CAS 1375465-91-0

Fórmula: C14H14N4O2

InChI: InChI=1S/C14H14N4O2/c19-12(18-20)10-8-15-13(16-9-10)17-14(6-7-14)11-4-2-1-3-5-11/h1-5,8-9,20H,6-7H2,(H,18,19)(H,15,16,17)

Clave InChI: LIIWIMDSZVNYHY-UHFFFAOYSA-N

SMILES: C1CC1(C2=CC=CC=C2)NC3=NC=C(C=N3)C(=O)NO

N-Hydroxy-2-((1-Phenylcyclopropyl)Amino)Pyrimidine-5-Carboxamide

CAS: 1375465-91-0

N-Hydroxy-2-((1-Phenylcyclopropyl)Amino)Pyrimidine-5-Carboxamide

Fórmula: C₁₄H₁₄N₄O₂

Pureza: 98%

Peso molecular: 270.29

Ref: 54-OR1022994

5-Pyrimidinecarboxamide, N-hydroxy-2-[(1-phenylcyclopropyl)amino]-

CAS: 1375465-91-0

Fórmula: C₁₄H₁₄N₄O₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 270.2866

Ref: IN-DA0013IX

ACY-738

CAS: 1375465-91-0

ACY-738

Fórmula: C₁₄H₁₄N₄O₂

Pureza: ≥98%

Peso molecular: 270.29

Ref: 54-BUP07359

ACY-738

CAS: 1375465-91-0

N-Hydroxy-2-((1-phenylcyclopropyl)amino)pyrimidine-5-carboxamide

Fórmula: C₁₄H₁₄N₄O₂

Pureza: 98%

Peso molecular: 270.29

Ref: IN-DG627577

ACY-738

CAS: 1375465-91-0

ACY-738 demonstrates inhibitory activity against recombinant HDAC6 (IC50: 1.7 nM), with respective average selectivity over class I HDACs being 100-fold.

Fórmula: C₁₄H₁₄N₄O₂

Pureza: 98.62% - 99.89%

Forma y color: Yellow Solid

Peso molecular: 270.29

Ref: TM-T3509

5-Pyrimidinecarboxamide, N-hydroxy-2-[(1-phenylcyclopropyl)amino]-

CAS: 1375465-91-0

Pureza: 98%

Peso molecular: 270.2919922

Ref: 10-F865612

ACY-738

CAS: 1375465-91-0

ACY-738 is a small molecule that inhibits HDACs, which are enzymes that remove acetyl groups from proteins. These enzymes are often overexpressed in cancer cells and may be involved in the development of autoimmune diseases. ACY-738 has been shown to have synergistic effects with lymphocytic leukemia cells, which may be due to its ability to modulate the immune system. This drug also has immunomodulatory effects, including inhibition of T-cell proliferation and induction of apoptosis. ACY-738 can also reduce synaptic dysfunction and lysine residues by inhibiting the acetylation of histones and protein kinases. Acetylation is a process that affects gene expression by modifying chromatin structure. Acy-738 binds to serotonin reuptake transporters, preventing the reuptake of serotonin into presynaptic neurons, while also inhibiting serotonin synthesis.

Fórmula: C₁₄H₁₄N₄O₂

Pureza: Min. 95%

Forma y color: Off-White Solid

Peso molecular: 270.29 g/mol

Ref: 3D-BA168228