripción. La sustancia se administra típicamente en sus formas derivadas, como la rifampicina, que mejora sus propiedades farmacológicas. Además de su eficacia antimicrobiana, Rifamicina S tiene un perfil de toxicidad relativamente bajo, aunque puede causar efectos secundarios como elevación de enzimas hepáticas y reacciones de hipersensibilidad en algunos pacientes. Sus características de solubilidad varían, influyendo en su formulación y métodos de entrega en entornos clínicos. En general, Rifamicina S es un compuesto crucial en el campo de la terapia antimicrobiana, particularmente para cepas bacterianas resistentes.
Fórmula:C37H45NO12
InChI:InChI=1/C37H45NO12/c1-16-11-10-12-17(2)36(46)38-23-15-24(40)26-27(32(23)44)31(43)21(6)34-28(26)35(45)37(8,50-34)48-14-13-25(47-9)18(3)33(49-22(7)39)20(5)30(42)19(4)29(16)41/h10-16,18-20,25,29-30,33,41-43H,1-9H3,(H,38,46)/b11-10+,14-13+,17-12-/t16-,18+,19+,20+,25-,29-,30+,33+,37-/m0/s1
Clave InChI:InChIKey=BTVYFIMKUHNOBZ-ODRIEIDWSA-N
SMILES:O=C1C=2C3=C4C(=O)C(=CC3=O)NC(=O)\C(\C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2C(C)=C4O
Sinónimos:- (14E,24E)-5,17,19-trihydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,6,9,11-tetraoxo-1,2,6,9-tetrahydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate
- (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-5,17,19-trihydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,6,9,11-tetraoxo-1,2,6,9-tetrahydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate
- 1,4-Dideoxy-1,4-dihydro-1,4-dioxo-rifamycin
- 1,4-Dideoxy-1,4-dihydro-1,4-dioxorifamycin
- 2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,6,9,11(2H)-tetrone, 5,17,19,21-tetrahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-, 21-acetate
- 2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan, rifamycin deriv.
- 5,17,19-Trihydroxy-23-Methoxy-2,4,12,16,18,20,22-Heptamethyl-1,6,9,11-Tetraoxo-1,2,6,9-Tetrahydro-2,7-(Epoxypentadeca[1,11,13]Trienoimino)Naphtho[2,1-B]Furan-21-Yl Acetate
- Brn 0604802
- Nci 144-130
- Nsc 144130
- Rifamycin, 1,4-dideoxy-1,4-dihydro-1,4-dioxo-
- Rifomycin S
- Unii-Pi53N820Jv
- RIFAMYCIN S
- Rifamycin S CRS
- rifamycin
- RIFAMPICIN S
- 2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,6,9,11(2h)-tetron
- 2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,6,9,11(2H)-tetrone, 5,17,19,21-tetrahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-, 21-acetate (7CI,8CI)
- Rifamycin Impurity 2(Rifamycin EP Impurity B)（Rifamycin S)
- Rifaximin impurity E (EP)
- Rifaximin EP Impurity E (Rifamycin S)
- Rifamycin EP Impurity B
- 5,17,19,21-tetrahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-21-aceta
- 100722
- rifomycins
- nci144-130
- 5,17,19,21-Tetrahydroxy-23-Methoxy-2,4,12,16,18,20,22-heptaMethyl-2,7-(epoxypentadeca[1,11,13]trieniMino)naphtho[2,1-b]furan-1,6,9,11(2H)-tetrone 21-Acetate
- Rifamycin S USP/EP/BP
- Rifaximin Impurity 5 (Rifaximin EP Impurity E)
- 4-dideoxy-1,4-dihydro-1,4-dioxo-rifamycin
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Encontrado 12 productos.
Rifamycin S
CAS:Fórmula:C37H45NO12Pureza:>98.0%(HPLC)Forma y color:Light yellow to Brown powder to crystalPeso molecular:695.762,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,6,9,11(2H)-tetrone, 5,17,19,21-tetrahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-, 21-acetate (7CI,8CI)
CAS:Fórmula:C37H45NO12Pureza:97%Forma y color:SolidPeso molecular:695.7527Ref: IN-DA0035KK
1g26,00€5g35,00€15g65,00€1kg683,00€25g74,00€5kgA consultar100g190,00€10kgA consultarRifaximin EP Impurity E (Rifamycin S)
CAS:Fórmula:C37H45NO12Forma y color:Orange SolidPeso molecular:695.76Rifamycin S
CAS:Rifamycin S is a potent DNA-dependent RNA polymerase inhibitor,is a quinone and an antibiotic agnet against Gram-positive bacteriaFórmula:C37H45NO12Pureza:98.74%Forma y color:Yellow Orange Crystalline PowderPeso molecular:695.75Rifamycin S
CAS:Producto controlado<p>Impurity Rifaximin EP Impurity E<br>Applications Rifamycin S (Rifaximin EP Impurity E) is a semi-synthetic antibiotic.<br>References Li, J., et al.: Bioorg. Med. Chem. Lett., 17, 5510 (2007), Patil, R., et al.: J. Pure & App. Microbiol., 2, 211 (2008),<br></p>Fórmula:C37H45NO12Forma y color:NeatPeso molecular:695.75Rifamycin S
CAS:<p>Rifamycin S is a rifamycin that is used as a model system to study the activity of other drugs. It is also used to treat infectious diseases, such as bowel disease, by inhibiting bacterial growth. Rifamycin S has been shown to have drug interactions with other drugs and can cause acute toxicities in the form of multivariate logistic regression. It has also been shown to inhibit the enzymatic inactivation of a number of antibiotics, such as methicillin and penicillin, which may be due to its ability to bind DNA templates. Rifamycin S has also been shown to have antibacterial effects against some bacteria, including Mycobacterium tuberculosis and Mycobacterium avium.</p>Fórmula:C37H45NO12Pureza:Min. 96 Area-%Forma y color:PowderPeso molecular:695.75 g/mol
![2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,6,9,11(2H)-tetrone, 5,17,19,21-tetrah…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0035KK.jpg&w=3840&q=75)
