CAS 1463-10-1

5-Metiluridina

Descripción:

5-Metiluridina, también conocido como ribotimidina, es un nucleósido que consiste en la base de pirimidina uracilo con un grupo metilo unido a la posición 5 del anillo de uracilo. Esta modificación mejora la estabilidad y funcionalidad de las moléculas de ARN, particularmente en el contexto del tRNA, donde juega un papel en el correcto plegamiento y función de la molécula. La fórmula química de 5-Metiluridina es C10H13N2O5, y se caracteriza por su capacidad para participar en enlaces de hidrógeno debido a la presencia de grupos hidroxilo y amino. Este compuesto es soluble en agua y presenta un punto de fusión relativamente bajo. 5-Metiluridina es de interés en la investigación bioquímica y tiene aplicaciones potenciales en los campos de la biología molecular y la farmacología, particularmente en el estudio de las modificaciones del ARN y sus efectos en la expresión génica y la síntesis de proteínas. Su número CAS, 1463-10-1, se utiliza para la identificación en bases de datos químicas y contextos regulatorios.

Fórmula: C₁₀H₁₄N₂O₆

InChI: InChI=1/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6+,7?,9-/m1/s1

Clave InChI: InChIKey=DWRXFEITVBNRMK-JXOAFFINSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(C)=C2

Sinónimos:

• 1-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,3-dihydropyrimidine-2,4-dione
• 1-[3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
• 1-[3,4-Dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
• 1-β-<span class="text-smallcaps">D</span>-Ribofuranosylthymine
• 2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• 5-Me-U
• 5-Methyl-Uridine
• 5-methyl-1-(beta-L-ribofuranosyl)pyrimidine-2,4(1H,3H)-dione
• 5-methyl-1-[(2xi)-beta-D-threo-pentofuranosyl]pyrimidine-2,4(1H,3H)-dione
• 5-methyl-1-pentofuranosylpyrimidine-2,4(1H,3H)-dione
• Ribosylthymine
• Ribothymidine
• Thymine riboside
• Uridine, 5-methyl-
• β-<span class="text-smallcaps">D</span>-Ribofuranoside, thymine-1
• 5-Methyluridine
• 2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-β-D-ribofuranosyl-
• 5-methyuridine
• BETA-RIBOFURANOSIDE
• ribosylthymine/5-methyluridine
• 1-(BETA-D-RIBOFURANOSYL)THYMINE
• 1-β-D-Ribofuranosylthymine
• 5-methyluridine/ribothymidine
• 5-METHYL-D-URIDINE
• 5-Methyluridine (Patent )
• 5-METHYL-1-BETA-D-RIBOFURANOSYL URACIL
• 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
• Methyluridine
• 5-methyl-uridin
• THYMINERIBOSIDE
• BETA-D-THYMINE RIBOSIDE
• 1-(BETA-D-RIBOFURANOSYL)THYMIDINE

5-Methyluridine

CAS: 1463-10-1

Fórmula: C₁₀H₁₄N₂O₆

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 258.23

Ref: 3B-M1405

5-Methyluridine, 99%

CAS: 1463-10-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₁₀H₁₄N₂O₆

Pureza: 99%

Peso molecular: 258.23

Ref: 02-H64259

Uridine, 5-methyl-

CAS: 1463-10-1

Fórmula: C₁₀H₁₄N₂O₆

Pureza: 95%

Forma y color: Solid

Peso molecular: 258.2280

Ref: IN-DA001DVT

5-Methyluridine

CAS: 1463-10-1

5-Methyluridine

Pureza: ≥98%

Peso molecular: 258.23g/mol

Ref: 54-BUP18363

5-Methyluridine

CAS: 1463-10-1

Fórmula: C₁₀H₁₄N₂O₆

Peso molecular: 258.23

Ref: 7W-GE5148

5-Methyluridine

CAS: 1463-10-1

5-Methyluridine

Fórmula: C₁₀H₁₄N₂O₆

Pureza: 97%

Forma y color: white solid

Peso molecular: 258.23g/mol

Ref: 54-OR52639

5-Methyluridine

CAS: 1463-10-1

5-Methyluridine, a methylated nucleoside in human fluids, is higher in tumor patients; targeted by hypomethylating drugs in cancer therapy.

Fórmula: C₁₀H₁₄N₂O₆

Pureza: 99.72%

Forma y color: Solid

Peso molecular: 258.23

Ref: TM-T5282

5-Methyluridine

CAS: 1463-10-1

Applications A primary degradation product of tRNA, an urinary nucleoside as biological marker for patients with colorectal cancer.
References Borek, E., et al.: Cancer Res., 37, 3362 (1977), Sander, G., et al.: Clin. Sci.,71, 367 (1986), Sander, G., et al.: Ann. Nutr. Metab., 30, 137 (1986), Rasmuson, T., et al.: Acta Oncol., 34, 61 (1995),

Fórmula: C₁₀H₁₄N₂O₆

Forma y color: Neat

Peso molecular: 258.23

Ref: TR-M338190

5-Methyluridine

CAS: 1463-10-1

5-Methyluridine is a nucleoside that is used to inhibit the replication of cells. It is also used for the treatment of cancer, infectious diseases, and other conditions. 5-Methyluridine inhibits cellular replication by binding to ribothymidine and uridine in the nucleus. The inhibition of cellular proliferation is due to a lack of dna synthesis and RNA synthesis. This nucleoside has been shown to have inhibitory properties against mouse tumor cells grown in vitro, as well as the wild-type strain grown in vivo. 5-Methyluridine may be useful for the treatment of cancer tissues because it can suppress the growth of tumors by inhibiting their ability to replicate.

Fórmula: C₁₀H₁₄N₂O₆

Pureza: Min. 98 Area-%

Forma y color: White Powder

Peso molecular: 258.23 g/mol

Ref: 3D-NM04922

5-Methyluridine

CAS: 1463-10-1

Fórmula: C₁₀H₁₄N₂O₆

Pureza: 95%

Forma y color: Solid, White to almost white crystal powder

Peso molecular: 258.23

Ref: 10-F212233

5-Methyluridine extrapure, 98%

CAS: 1463-10-1

Fórmula: C₁₀H₁₄N₂O₆

Pureza: min. 98%

Forma y color: White to off - white, Crystalline powder, Clear, Colourless

Peso molecular: 258.23

Ref: SR-77337

5-Methyluridine

CAS: 1463-10-1

Fórmula: C₁₀H₁₄N₂O₆

Peso molecular: 258.23

Ref: ST-EA-CP-Z6011