CAS 138605-00-2

β-Alanina, N,N-dimetil-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetiloxi)-3-eteni-dodecahidro-10,10b-dihidroxi-3,4a,7,7,10a-pentametil-1-oxo-1H-nafto[2,1-b]pirano-6-il éster, clorhidrato (1:1)

Descripción:

La sustancia química conocida como β-Alanina, N,N-dimetil-, con la estereoquímica especificada y el número CAS 138605-00-2, es un compuesto orgánico complejo caracterizado por su intrincada estructura, que incluye múltiples centros quirales y grupos funcionales como ésteres e hidroxilos. Este compuesto es un derivado de la β-alanina, un aminoácido que juega un papel en varios procesos biológicos. La presencia del grupo dimetilo sugiere una lipofilia mejorada, lo que puede influir en su solubilidad y actividad biológica. El grupo funcional éster indica una reactividad potencial, particularmente en reacciones de hidrólisis, que podrían afectar su estabilidad y biodisponibilidad. Además, la forma de clorhidrato implica que el compuesto es una sal, lo que probablemente mejora su solubilidad en entornos acuosos. En general, las características estructurales únicas de este compuesto pueden conferir propiedades farmacológicas específicas, lo que lo hace de interés en la química medicinal y la bioquímica. Sin embargo, serían necesarios estudios detallados para elucidar completamente su actividad biológica y aplicaciones potenciales.

Fórmula: C₂₇H₄₃NO₈·ClH

InChI: InChI=1S/C27H43NO8.ClH/c1-10-24(5)15-18(31)27(33)25(6)17(30)11-13-23(3,4)21(25)20(35-19(32)12-14-28(8)9)22(34-16(2)29)26(27,7)36-24;/h10,17,20-22,30,33H,1,11-15H2,2-9H3;1H/t17-,20-,21-,22-,24-,25-,26+,27-;/m0./s1

Clave InChI: InChIKey=VIRRLEDAYYYTOD-YHEOSNBFSA-N

SMILES: O[C@@]12[C@]3(C)[C@@]([C@H](OC(CCN(C)C)=O)[C@H](OC(C)=O)[C@@]1(C)O[C@](C=C)(C)CC2=O)(C(C)(C)CC[C@@H]3O)[H].Cl

Sinónimos:

• (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-5-yl acetate
• (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyl-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-6-yl 4-methylpentanoate hydrochloride (1:1)
• (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyl-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-6-yl N,N-dimethyl-beta-alaninate hydrochloride (1:1)
• (3R-(3-Alpha,4A-Beta,5-Beta,6-Beta,6A-Alpha,10-Alpha,10A-Beta,10B-Alpha))-Id
• 1H-Naphtho[2,1-b]pyran, β-alanine deriv.
• 6-(3-Dimethylaminopropionyl)forskolin hydrochloride
• Adehl
• Adehl (TN)
• Beta-Alanine,N,N-Dimethyl-,5-(Acetyloxy)-3-Ethenyldodecahydro-10,10B-Dihydrox
• Colforsin dapropate hydrochloride
• Colforsindapropatehydrochloride
• N,N-Dimethyl-(3R,4aR,5S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-
• Nkh 477
• Y-3,4A,7,7,10A-Pentamethyl-1-Oxo-1H-Naphtho(2,1-B)Pyran-6-Ylester,Hydrochlor
• β-Alanine, N,N-dimethyl-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl ester, hydrochloride
• β-Alanine, N,N-dimethyl-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl ester, hydrochloride (1:1)

NKH477

CAS: 138605-00-2

Fórmula: C₂₇H₄₄ClNO₈

Pureza: 98%

Peso molecular: 546.0932

Ref: IN-DA01E1RR

NKH477

CAS: 138605-00-2

NKH477

Pureza: ≥98%

Peso molecular: 546.09g/mol

Ref: 54-BUP21855

NKH477

CAS: 138605-00-2

NKH477 (Colforsin dapropate hydrochloride) is a derivative of forskolin with antidepressant activity.

Fórmula: C₂₇H₄₄ClNO₈

Pureza: 98% - 98%

Forma y color: Solid

Peso molecular: 546.09

Ref: TM-T16332

NKH 477

Producto controlado

CAS: 138605-00-2

Fórmula: C₂₇H₄₃NO₈·ClH

Forma y color: Neat

Peso molecular: 546.093

Ref: TR-N605000

NKH 477

CAS: 138605-00-2

NKH 477 is a drug that has been shown to increase the amount of calcium in the cytosol of cells. It has been found to be effective at low doses, which may be due to its ability to activate phospholipase C and stimulate the release of calcium from intracellular stores. NKH477 is an analogue of glucagon-like peptide 1 (GLP-1) and has been shown to have similar effects on cardiac muscle, but with less effect on pancreatic beta cells.
The effect of NKH 477 on cardiac muscle was studied in vitro using papillary muscle strips from guinea pig hearts. The drug was shown to cause relaxation of the muscles by stimulating ryanodine receptors, which are responsible for releasing calcium from intracellular stores. This drug may also have potential as a treatment for type 2 diabetes mellitus by activating GLP-1 receptors in the pancreas.

Fórmula: C₂₇H₄₄ClNO₈

Pureza: Min. 95%

Peso molecular: 546.09 g/mol

Ref: 3D-BN178886