CAS 139481-59-7: Candesartán

Descripción: Candesartán es un antagonista del receptor de angiotensina II que se utiliza principalmente en el tratamiento de la hipertensión y la insuficiencia cardíaca. Pertenece a la clase de medicamentos conocidos como sartanes, que actúan bloqueando la acción de la angiotensina II, una hormona que constriñe los vasos sanguíneos y aumenta la presión arterial. La fórmula química de Candesartán es C24H20N6O3, y presenta una estructura de bifenilo con un anillo de tetrazol, lo que contribuye a sus propiedades farmacológicas. Candesartán se administra típicamente en forma oral y es conocido por su larga vida media, lo que permite una dosificación una vez al día. Se absorbe bien en el tracto gastrointestinal, aunque su biodisponibilidad puede verse afectada por la ingesta de alimentos. Los efectos secundarios comunes pueden incluir mareos, fatiga e hipotensión, mientras que los efectos adversos graves pueden involucrar deterioro renal e hiperkalemia. Candesartán está contraindicado en el embarazo debido al posible daño al feto. En general, es un medicamento eficaz para el manejo de la hipertensión y la mejora de los resultados cardiovasculares en pacientes con insuficiencia cardíaca.

Fórmula: C₂₄H₂₀N₆O₃

InChI: InChI=1S/C24H20N6O3/c1-2-33-24-25-20-9-5-8-19(23(31)32)21(20)30(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-26-28-29-27-22/h3-13H,2,14H2,1H3,(H,31,32)(H,26,27,28,29)

Clave InChI: InChIKey=HTQMVQVXFRQIKW-UHFFFAOYSA-N

SMILES: O=C(O)C1=CC=CC=2N=C(OCC)N(C21)CC=3C=CC(=CC3)C=4C=CC=CC4C5=NN=NN5

Sinónimos:

• (1,1'-biphenyl)-4-yl)methyl)-
• (4S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
• 1-((2′-(1H-Tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid
• 1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 2-ethoxy-1-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylate
• 1H-Benzimidazole-7-carboxylic acid
• 1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
• 1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
• 2-Ethoxy-1-([4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl)-1H-1,3-benzodiazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl]-7-benzimidazolecarboxylic acid
• 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid
• 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazol-7-carboxylic acid
• 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid
• 2-Ethoxy-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid
• 2-Ethoxy-3-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl]methyl]-3H-benzoimidazole-4-carboxylic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• 2-ethoxy-1-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid
• 3-[[2'-(1H-Tetrazol-5-yl)biphenyl-4-yl]methyl]-2-ethoxy-3H-benzimidazole-4-carboxylic acid
• Blopress
• Blopress (TN)
• C07468
• Candesartan (USAN)
• Candesartan M1
• Candesartan [USAN:INN]
• Chebi:3347
• Cv 11974
• D00522
• imidazole-7-carboxylic acid
• lic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• Candesartan
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-

Candesartan, 98%

CAS: 139481-59-7

Candesartan is a selective AT1 (angiotensin II receptor 1) antagonist. Antagonism of angiotensin receptors inhibits …

• Fórmula: C₂₄H₂₀N₆O₃
• Pureza: 98%
• Forma y color: Powder, White to pale cream
• Peso molecular: 440.45

Candesartan Cilexetil Related Compound G (1-{[2'-(1H-Tetrazol-5-yl)biphenyl-4-yl]methyl}-2-ethoxybenzimidazole-7-carboxylic acid)

CAS: 139481-59-7

Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoi

• Fórmula: C₂₄H₂₀N₆O₃
• Forma y color: White Powder
• Peso molecular: 440.15969

Candesartan

CAS: 139481-59-7

Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of …

• Fórmula: C₂₄H₂₀N₆O₃
• Pureza: 98.30% - 99.55%
• Forma y color: Colorless Solid Crystalline
• Peso molecular: 440.47

Candesartan

CAS: 139481-59-7

• Fórmula: C₂₄H₂₀N₆O₃
• Pureza: 95%
• Forma y color: Solid
• Peso molecular: 440.454

Candesartan (Candesartan Cilexetil EP Impurity G, Candesartan Cilexetil USP Related Compound G)

CAS: 139481-59-7

• Fórmula: C₂₄H₂₀N₆O₃
• Forma y color: White To Off-White Solid
• Peso molecular: 440.46

Candesartan

CAS: 139481-59-7

• Fórmula: C₂₄H₂₀N₆O₃
• Peso molecular: 440.45

2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid (Candesartan)

CAS: 139481-59-7

• Fórmula: C₂₄H₂₀N₆O₃
• Forma y color: Neat
• Peso molecular: 440.45

Candesartan 100 µg/mL in Acetonitrile:Methanol

CAS: 139481-59-7

• Fórmula: C₂₄H₂₀N₆O₃
• Forma y color: Single Solution
• Peso molecular: 440.45

Candesartan

CAS: 139481-59-7

• Fórmula: C₂₄H₂₀N₆O₃
• Forma y color: Neat
• Peso molecular: 440.45

Candesartan

CAS: 139481-59-7

Impurity Candesartan Cilexetil EP Impurity G Applications Candesartan (Candesartan Cilexetil EP Impurity G) is an …

• Fórmula: C₂₄H₂₀N₆O₃
• Forma y color: Off White
• Peso molecular: 440.45

Candesartan - Bio-X ™

CAS: 139481-59-7

Candesartan is a drug that belongs to the class of angiotensin II receptor antagonists and …

• Fórmula: C₂₄H₂₀N₆O₃
• Pureza: Min. 95%
• Forma y color: Powder
• Peso molecular: 440.45 g/mol

Candesartan

CAS: 139481-59-7

Angiotensin II receptor I antagonist; anti-hypertensive

• Fórmula: C₂₄H₂₀N₆O₃
• Pureza: Min. 98 Area-%
• Forma y color: White Powder
• Peso molecular: 440.46 g/mol