CAS 141368-69-6

H-GLY-ILE-LEU-GLY-PHE-VAL-PHE-THR-LEU-OH

Descripción:

La sustancia química identificada como H-GLY-ILE-LEU-GLY-PHE-VAL-PHE-THR-LEU-OH, con el número CAS 141368-69-6, es un péptido compuesto por una secuencia de aminoácidos. Este péptido presenta una combinación de cadenas laterales hidrofóbicas y polares, que contribuyen a sus propiedades estructurales y funcionales. La presencia de glicina (GLY), isoleucina (ILE), leucina (LEU), fenilalanina (PHE), valina (VAL) y treonina (THR) sugiere que puede exhibir características típicas de los péptidos, como actividad biológica potencial, incluyendo funciones similares a hormonas o neurotransmisores. El grupo hidroxilo terminal (-OH) indica que probablemente sea un péptido con un grupo carboxilo libre, lo que puede influir en su solubilidad y reactividad. Los péptidos como este a menudo se estudian por sus roles en sistemas biológicos, incluidos los caminos de señalización y los procesos metabólicos. Además, su estabilidad, interacción con receptores y aplicaciones terapéuticas potenciales son de gran interés en bioquímica y farmacología.

Fórmula: C₄₉H₇₅N₉O₁₁

Sinónimos:

• Matrix Protein M1 (58-66) (Influenza A Virus)
• H2N-Gilgfvftl-Oh
• Gly-Ile-Leu-Gly-Phe-Val-Phe-Thr-Leu
• Influenza Matrix Peptide
• Influenza Matrix Protein M1 (58-66)
• Influenza Virus Matrix Protein (58-66)
• Gilgfvftl

Matrix Protein M1 (58-66) (Influenza A virus)

CAS: 141368-69-6

Bachem ID: 4095875.

Fórmula: C₄₉H₇₅N₉O₁₁

Pureza: 96.8%

Forma y color: White Lyophilisate

Peso molecular: 966.19

Ref: 01-4095875

CEF1, Influenza Matrix Protein M1 (58-66)

CAS: 141368-69-6

CEF1, M1 (58-66) epitope from influenza A; GILGFVFTL is HLA-A2-restricted.

Fórmula: C₄₉H₇₅N₉O₁₁

Pureza: 98%

Forma y color: Solid

Peso molecular: 966.17

Ref: TM-TP1717

Flu mp 58

CAS: 141368-69-6

Portion of Influenza M

Fórmula: C₄₉H₇₅N₉O₁₁

Forma y color: Powder

Peso molecular: 966.18 g/mol

Ref: 3D-CRB1001165

Matrix Protein M1 (58-66) (Influenza A virus) acetate salt

CAS: 141368-69-6

Please enquire for more information about Matrix Protein M1 (58-66) (Influenza A virus) acetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Fórmula: C₄₉H₇₅N₉O₁₁

Pureza: Min. 95%

Peso molecular: 966.17 g/mol

Ref: 3D-FM109635

H-GILGFVFTL-OH

CAS: 141368-69-6

FluM1 (58-66) is a short part of the matrix protein of Influenza A virus which is the most abundant component of this enveloped virus localized under the viral lipid envelope. The GILGFVFTL epitope is highly conserved in Influenza A virus strains at a rate of 93% for 69 strains tested. Human Influenza epitopes may bind MHC molecules and then may be recognized by CD8+ cytotoxic T cells. Applications of FluM1 (58-66): FluM1 (58-66) is used to stimulate CTL responses in peripheral blood mononuclear cells (PBMCs). Then, ELISPOT assay is used to quantify peptide epitope specificity and IFN-γ releasing effector cells. FluM1 (58-66) has shown CTL responses qualified of immunodominant with restriction by HLA-A*02:01. It has also been detected CTL responses when FluM1 (58-66) is restricted by all HLA-C. Therefore, FluM1 (58-66) may help to understand the reaction of immune system against Influenza virus of each populations having different HLA type. FluM1 (58-66) has indeed prompted research to develop T-cell vaccine strategies capable of inducing specific CTL responses in patients upon immunization with Influenza M1 antigenic epitope. MVA-NP+M1 vaccine use GILGFVFTL epitope and is tested in clinical trial. Potential cross-reactivity with HIV-1 p17 Gag (77-85): Moreover, FluM1 (58-66) share similarities with HIV-1 p17 Gag (77-85) which can potentially show a cross-reactivity between these epitopes. It has been demonstrated a cross-reactivity and results suggest that immunity following infection by Influenza virus causes specific immune response to HIV-1 p17 Gag (77-85).

Fórmula: C₄₉H₇₅N₉O₁₁

Peso molecular: 966.18 g/mol

Ref: 3D-PP48052