CAS 146-22-5
:2H-1,4-Benzodiazepin-2-ona, 1,3-dihidro-7-nitro-5-fenil-
Descripción:
2H-1,4-Benzodiazepin-2-ona, 1,3-dihidro-7-nitro-5-fenil- (CAS 146-22-5) es un compuesto químico que pertenece a la clase de las benzodiazepinas, caracterizado por una estructura de anillo fusionado de benceno y diazepina. Este compuesto exhibe típicamente una variedad de propiedades farmacológicas, incluyendo efectos ansiolíticos, sedantes y relajantes musculares, aunque su actividad específica puede variar según las modificaciones estructurales. La presencia de un grupo nitro en la posición 7 y un grupo fenilo en la posición 5 contribuye a su reactividad química única y potencial actividad biológica. En términos de propiedades físicas, las benzodiazepinas suelen mostrar solubilidad moderada en disolventes orgánicos y solubilidad limitada en agua, lo que puede influir en su biodisponibilidad y farmacocinética. La estructura molecular del compuesto permite interacciones con el sistema nervioso central, principalmente a través de la modulación de los receptores GABA, lo que lo hace de interés en la química medicinal y la farmacología. Las precauciones de seguridad y manejo son esenciales debido a la posible toxicidad y efectos secundarios asociados con los derivados de benzodiazepinas.
Fórmula:C15H11N3O3
InChI:InChI=1/C18H17ClN2O/c1-11(2)16-18(22)20-15-9-8-13(19)10-14(15)17(21-16)12-6-4-3-5-7-12/h3-11,16H,1-2H3,(H,20,22)
Clave InChI:InChIKey=KJONHKAYOJNZEC-UHFFFAOYSA-N
SMILES:N(=O)(=O)C=1C=C2C(=NCC(=O)NC2=CC1)C3=CC=CC=C3
Sinónimos:- 1,3-Dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepin-2-one
- 1,3-Dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepine-2-one
- 2,3-Dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-one
- 7-Nitro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
- 7-Nitro-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one
- 7-Nitro-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
- Benzalin
- Calsmin
- Dormicum
- Dormicum (anticonvulsant)
- Dormin 5
- Eatan
- Epibenzalin
- Epinelbon
- Eunoctin
- Hipnax
- Hipsal
- Imeson
- Insomin
- Ipersed
- La 1
- Megadon
- Mogadan
- Mogadon
- Mogadone
- N-Desmethylnimetazepam
- Nelbon
- Neozepam
- Neuchlonic
- Nipam
- Nitrados
- Nitravet
- Nitrazepam
- Nitrenpax
- Nitrosun
- Noctesed
- Nsc 58775
- Paxisyn
- Pelson
- Radedorm
- Relact
- Remnos
- Ro 4-5360
- Ro 5-3059
- Somitran
- Somnased
- Somnibel
- Somnite
- Sonebon
- Sonnolin
- Surem
- Unisomnia
- Xiaoxipan
- nitrazepam--dea schedule iv item
- 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-nitro-5-phenyl-
- 1,3-dihydro-7-nitro-5-phenyl-1,4-benzodiazepin-2-one
- 7-chloro-5-phenyl-3-(propan-2-yl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
- Apodorm
- 1H-1,4-Benzodiazepin-2(3H)-one, 7-chloro-3-isopropyl-5-phenyl-
- Cerson
- Eunoktin
- 7-Nitro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one
- 1,3-dihydro-7-nitro-5-phenyl-2h-4-benzodiazepin-2-one
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Encontrado 13 productos.
Nitrazepam
CAS:Producto controladoNitrazepam is a benzodiazepine with hypnotic and sedative properties. It binds to the GABA-A receptor in the brain, leading to an increase in the frequency of chloride ion channel opening. Nitrazepam has synergistic effects with other drugs such as antidepressants, antipsychotics, and antihistamines. It is used for the treatment of insomnia and anxiety disorders. Nitrazepam has been shown to have a rate constant of 0.068 L/mg at 25°C in human serum. This drug can be analyzed by gas chromatography following derivatization with methanol or ethyl acetate. Nitrazepam is one of many compounds found in wastewater that may cause long-term damage to the environment during wastewater treatment. The presence of nitrazepam in biological samples can be determined by a control analysis using a method that employs high performance liquid chromatography (HPLC). Nitrazepam can also be detected by polymerase chain reactionFórmula:C15H11N3O3Pureza:Min. 95%Forma y color:SolidPeso molecular:281.27 g/molNitrazepam
CAS:Producto controladoNitrazepam is a peptide that is used as a research tool for the study of ion channels and protein interactions. It has an affinity for GABA receptors and can be used to study the effects of receptor activation. Nitrazepam also binds to antibody-producing cells, which leads to increased production of antibodies by these cells. This drug is an inhibitor that blocks the binding of ligands to their receptors, thereby preventing or reversing the effects of ligand binding on cell function. Nitrazepam is a high-purity reagent with CAS No. 146-22-5, which can be used in life science research and cell biology.
Fórmula:C15H11N3O3Peso molecular:281.27 g/molNITRAZEPAM CRS - * PSY
CAS:Producto controladoNITRAZEPAM CRS - * PSYFórmula:C15H11N3O3Forma y color:Added ModifiedPeso molecular:281.2661Nitrazepam
CAS:Producto controladoNitrazepamFórmula:C15H11N3O3Pureza:100.0%Forma y color:White To Off-WhitePeso molecular:281.08004Nitrazepam (1.0 mg/mL in Acetonitrile)
CAS:Producto controladoFórmula:C15H11N3O3Forma y color:ColourlessPeso molecular:281.27Nitrazepam
CAS:Producto controladoApplications Anticonvulsant; hypnotic.Controlled substance (depressant).
References Rieder, et al.: Arzneim.-Forsch., 23, 212 (1973), Kangas, L., Acta Pharmacol. Toxicol., 45, 16 (1979), Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 9, 487 (1980).Fórmula:C15H11N3O3Forma y color:White To Off-WhitePeso molecular:281.27Nitrazepam (100μg/ml in Acetonitrile)
CAS:Producto controladoFórmula:C15H11N3O3Forma y color:ColourlessPeso molecular:281.27
