CAS 141136-83-6

TRAMPA-6

Descripción:

TRAMPA-6, también conocido por su número CAS 141136-83-6, es un péptido sintético que actúa como un potente agonista del receptor de trombina, también conocido como el receptor activado por proteasas 1 (PAR-1). Este péptido se caracteriza por su capacidad para imitar la acción de la trombina, una enzima clave en la cascada de coagulación, influyendo así en varios procesos fisiológicos como la activación plaquetaria y la permeabilidad vascular. TRAMPA-6 se utiliza a menudo en investigaciones para estudiar la función plaquetaria y los mecanismos de trombosis y hemostasia. Su estructura típicamente incluye una secuencia de aminoácidos que le permite unirse y activar eficazmente el PAR-1, lo que lleva a vías de señalización posteriores que pueden afectar las respuestas celulares. El compuesto es de interés en estudios farmacológicos, particularmente en el contexto de enfermedades cardiovasculares y posibles intervenciones terapéuticas. Al igual que muchos péptidos, su estabilidad, solubilidad y biodisponibilidad son factores importantes que influyen en su aplicación tanto en estudios in vitro como in vivo.

Fórmula: C₃₄H₅₆N₁₀O₉

TRAP-6

CAS: 141136-83-6

SFLLRN corresponds to residues 42-47 of the thrombin receptor. The hexapeptide acts as a thrombin receptor activator. It caused half-maximal platelet aggregation at approx. 0.8 µM and was 5 times more potent than the parent peptide H-8105. In addition, SFLLRN is effective in causing tyrosine phosphorylation, inhibition of cAMP formation, and an increase in cytosolic Ca²⁺.

Fórmula: C₃₄H₅₆N₁₀O₉

Pureza: 98.4%

Forma y color: White Lyophilisate

Peso molecular: 748.88

Ref: 01-4017752

L-Seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-L-asparagine

CAS: 141136-83-6

Fórmula: C₃₄H₅₆N₁₀O₉

Pureza: 98%

Forma y color: Solid

Peso molecular: 748.8700

Ref: IN-DA003AP5

Thrombin Receptor Activator Peptide 6

CAS: 141136-83-6

Fórmula: C₃₄H₅₆N₁₀O₉

Pureza: ≥ 95.0%

Forma y color: White to beige powder

Peso molecular: 748.90

Ref: 7W-GK7137

Thrombin Receptor Activator Peptide 6

CAS: 141136-83-6

Thrombin Receptor Activator Peptide 6

Fórmula: C₃₄H₅₆N₁₀O₉

Pureza: By hplc: 98.4% (Typical Value in Batch COA)

Forma y color: white powder

Peso molecular: 748.87g/mol

Ref: 54-BIBA1005

TRAP-6

CAS: 141136-83-6

TRAP-6

Pureza: ≥98%

Peso molecular: 748.87g/mol

Ref: 54-BUP02503

TRAP-6

CAS: 141136-83-6

TRAP-6 (Thrombin Receptor Activator Peptide 6)(2TFA) is an agonist of protease-activated receptor 1 (PAR1).

Fórmula: C₃₄H₅₆N₁₀O₉

Pureza: >99.99%

Forma y color: Solid

Peso molecular: 748.87

Ref: TM-T7625

H-Ser-Phe-Leu-Leu-Arg-Asn-OH

CAS: 141136-83-6

H-Ser-Phe-Leu-Leu-Arg-Asn-OH is a biocompatible polymer that has been shown to have strong antioxidative properties. This polymer has been used in the development of a new class of drug for the treatment of inflammatory bowel disease, which may be due to its ability to inhibit toll-like receptor activity. H-Ser-Phe-Leu-Leu-Arg-Asn-OH also has potent immunosuppressive and antiinflammatory activities, and is stable at doses up to 200mg/kg. These properties make this polymer an attractive candidate for use as a therapeutic agent in treating bowel disease.

Fórmula: C₃₄H₅₆N₁₀O₉

Pureza: Min. 95%

Peso molecular: 748.87 g/mol

Ref: 3D-PAR-3943-PI

H-Ser-Phe-Leu-Leu-Arg-Asn-OH

CAS: 141136-83-6

Pureza: ≥96%

Peso molecular: 748.423

Ref: 10-F862560

TRAP-6 ammonium acetate salt

CAS: 141136-83-6

TRAP-6 is a biocompatible polymer that is used to prevent adhesion of platelets to the endothelium and activation of coagulation. TRAP-6 has been shown to be effective in preventing inflammatory bowel disease, as well as other bowel diseases, by inhibiting the release of inflammatory cytokines such as fibrinogen and erythropoietin. This drug has been shown to have clinical relevance in treating inflammatory bowel disease in animal models. TRAP-6 can also be used to inhibit the growth of bacteria by binding to bacterial cells or by inducing their death. In addition, TRAP-6 can bind with monoclonal antibodies and target specific cells for destruction.

Fórmula: C₃₄H₅₆N₁₀O₉

Pureza: Min. 95%

Peso molecular: 748.87 g/mol

Ref: 3D-FT110252