CAS 147118-36-3

N-[4-(4-Fluorofenil)-5-(hidroximetil)-6-(1-metiletil)-2-pirimidinil]-N-metilmetanosulfonamida

Descripción:

N-[4-(4-Fluorofenil)-5-(hidroximetil)-6-(1-metiletil)-2-pirimidinil]-N-metilmetanosulfonamida, con número CAS 147118-36-3, es un compuesto químico que pertenece a la clase de los sulfonamidas. Esta sustancia presenta un anillo de pirimidina sustituido con varios grupos funcionales, incluyendo un grupo fluorofenilo y un grupo hidroximetilo, que contribuyen a su actividad biológica. La presencia del grupo metanosulfonamida indica aplicaciones potenciales en química medicinal, particularmente en el desarrollo de productos farmacéuticos. La estructura del compuesto sugiere que puede exhibir propiedades como la inhibición de enzimas o la modulación de vías biológicas, lo que lo convierte en un interés en el descubrimiento de fármacos. Además, el átomo de flúor puede mejorar la lipofilia y la estabilidad metabólica, que son características deseables en el diseño de fármacos. En general, las características estructurales únicas y los grupos funcionales de este compuesto lo posicionan como un candidato para una mayor investigación en aplicaciones terapéuticas, particularmente en áreas relacionadas con la oncología o enfermedades infecciosas.

Fórmula: C₁₆H₂₀FN₃O₃S

InChI: InChI=1S/C16H20FN3O3S/c1-10(2)14-13(9-21)15(11-5-7-12(17)8-6-11)19-16(18-14)20(3)24(4,22)23/h5-8,10,21H,9H2,1-4H3

Clave InChI: InChIKey=MSDYDUNHTAYBHV-UHFFFAOYSA-N

SMILES: C(O)C=1C(=NC(N(S(C)(=O)=O)C)=NC1C(C)C)C2=CC=C(F)C=C2

Sinónimos:

• (Methanol) 4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methylsulfonylamino)Pyrimidine-5-yl-Methanol
• 4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Mehyl-N-Mehylsulfonylamino)Pyrimidine-5-yl-Methanol
• 4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methanesulfonylamino) Pyrimidin-5-Methanol
• 4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methylsulfonylamino)Pyrimidine-5-Me
• 4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methylsulfonylamino)Pyrimidine-5-Methanol
• 4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-Methyl-N-Methylsulfonyl)Amino]Pyrimidin-5-Yl-Methanol
• 4-(4-Fluorophenyl)-6-isopropyl-2- [(N-methyl-N- methylsulfony)amino]pyrimidine-5-yl-methanol
• 4-(4-Fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyrimidine-5-yl-methonol
• 4-(4-Fluorophenyl)-6-isopropyl-2-[N(N-methylsuophonyl)amino]pyrimidine-5-yl-methanol
• 5-(Hydroxymethyl)-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine
• 6-(E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-methylsulfonyl-methyl pyrimidine-5-yl)vinyl)(4R,6S)-2,2-dimethyl)(1,3)-dioxane
• Methanesulfonamide, N-[4-(4-fluorophenyl)-5-(hydroxymethyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl-
• Methyl 4-(4-Fluorophenyl)6-Isopropyl-2-(N-Methyl-N-Methylsulfonyl)Amino] Pyrimidine-5-Carbixylate
• N-[4-(4-Fluorophenyl)-5-(hydroxymethyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methylmethanesulfonamide
• N-[4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide
• N-[4-(4-Fluorophenyl)-6-isopropyl-5-(hydroxymethyl)pyrimidin-2-yl]-N-methylmethanesulfonamide
• N-[4-(4-fluorophenyl)-5-(hydroxymethyl)-6-(propan-2-yl)pyrimidin-2-yl]-N-methylmethanesulfonamide
• Rosuvastatin calcium intermediate R-1-2
• Z-7
• Z7
• Zd-2
• Methyl 4-(4-Fluorophenyl)6-Isopropyl-2-(N-Methyl-N-Methylsulfonyl)Amino] Pyrimidine-5-Carbixylate(Z-7)
• 4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-n- methylsulfonyl)amino]pyrimidine-5-yl-methanol
• 4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-n-methylsulfonyl)amino] pyrimidine-5-yl-methanol

Methanesulfonamide, N-[4-(4-fluorophenyl)-5-(hydroxymethyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl-

CAS: 147118-36-3

Fórmula: C₁₆H₂₀FN₃O₃S

Pureza: 97%

Forma y color: Solid

Peso molecular: 353.4117

Ref: IN-DA001EN2

4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-Methyl-n-Methylsulfonyl)Amino]Pyrimidine-5-yl-Methanol

CAS: 147118-36-3

4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-Methyl-n-Methylsulfonyl)Amino]Pyrimidine-5-yl-Methanol

Pureza: 98%

Peso molecular: 353.41g/mol

Ref: 54-PC105229

Rosuvastatin Impurity 40

CAS: 147118-36-3

Fórmula: C₁₆H₂₀FN₃O₃S

Forma y color: White To Off-White Solid

Peso molecular: 353.41

Ref: 4Z-R-0944

4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine-5-methanol

Producto controlado

CAS: 147118-36-3

Fórmula: C₁₆H₂₀FN₃O₃S

Forma y color: Neat

Peso molecular: 353.41

Ref: 86-MM0936.02

N-[4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide

Producto controlado

CAS: 147118-36-3

Applications A Rosuvastatin (R700500) intermediate as HMG-CoA reductase inhibitor.
References Beck, et al.: J. Med. Chem., 33, 52 (1999),

Fórmula: C₁₆H₂₀FN₃O₃S

Forma y color: Neat

Peso molecular: 353.41

Ref: TR-F595380

4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsufonyl)amino]pyrimidine-5-yl-methanol

CAS: 147118-36-3

Fórmula: C₁₆H₂₀FN₃O₃S

Pureza: 97%

Forma y color: Solid

Peso molecular: 353.41

Ref: 10-F093168

N-[4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide-d6

Producto controlado

CAS: 147118-36-3

Applications N-[4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide-d6 is an isotope labelled Rosuvastatin (R700500) intermediate as HMG-CoA reductase inhibitor.
References Beck, et al.: J. Med. Chem., 33, 52 (1999),

Fórmula: C₁₆H₁₄D₆FN₃O₃S

Forma y color: Neat

Peso molecular: 359.45

Ref: TR-F595382

N-(4-(4-Fluorophenyl)-5-(hydroxymethyl)-6-isopropylpyrimidin-2-yl)-Nmethylmethanesulfonamide

CAS: 147118-36-3

Please enquire for more information about N-(4-(4-Fluorophenyl)-5-(hydroxymethyl)-6-isopropylpyrimidin-2-yl)-Nmethylmethanesulfonamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Fórmula: C₁₆H₂₀FN₃O₃S

Pureza: Min. 95%

Peso molecular: 353.41 g/mol

Ref: 3D-FF57578

Rosuvastatin Hydroxymethyl Impurity

CAS: 147118-36-3

Fórmula: C₁₆H₂₀FN₃O₃S

Peso molecular: 353.41

Ref: ST-EA-CP-R1054