CAS 1447-88-7

Hispidulina

Descripción:

Hispidulina es un compuesto flavonoide que se encuentra de forma natural, clasificado en la categoría de flavonas. Se deriva principalmente de diversas fuentes vegetales, particularmente de aquellas de la familia Asteraceae. La estructura química de Hispidulina presenta un esqueleto de cromona, que es característico de los flavonoides, e incluye grupos hidroxilo que contribuyen a su actividad biológica. Este compuesto es conocido por sus potenciales propiedades antioxidantes, antiinflamatorias y neuroprotectoras, lo que lo hace de interés en la investigación farmacológica. Además, se ha estudiado Hispidulina por sus efectos en diversas vías celulares, sugiriendo aplicaciones terapéuticas potenciales en condiciones como el cáncer y enfermedades neurodegenerativas. Su solubilidad y estabilidad pueden variar dependiendo del disolvente y las condiciones ambientales, lo cual es importante para su aplicación tanto en investigación como en uso medicinal potencial. En general, Hispidulina representa un área significativa de estudio dentro de la química de productos naturales, con investigaciones en curso destinadas a elucidar sus mecanismos de acción y potenciales beneficios para la salud.

Fórmula: C₁₆H₁₂O₆

InChI: InChI=1/C16H12O6/c1-21-16-11(19)7-13-14(15(16)20)10(18)6-12(22-13)8-2-4-9(17)5-3-8/h2-7,17,19-20H,1H3

Clave InChI: InChIKey=IHFBPDAQLQOCBX-UHFFFAOYSA-N

SMILES: OC1=C2C(OC(=CC2=O)C3=CC=C(O)C=C3)=CC(O)=C1OC

Sinónimos:

• 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-
• 4′,5,7-Trihydroxy-6-methoxyflavone
• 5,7,4′-Trihydroxy-6-methoxyflavone
• 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one
• 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one
• 6-Methoxy-5,7,4′-trihydroxyflavone
• 6-Methoxyapigenin
• 6-Methylscutellarein
• 6-O-Methylscutellarein
• Dinatin
• Flavone, 4′,5,7-trihydroxy-6-methoxy-
• Hispedulin
• Hispiludin
• NSC 122415
• Salvitin
• Scutellarein 6-Methyl Ether
• Hispidulin
• Hispidulin, >99%
• 1447-88-7
• Hispidulin(Dinatin)
• 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxychromen-4-one
• 4',5,7-Trihydroxy-6-methoxyflavone

Hispidulin

CAS: 1447-88-7

Hispidulin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₁₆H₁₂O₆

Pureza: (HPLC) ≥95%

Forma y color: Powder

Peso molecular: 300.27

Ref: 11-1451

4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-

CAS: 1447-88-7

Fórmula: C₁₆H₁₂O₆

Pureza: 99%

Forma y color: Solid

Peso molecular: 300.2629

Ref: IN-DA001K12

Hispidulin

CAS: 1447-88-7

Fórmula: C₁₆H₁₂O₆

Peso molecular: 300.27

Ref: 7W-GY8195

Hispidulin

CAS: 1447-88-7

Hispidulin

Pureza: ≥95%

Peso molecular: 300.26g/mol

Ref: 54-BUP17580

Hispidulin

CAS: 1447-88-7

Hispidulin has anti-oxidative, anti-inflammatory, anti-cancer, antiepileptic, neuroprotective, anti-osteoporotic and bone resorption attenuating effects, it targets the VEGF receptor 2-mediated PI3K/Akt/mTOR signaling pathway in endothelial cells, leading to the suppression of pancreatic tumor growth and angiogenesis. Hispidulin can ameliorate high glucose-mediated endothelial dysfunction via inhibiting PKCβII-associated NLRP3 inflammasome activation and NF-κB signaling, it has potential application in the prevention and treatment of diabetic vascular complications. Hispidulin can inhibit platelet aggregation by elevating cAMP levels by a mechanism different from that of theophylline or PGE1.

Fórmula: C₁₆H₁₂O₆

Pureza: 95%~99%

Peso molecular: 300.266

Ref: BP-BP0730

Hispidulin

CAS: 1447-88-7

Hispidulin, a natural flavone with a broad spectrum of biological activities, is a Pim-1 inhibitor (IC50: 2.71 μM).

Fórmula: C₁₆H₁₂O₆

Pureza: 98.53% - 99.87%

Forma y color: Solid

Peso molecular: 300.26

Ref: TM-TQ0201

Hispidulin

CAS: 1447-88-7

Fórmula: C₁₆H₁₂O₆

Peso molecular: 300.27

Ref: 4Z-H-031001

Hispidulin

CAS: 1447-88-7

Oxygen-heterocyclic compound

Fórmula: C₁₆H₁₂O₆

Pureza: ≥ 95.0 % (HPLC)

Forma y color: Powder

Peso molecular: 300.27

Ref: 5G-83335

Hispidulin

CAS: 1447-88-7

Hispidulin is a naturally occurring flavonoid compound, which is predominantly derived from plants such as Salvia and Artemisia species. This bioactive compound exhibits a broad spectrum of pharmacological activities that have garnered attention in the scientific community. Its mode of action involves the modulation of cellular pathways, including the inhibition of enzymes like cyclooxygenases, which are pivotal in inflammatory responses. Furthermore, Hispidulin has been shown to influence neurotransmitter systems, including GABAergic activity, indicating potential neuroprotective effects.

Fórmula: C₁₆H₁₂O₆

Pureza: Min. 98 Area-%

Forma y color: Off-White Powder

Peso molecular: 300.26 g/mol

Ref: 3D-FH73251

Hispidulin - Bio-X ™

CAS: 1447-88-7

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Fórmula: C₁₆H₁₂O₆

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 300.26 g/mol

Ref: 3D-BH300089

Hispidulin

CAS: 1447-88-7

Pureza: 99%

Peso molecular: 300.2659912

Ref: 10-F814360

Hispidulin

Producto controlado

CAS: 1447-88-7

Applications Hispidulin is a potent benzodiazepine (BZD) receptor ligand.

Fórmula: C₁₆H₁₂O₆

Forma y color: Neat

Peso molecular: 300.27

Ref: TR-H456340

Hispidulin

CAS: 1447-88-7

Hispidulin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₁₆H₁₂O₆

Pureza: (HPLC) ≥98%

Forma y color: Powder

Peso molecular: 300.27

Ref: 11-1451S