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CAS 1428315-82-5

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  • MRT-92
    Targetmol
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    MRT-92

    CAS:
    <p>MRT-92 is an antagonist of Smoothened (Smo) with anti-cancer activity, featuring a binding affinity (Ki) of 0.7 nM. It inhibits the Hedgehog signaling pathway by obstructing the overlapping binding sites within the transmembrane domain of the Smoothened receptor and suppresses the proliferation of cerebellar granule cells in rodents (IC50=0.4 nM). MRT-92 is utilized for research into cerebellar gliomas.</p>
    Fórmula:C33H34N4O5
    Forma y color:Solid
    Peso molecular:566.65

    Ref: TM-T200033