CAS 139755-83-2

Sildenafil

Descripción:

Sildenafil es un compuesto farmacéutico conocido principalmente por su uso como tratamiento para la disfunción eréctil y la hipertensión arterial pulmonar. Funciona como un inhibidor selectivo de la fosfodiesterasa tipo 5 (PDE5), lo que lleva a un aumento de los niveles de monofosfato de guanosina cíclico (cGMP) y promueve la vasodilatación en el cuerpo cavernoso del pene, facilitando la erección en respuesta a la estimulación sexual. La fórmula molecular de Sildenafil es C22H30N6O4S, y tiene un peso molecular de aproximadamente 474.6 g/mol. La sustancia se administra típicamente por vía oral y está disponible en varias formulaciones, incluyendo tabletas y suspensiones orales. Sildenafil se caracteriza por su relativamente alta solubilidad en agua y solventes orgánicos, lo que ayuda en su biodisponibilidad. Los efectos secundarios comunes pueden incluir dolores de cabeza, enrojecimiento, dispepsia y alteraciones visuales. Es importante señalar que Sildenafil debe ser utilizado bajo supervisión médica, particularmente en individuos con condiciones cardiovasculares o aquellos que toman nitratos, debido a posibles interacciones y contraindicaciones.

Fórmula: C₂₂H₃₀N₆O₄S

InChI: InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)

Clave InChI: InChIKey=BNRNXUUZRGQAQC-UHFFFAOYSA-N

SMILES: O(CC)C1=C(C=C(S(=O)(=O)N2CCN(C)CC2)C=C1)C=3NC4=C(C(=O)N3)N(C)N=C4CCC

Sinónimos:

• 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
• 5-[2-Ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one
• 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-
• 5-[2-Ethoxy-5-(4-methylpiperazin-1-yl-sulphonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazol[4,3d]pyrimidin-7-one
• Sildenafil
• Sildenafil Cirtrate
• Piperazine, 1-[[3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methyl-
• Sildenafil Citrate
• 1H-Pyrazolo[4,3-d]pyrimidine, piperazine deriv.

Sildenafil Citrate

CAS: 139755-83-2, 171599-83-0

Fórmula: C₂₂H₃₀N₆O₄S·C₆H₈O₇

Pureza: >98.0%(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 666.70

Ref: 3B-S0986

Sildenafil

CAS: 139755-83-2

Forma y color: Neat

Ref: 61-FOR0254.09

Sildenafil 1.0 mg/ml in Methanol

CAS: 139755-83-2

Forma y color: Single Solution

Ref: 61-AMP0254.09-01

7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-

CAS: 139755-83-2

Fórmula: C₂₂H₃₀N₆O₄S

Pureza: 95%

Forma y color: Solid

Peso molecular: 474.5764

Ref: IN-DA001BO5

Sildenafil

CAS: 139755-83-2

Fórmula: C₂₂H₃₀N₆O₄S

Forma y color: White To Off-White Solid

Peso molecular: 474.58

Ref: 4Z-S-0652

Sildenafil

CAS: 139755-83-2

Forma y color: Neat

Ref: 86-MM0254.09

Sildenafil

CAS: 139755-83-2

Fórmula: C₂₂H₃₀N₆O₄S

Forma y color: Neat

Peso molecular: 474.58

Ref: 04-C16946490

Sildenafil

CAS: 139755-83-2

Pureza: 99.90%

Peso molecular: 474.58

Ref: 10-F979721

Sildenafil

CAS: 139755-83-2

Applications Sildenafil is an orally active selective type 5 cGMP phosphodiesterase inhibitor.
References Terrett, N.K., et al.: Bioorg. Med. Chem. Lett., 6, 1819 (1996); Goldstein, I., et al.: N. Engl. J. Med., 338, 1397 (1998);

Fórmula: C₂₂H₃₀N₆O₄S

Forma y color: Neat

Peso molecular: 474.58

Ref: TR-S435001

Sildenafil - Bio-X ™

CAS: 139755-83-2

Sildenafil is a potent inhibitor of cyclic guanosine monophosphate (cGMP) specific phosphodiesterase type 5 (PDE5), consequently preventing the degradation of cGMP in the smooth muscle cells of the pulmonary vasculature and penis. For this reason Sildenafil can be used to increase blood flow, decrease inflammation and mucus production in the lungs and also can be used in the treatment of erectile dysfunction in men. This is largely due to the increased availability of cGMP which can cause the relaxation of the smooth muscles to be prolonged.

Fórmula: C₂₂H₃₀N₆O₄S

Pureza: (%) Min. 95%

Forma y color: Powder

Peso molecular: 474.58 g/mol

Ref: 3D-BS164403

Sildenafil

CAS: 139755-83-2

Sildenafil is a pharmaceutical compound, which is a synthetic product derived from chemical processes. It functions as a selective inhibitor of the enzyme phosphodiesterase type 5 (PDE5). By inhibiting PDE5, sildenafil increases cyclic guanosine monophosphate (cGMP) levels within the smooth muscle cells of the corpus cavernosum. This leads to smooth muscle relaxation and vasodilation, allowing increased blood flow and facilitating penile erection in the presence of sexual stimulation.

Fórmula: C₂₂H₃₀N₆O₄S

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 474.58 g/mol

Ref: 3D-FS27828