
CAS 1430219-69-4
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RI-OR2-TAT
CAS:<p>RI-OR2-TAT is a brain-penetrable inhibitor targeting β-amyloid (β-Amyloid) oligomerization. It is engineered by integrating the HIV protein transduction domain TAT into RI-OR2. RI-OR2-TAT binds to Aβ42 fibrils with a Kd value of 58-125 nM. It reduces Aβ aggregation and plaque levels, diminishes microglial activation and oxidative damage, and enhances the number of young neurons in the dentate gyrus.</p>Fórmula:C117H201N49O23Forma y color:SolidPeso molecular:2662.16
