CAS 147-94-4

Citarabina

Descripción:

Citarabina, también conocido como arabinosido de citosina, es un análogo de nucleósido utilizado principalmente como agente antineoplásico en el tratamiento de ciertos tipos de leucemia y linfoma. Su fórmula química es C9H13N3O5, y presenta un moiety de azúcar (arabinosido) unido a una base de citosina. Citarabina se caracteriza por su capacidad para inhibir la síntesis de ADN, lo que lo hace efectivo en el objetivo de células cancerosas que se dividen rápidamente. Se administra típicamente por inyección, ya que se absorbe mal cuando se toma por vía oral. El compuesto es conocido por su vida media relativamente corta, lo que requiere infusión continua o dosificación frecuente en entornos clínicos. Los efectos secundarios comunes incluyen mielosupresión, que puede llevar a una mayor susceptibilidad a infecciones y hemorragias, así como trastornos gastrointestinales. Debido a su mecanismo de acción, Citarabina a menudo se utiliza en combinación con otros agentes quimioterapéuticos para mejorar la eficacia terapéutica. Su uso se monitorea cuidadosamente, dado el potencial de toxicidad significativa, particularmente en pacientes con condiciones preexistentes o aquellos que reciben terapias concurrentes.

Fórmula: C₉H₁₃N₃O₅

InChI: InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1

Clave InChI: InChIKey=UHDGCWIWMRVCDJ-CCXZUQQUSA-N

SMILES: O[C@@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(N)C=C2

Sinónimos:

• (Arabinofuranosyl)cytosine
• 1-(Arabinofuranosyl)cytosine
• 1-(β-<span class="text-smallcaps">D</span>-Arabinofuranosyl)cytosine
• 1-(β-D-Arabinofuranosyl)cytosine
• 1-b-D-Arabinofuranosylcytosine
• 1-β-<span class="text-smallcaps">D</span>-Arabinosylcytosine
• 1-β-Arabinofuranosylcytosine
• 1-β-D-Arabinosylcytosine
• 2(1H)-Pyrimidinone, 4-amino-1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-
• 2(1H)-Pyrimidinone, 4-amino-1-β-D-arabinofuranosyl-
• 4-Amino-1-Beta-D-Arabinofuranosyl-2(1H)-Pyrimidinone
• 4-Amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
• 4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidine
• 4-Amino-1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-2(1H)-pyrimidinone
• 4-Amino-1-β-D-Arabinofuranosyl-2(1H)-pyrimidinone
• 4-amino-1-(D-arabinofuranosyl)pyrimidin-2(1H)-one
• 4-amino-1-(beta-D-arabinofuranosyl)pyrimidin-2(1H)-one
• 4-amino-1-[(2R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one
• 4-amino-1-pentofuranosylpyrimidin-2(1H)-one
• Ac 1075
• Alexan
• Ara-C
• Ara-cell
• ArabinoFuranosylcytosine
• Arabinocytidine
• Arabinocytosine
• Arabinoside C
• Arabitin
• Aracytidine
• Aracytin
• Aracytine
• Arafcyt
• Chx 3311
• Citarabina
• Citozar
• Cyclocide
• Cylocide
• Cylocide N
• Cytarabin
• Cytarabine
• Cytarabinoside
• Cytosar
• Cytosar U
• Cytosine Arabinoside
• Cytosine β-<span class="text-smallcaps">D</span>-arabinofuranoside
• Cytosine β-<span class="text-smallcaps">D</span>-arabinoside
• Cytosine β-D-arabinofuranoside
• Cytosine β-D-arabinoside
• Cytosine, 1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-
• Cytosine, 1-β-D-arabinofuranosyl-
• Cytosine-1-β-<span class="text-smallcaps">D</span>-arabinofuranoside
• Cytosine-1-β-D-arabinofuranoside
• Cytosine-1-β-arabinofuranoside
• DepoCyt
• DepoCyte
• Erpalfa
• Iretin
• Mk 8242
• N-(2-oxo-2,3-dihydropyrimidin-4-yl)-D-arabinofuranosylamine
• Nsc 287459
• Nsc 63878
• Sch 900242
• Spongocytidine
• Tarabine PFS
• U 19920
• U 19920A
• Udicil
• ara-Cytosine

CYTARABINE RS

CAS: 147-94-4

CYTARABINE RS

Fórmula: C₉H₁₃N₃O₅

Peso molecular: 243.2166

Ref: 41-ICRS46472

CYTARABINE CRS

CAS: 147-94-4

CYTARABINE CRS

Fórmula: C₉H₁₃N₃O₅

Forma y color: Added Modified

Peso molecular: 243.2166

Ref: 41-C3350000

Cytarabine

CAS: 147-94-4

Cytarabine

Fórmula: C₉H₁₃N₃O₅

Pureza: 99.9%

Forma y color: White

Peso molecular: 243.08552

Ref: 47-383

Cytarabine

CAS: 147-94-4

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Fórmula: C₉H₁₃N₃O₅

Forma y color: White Off-White Powder

Peso molecular: 243.08552

Ref: 45-1162002

4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one

CAS: 147-94-4

Fórmula: C₉H₁₃N₃O₅

Pureza: 95%

Forma y color: Solid

Peso molecular: 243.2166

Ref: IN-DA0034OE

Cytarabine

CAS: 147-94-4

Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).

Fórmula: C₉H₁₃N₃O₅

Pureza: 99.83% - 99.93%

Forma y color: Fine Off-White Crystalline Powder

Peso molecular: 243.22

Ref: TM-T1272

Cytosine-β-D-arabinofuranoside

CAS: 147-94-4

Cytosine-β-D-arabinofuranoside

Fórmula: C₉H₁₃N₃O₅

Pureza: 98%

Forma y color: white crystalline powder

Peso molecular: 243.22g/mol

Ref: 54-OR1012751

Cytarabine-13C-15N2

CAS: 147-94-4

Fórmula: C₈₁₃CH₁₃N₁₅N₂O₅

Forma y color: White To Off-White Solid

Peso molecular: 246.20

Ref: 4Z-C-150002

Cytarabine

CAS: 147-94-4

Fórmula: C₉H₁₃N₃O₅

Pureza: 98.0 - 102.0 % (dried basis)

Forma y color: White crystalline powder

Peso molecular: 243.22

Ref: 7W-GP6403

Cytarabine

CAS: 147-94-4

Fórmula: C₉H₁₃N₃O₅

Forma y color: White To Off-White Solid

Peso molecular: 243.22

Ref: 4Z-C-150007

Cytarabine

CAS: 147-94-4

Cytarabine

Pureza: ≥98%

Peso molecular: 243.22g/mol

Ref: 54-BUP17828

Arabinocytosine

CAS: 147-94-4

Fórmula: C₉H₁₃N₃O₅

Pureza: 95%~99%

Peso molecular: 243.219

Ref: BP-BP3887

Cytarabine

CAS: 147-94-4, 69-74-9

Fórmula: C₉H₁₃N₃O₅

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 243.22

Ref: 3B-C2035

Cytarabine

CAS: 147-94-4

Fórmula: C₉H₁₃N₃O₅

Forma y color: Neat

Peso molecular: 243.22

Ref: 04-C11926000

Cytarabine

Producto controlado

CAS: 147-94-4

Fórmula: C₉H₁₃N₃O₅

Forma y color: Neat

Peso molecular: 243.22

Ref: 86-MM1117.00

Cytarabine-13C3

CAS: 147-94-4

Fórmula: C₆₁₃C₃H₁₃N₃O₅

Peso molecular: 246.19

Ref: 4Z-C-150001

Cytarabine

CAS: 147-94-4

Applications Cytarabine is used as an antineoplastic and antiviral. It is a selective inhibitor of DNA synthesis. Does not inhibit RNA synthesis.Cytarabine, or cytosine arabinoside, is a chemotherapy agent used mainly in the treatment of cancers of white blood cells such as acute myeloid leukemia (AML) and non-Hodgkin lymphoma. It is also known as Ara-C (Arabinofuranosyl Cytidine). It destroys cancer cells by interfering with DNA synthesis.
References Donehower, R.C., et al.: Cancer Treat. Rep., 70, 1059 (1986);

Fórmula: C₉H₁₃N₃O₅

Forma y color: Neat

Peso molecular: 243.22

Ref: TR-C998100

Cytarabine-13C3

Producto controlado

CAS: 147-94-4

Stability Hygroscopic
Applications Labelled Cytarabine, a compound used as an antineoplastic and antiviral. A selective inhibitor of DNA synthesis. Does not inhibit RNA synthesis.
References Donehower, R.C., et al.: Cancer Treat. Rep., 70, 1059 (1986)

Fórmula: C₆₁₃C₃H₁₃N₃O₅

Forma y color: Beige

Peso molecular: 246.19

Ref: TR-C998102

Cytarabine

CAS: 147-94-4

Anti-viral; anti-neoplastic

Fórmula: C₉H₁₃N₃O₅

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 243.22 g/mol

Ref: 3D-NA05771

Cytarabine - Bio-X ™

CAS: 147-94-4

Cytarabine is also known as cytosine arabinoside (ara-C) and is a chemotherapy drug that works by inhibiting DNA synthesis. It acts as a nucleoside analogue, which is incorporated into the growing DNA chain during replication. Cytarabine combines a cytosine base with an arabinose sugar (1β-arabinofuranosylcytosine) and is an analog for human deoxycytosine. Cytarabine interferes with DNA synthesis as it is rapidly converted to cytosine arabinoside triphosphate, damaging DNA when cells are in the synthesis phase (S phase). Tumor cells which are highly mitotic and growing rapidly are therefore preferably targeted. Cytarabine also inhibits nucleotide reductase enzymes as well as nuclear polymerases, leading to interruption and inhibition of synthesis, strand breaks and cell death.

Fórmula: C₉H₁₃N₃O₅

Pureza: (%) Min. 98%

Forma y color: Powder

Peso molecular: 243.22 g/mol

Ref: 3D-BA164339