CAS 1421958-41-9

GSK 2636771

CAS: 1421958-41-9

Selective inhibitor of phosphoinositide 3 kinase beta subunit (PI3Kβ) with IC50 = 5.2 nM. This compound competes with ATP for binding to the beta subunit of PI3K complex and inhibits the growth of phosphatase and tensin homolog (PTEN)-deficient tumor cells. Unlike the pan-PI3K inhibitors, GSK 2636771 does not cause side effects such as skin rash, hyperglycemia and diarrhea.

Fórmula: C₂₂H₂₂F₃N₃O₃

Pureza: Min. 95%

Peso molecular: 433.42 g/mol

Ref: 3D-BG166668