CAS 13710-19-5

ácido tolfenámico

Descripción:

ácido tolfenámico es un fármaco antiinflamatorio no esteroideo (AINE) que pertenece a la clase de derivados del ácido antranílico. Se utiliza principalmente por sus propiedades analgésicas y antiinflamatorias, lo que lo hace efectivo en el tratamiento del dolor y la inflamación asociados con diversas condiciones. La estructura química de ácido tolfenámico presenta un grupo ácido carboxílico y un anillo aromático, que contribuyen a su actividad farmacológica. Exhibe una solubilidad moderada en agua y es más soluble en disolventes orgánicos, reflejando su naturaleza lipofílica. ácido tolfenámico actúa inhibiendo las enzimas ciclooxigenasas (COX), reduciendo así la síntesis de prostaglandinas, que son mediadores de la inflamación y el dolor. La sustancia se administra típicamente en forma oral y es conocida por su inicio de acción relativamente rápido. Además, se ha estudiado su posible uso en medicina veterinaria, particularmente en el tratamiento del dolor en animales. Al igual que otros AINE, puede tener efectos secundarios, incluidos trastornos gastrointestinales, y debe usarse con precaución en individuos con ciertas condiciones de salud.

Fórmula: C₁₄H₁₂ClNO₂

InChI: InChI=1/C14H12ClNO2/c1-9-11(15)6-4-8-12(9)16-13-7-3-2-5-10(13)14(17)18/h2-8,16H,1H3,(H,17,18)

Clave InChI: InChIKey=YEZNLOUZAIOMLT-UHFFFAOYSA-N

SMILES: N(C1=C(C(O)=O)C=CC=C1)C2=C(C)C(Cl)=CC=C2

Sinónimos:

• 1,2-Distearoyl-sn-glycero-3-phosphocholine, DSPC
• 2 (3-Chloro-2-Methylanilino)Benzoic Acid
• 2-((3-Chloro-2-Methylphenyl)Amino)-Benzoicaci
• 2-(3-Chloro-O-Toluidino)Benzoic Acid
• 2-[(3-Chloro-2-Methylphenyl)Amino]Benzoic Acid
• 2-[(4-Chloro-3-Methylphenyl)Amino]Benzoic Acid
• Anthranilic acid, N-(3-chloro-o-tolyl)-
• Benzoic acid, 2-[(3-chloro-2-methylphenyl)amino]-
• Clotam
• Gea 6414
• Gea6414
• Labotest-Bb Lt00772313
• Migea
• N-(2-Methyl-3-chlorophenyl)anthranilic acid
• N-(3-Chloro-o-tolyl)anthranilic acid
• N-(3-Chloro-ortho-tolyl) anthranilic acid
• Tolfedine
• Tolfenamate
• Tolfine
• n-(3-chloro-o-tolyl)-anthranilicacid
• Tolfenamic
• n-(3-chloro-o-tolyl)-anthranilicaci
• TOLFENAMIC ACID
• N-(3-CHLORO-2-METHYLPHENYL)ANTHRANILIC ACID
• 2 (3-Chloro-2-methylanilino)benzoic acid, 2-([3-Chloro-2-methylphenyl]amino)benzoic acid
• n-(2-methyl-3-chlorophenyl)anthranilicacid

Tolfenamic Acid

CAS: 13710-19-5

Fórmula: C₁₄H₁₂ClNO₂

Pureza: >97.0%(T)

Forma y color: White to Almost white powder to crystal

Peso molecular: 261.71

Ref: 3B-C2064

Tolfenamic acid, 99+%

CAS: 13710-19-5

Tolfenamic acid is a non-steroidal anti-inflammatory agent. It interferes with synthesis of -amyloid precursor protein, and thus A peptides, by promoting degradation of an essential transcription factor. It inhibits fMLP- and A23187-induced Ca2+ influx in human PMNL with an IC50 value of approximate

Fórmula: C₁₄H₁₂ClNO₂

Pureza: 99+%

Peso molecular: 261.71

Ref: 02-J61256

Tolfenamic Acid

CAS: 13710-19-5

Forma y color: Neat

Ref: 61-FOR3395.00

TOLFENAMIC ACID CRS

CAS: 13710-19-5

TOLFENAMIC ACID CRS

Fórmula: C₁₄H₁₂ClNO₂

Forma y color: Added Modified

Peso molecular: 261.7036

Ref: 41-Y0000154

2-[(3-chloro-2-methylphenyl)amino]benzoic acid

CAS: 13710-19-5

Fórmula: C₁₄H₁₂ClNO₂

Pureza: 97%

Forma y color: Solid

Peso molecular: 261.7036

Ref: IN-DA003SAR

Tolfenamic Acid

CAS: 13710-19-5

Tolfenamic Acid (GEA 6414) is one of the class of non-steroidal anti-inflammatory drugs (NSAIDs). It is used to treat the symptoms of migraine.

Fórmula: C₁₄H₁₂ClNO₂

Pureza: 99.71% - 99.97%

Forma y color: Solid

Peso molecular: 261.70

Ref: TM-T0784

Tolfenamic Acid

CAS: 13710-19-5

Fórmula: C₁₄H₁₂ClNO₂

Forma y color: White To Off-White Solid

Peso molecular: 261.71

Ref: 4Z-T-962

Tolfenamic Acid

CAS: 13710-19-5

Tolfenamic Acid

Pureza: ≥98%

Peso molecular: 261.7g/mol

Ref: 54-BUP17586

2-((3-Chloro-2-Methylphenyl)Amino)Benzoic Acid

CAS: 13710-19-5

2-((3-Chloro-2-Methylphenyl)Amino)Benzoic Acid

Pureza: 98%

Peso molecular: 261.70g/mol

Ref: 54-OR1009617

Tolfenamic-d4 Acid (Benzoic-3,4,5,6-d4)

CAS: 1246820-82-5, 13710-19-5

Pureza: 98 atom % D

Peso molecular: 265.73

Ref: 3U-D7725

Tolfenamic acid 1000 µg/mL in Acetonitrile

Producto controlado

CAS: 13710-19-5

Fórmula: C₁₄H₁₂ClNO₂

Forma y color: Single Solution

Peso molecular: 261.70

Ref: 04-A17591000AL-1000

Tolfenamic Acid

Producto controlado

CAS: 13710-19-5

Fórmula: C₁₄H₁₂ClNO₂

Forma y color: Neat

Peso molecular: 261.70

Ref: 86-MM3395.00

Tolfenamic acid

Producto controlado

CAS: 13710-19-5

Fórmula: C₁₄H₁₂ClNO₂

Forma y color: Neat

Peso molecular: 261.70

Ref: 04-C17591000

Tolfenamic Acid

Producto controlado

CAS: 13710-19-5

Applications Non-steroidal anti-inflammatory drugs (NSAIDs). A derivative of anthranilic acid, related structurally to Mefenamic and Flufenamic acids. Anti-inflammatory, analgesic.
References Pentikaeinen, P., et al.: Eur. J. Clin. Pharmacol., 19, 359 (1981), Bundscherer, A., et al.: Oncol. Rep., 19, 547 (2008), Elwood, P., et al.: Lancet, 373, 1301 (2009),

Fórmula: C₁₄H₁₂ClNO₂

Forma y color: Off-White

Peso molecular: 261.70

Ref: TR-T535300

Tolfenamic Acid

CAS: 13710-19-5

Fórmula: C₁₄H₁₂ClNO₂

Pureza: 97%

Forma y color: No data available.

Peso molecular: 261.71

Ref: 10-F519604

Tolfenamic Acid

CAS: 13710-19-5

Tolfenamic acid is a non-steroidal anti-inflammatory drug that has been shown to inhibit the MCL-1 protein, which is involved in the regulation of programmed cell death. It has been used for the treatment of bowel disease and can be given orally or rectally. Tolfenamic acid may be effective against inflammatory bowel diseases such as ulcerative colitis and Crohn's disease. Tolfenamic acid binds to anionic sites on the matrix of cartilage and inhibits the production of prostaglandin E2 by inhibiting cyclooxygenase activity. Tolfenamic acid has also been shown to reduce pain by inhibiting the enzyme COX-2, which is associated with inflammation. The drug also has a strong effect on human polymorphonuclear leukocytes (PMN).

Fórmula: C₁₄H₁₂ClNO₂

Pureza: Min. 97%

Forma y color: Powder

Peso molecular: 261.7 g/mol

Ref: 3D-FT28306