CAS 145435-72-9

Gamithromicina

Descripción:

Gamithromicina es un antibiótico macrólido utilizado principalmente en medicina veterinaria, particularmente para el tratamiento de infecciones respiratorias en ganado. Se caracteriza por su actividad antibacteriana de amplio espectro, que ataca una variedad de bacterias Gram-positivas y algunas Gram-negativas. Gamithromicina actúa inhibiendo la síntesis de proteínas bacterianas al unirse a la subunidad ribosomal 50S, interrumpiendo efectivamente el crecimiento y la reproducción de las bacterias. El compuesto es conocido por su larga vida media, lo que permite una dosificación menos frecuente en comparación con otros antibióticos. Se administra típicamente por inyección y es preferido por su eficacia contra patógenos como las especies de Mycoplasma y Pasteurella. Además, Gamithromicina tiene un perfil de seguridad favorable cuando se usa según las indicaciones en animales, aunque su uso en animales productores de alimentos está regulado para prevenir residuos de antibióticos en productos cárnicos. Al igual que con todos los antibióticos, el uso responsable es crucial para mitigar el riesgo de desarrollar bacterias resistentes a los antibióticos.

Fórmula: C₄₀H₇₆N₂O₁₂

InChI: InChI=1S/C40H76N2O12/c1-15-17-42-21-22(3)33(44)40(11,48)29(16-2)52-36(46)26(7)32(53-30-20-39(10,49-14)34(45)27(8)51-30)25(6)35(38(9,47)19-23(42)4)54-37-31(43)28(41(12)13)18-24(5)50-37/h22-35,37,43-45,47-48H,15-21H2,1-14H3/t22-,23+,24+,25-,26+,27-,28-,29+,30-,31+,32-,33+,34-,35+,37-,38+,39+,40+/m0/s1

Clave InChI: InChIKey=VWAMTBXLZPEDQO-UZSBJOJWSA-N

SMILES: O([C@@H]1[C@@H](C)[C@H](O[C@H]2C[C@](OC)(C)[C@@H](O)[C@H](C)O2)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)CN(CCC)[C@H](C)C[C@@]1(C)O)[C@H]3[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3

Sinónimos:

• (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-1-oxa-7-azacyclopentadecan-15-one
• (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-Cmethyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy]-1-oxa-7-azacyclopentadecan-15-one
• 1-Oxa-7-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-
• 1-Oxa-7-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-, [2R-(2R*,3S*,4R*,5S*,8R*,10R*,11R*,12S*,13S*,14R*)]-
• Gamithormycin
• Gamithromycin
• Ml 1709460
• Zactran
• (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-7-azacyclopentadecan-15-one
• 1-Oxa-7-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-
• 1-Oxa-7-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, [2R-(2R*,3S*,4R*,5S*,8R*,10R*,11R*,12S*,13S*,14R*)]-

1-Oxa-7-azacyclopentadecan-15-one,13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-7-propyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy]-,[2R-(2R*,3S*,4R*,5S*,8R*,10R*,11R*,12S*,13S*,14R*)]-

CAS: 145435-72-9

Fórmula: C₄₀H₇₆N₂O₁₂

Pureza: 95%

Forma y color: Solid

Peso molecular: 777.0376

Ref: IN-DA00HXF7

Gamithromycin

CAS: 145435-72-9

Fórmula: C₄₀H₇₆N₂O₁₂

Pureza: 95.0 - 103.0 % (dried basis)

Forma y color: Light-yellow to off-white powder or solid

Peso molecular: 777.04

Ref: 7W-GC5312

(2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-Hydroxy-6-Methyltetrahydro-2H-Pyran-2-Yl)Oxy)-2-Ethyl-3,4,10-Trihydroxy-13-(((2R,4R,5S,6S)-5-Hydroxy-4-Methoxy-4,6-Dimethylt

CAS: 145435-72-9

(2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-Hydroxy-6-Methyltetrahydro-2H-Pyran-2-Yl)Oxy)-2-Ethyl-3,4,10-Trihydroxy-13-(((2R,4R,5S,6S)-5-Hydroxy-4-Methoxy-4,6-Dimethylt

Pureza: 95%

Peso molecular: 777.04g/mol

Ref: 54-OR1025800

Gamithromycin

CAS: 145435-72-9

Gamithromycin

Pureza: ≥98%

Peso molecular: 777.04g/mol

Ref: 54-BUP14548

Gamithromycin 100 µg/mL in Methanol

Producto controlado

CAS: 145435-72-9

Fórmula: C₄₀H₇₆N₂O₁₂

Forma y color: Single Solution

Peso molecular: 777.04

Ref: 04-A13998500ME-100

Gamithromycin

Producto controlado

CAS: 145435-72-9

Fórmula: C₄₀H₇₆N₂O₁₂

Forma y color: Neat

Peso molecular: 777.04

Ref: 04-C13998500

Gamithromycin

CAS: 145435-72-9

Fórmula: C₄₀H₇₆N₂O₁₂

Peso molecular: 777.05

Ref: 4Z-G-057003

Gamithromycin

CAS: 145435-72-9

Gamithromycin (ML-1709460) is a macrolide compound with antibacterial activity.

Fórmula: C₄₀H₇₆N₂O₁₂

Pureza: 99.38%

Forma y color: Solid

Peso molecular: 777.04

Ref: TM-T3629

Gamithromycin

Producto controlado

CAS: 145435-72-9

Stability Hygroscopic
Applications A macrolide compound which is known to have antibacterial activity, and is useful in the therapy of bacterial infections in mammals. Antibiotic.
References Broto, P., et al.: Eur. J. Med. Chem., 19, 71 (1984), Farrar, V., et al.: J. Med. Chem., 36, 3517 (1993), Clark, D., et al.: J. Pharm. Sci., 88, 807 (1999),

Fórmula: C₄₀H₇₆N₂O₁₂

Forma y color: Neat

Peso molecular: 777.04

Ref: TR-G195000

Gamithromycin

CAS: 145435-72-9

Gamithromycin is a macrolide antibiotic with action on bacterial protein synthesis and is used for treating respiratory infections in cattle, pigs, and sheep.

Fórmula: C₄₀H₇₆N₂O₁₂

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 777.04 g/mol

Ref: 3D-AG16733