CAS 146508-65-8

4(1H)-Quinazolinona, 6-cloro-2-[5-cloro-2-(fosfonooxi)fenil]-, sal disódica

Descripción:

4(1H)-Quinazolinona, 6-cloro-2-[5-cloro-2-(fosfonooxi)fenilo]-, sal disódico, identificado por el número CAS 146508-65-8, es un compuesto químico caracterizado por su estructura central de quinazolinona, que es un compuesto bicíclico que contiene un anillo de benceno y un anillo de pirimidina fusionados. La presencia de sustituyentes de cloro y un grupo fosfonooxi contribuye a su reactividad única y potencial actividad biológica. Como sal disódica, es probable que exhiba una mayor solubilidad en entornos acuosos, lo que lo hace adecuado para diversas aplicaciones en química medicinal y bioquímica. Este compuesto puede poseer propiedades que son de interés en el desarrollo de fármacos, particularmente en la orientación a vías biológicas específicas. Sus características estructurales sugieren interacciones potenciales con enzimas o receptores, que podrían explorarse con fines terapéuticos. Sin embargo, serían necesarios estudios detallados para elucidar completamente su perfil farmacológico y aplicaciones potenciales.

Fórmula: C₁₄H₉Cl₂N₂O₅P・2Na

FLsharp™ - Phosphate, disodium salt

CAS: 146508-65-8

FLsharp™ - Phosphate, disodium salt is a fluorogenic water soluble substrate for phosphatase enzymes. After cleavage of the substrate by phosphatase activity an insoluble product is formed that is highly fluorescent in the solid state. Upon UV irradiation this very stable fluorophore emits green light in the 530 nm range for an extended period of time. FLsharp™ - Phosphate is a unique substrate - optimized for the detection of phosphatase activity in solid matrices such as agar media, tissuesections or microscopic preparations. FLsharp™ - Phosphate, disodium salt is used in microbiology as asubstrate for bacterial phosphatases. The substrate is suitable to detect the specific phosphatase activity of S. aureus or C. perfringensin food samples or clinical samples. Colonies growing on plating media supplemented with FLsharp™ emit green light upon UV light excitation(Excitation max: 365 nm; emission max: 530 nm). The enzyme product formed from FLsharp™ in agar plating media enables high precision for the localization of the relevant colonies on the plate. As a result small bacteria colonies of phosphatase-positive bacteria can be detected already after a short incubation time.  In cytochemical and histochemical imaging FLsharp™ - Phosphate, disodiumsalt can be used as a substrate for Alkaline Phosphatase (AP)-coupled antibodies. The fluorophore that is released from FLsharp™ - Phosphateby phosphatase activity will precipitate. This insoluble fluorophoreen ables a precise localization of the antibody-bound epitope in cells or tissues under a fluorescence microscope or fluorescence imaging system. The green fluorescence of FLsharp™ can be clearly differentiated from autofluorescence or counterstainings such as (blue) DAPI or (red) Alexafluorophores.

Fórmula: C₁₄H₇Cl₂N₂Na₂O₅P

Pureza: Min. 95.0 Area-%

Peso molecular: 431.08 g/mol

Ref: 3D-C-3453