CAS 149231-65-2
:N-acetil-tir-val-ala-asp 7-amido-4-*metilcumarina
Descripción:
N-acetil-tir-val-ala-asp 7-amido-4-metilcumarina, identificado por su número CAS 149231-65-2, es un compuesto sintético que pertenece a la clase de derivados peptídicos. Esta sustancia presenta una combinación de aminoácidos, específicamente N-acetiltirosina, valina, alanina y ácido aspártico, unidos en una secuencia específica. La presencia del grupo 7-amido-4-metilcumarina sugiere que tiene propiedades fluorescentes, lo que la hace útil en ensayos bioquímicos y aplicaciones de investigación, particularmente en el estudio de la actividad enzimática o interacciones proteicas. El grupo N-acetilo mejora su solubilidad y estabilidad, mientras que el componente de cumarina puede servir como un grupo reportero en varias técnicas analíticas. En general, este compuesto se caracteriza por su estructura peptídica, potencial bioactividad y utilidad en aplicaciones basadas en fluorescencia, contribuyendo a su relevancia en la investigación bioquímica y farmacéutica.
Fórmula:C33H39N5O10
Sinónimos:- Ac-Yvad-Amc
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Encontrado 4 productos.
Ac-Tyr-Val-Ala-Asp-AMC
CAS:Ac-YVAD-AMC is a fluorogenic substrate for caspase-1 (ICE). It displayed a Km of 8.5 ± 0.5 µM for recombinant human caspase-1.Fórmula:C33H39N5O10Pureza:99.3%Forma y color:White PowderPeso molecular:665.7Ac-Tyr-Val-Ala-Asp-AMC
CAS:Ac-Tyr-Val-Ala-Asp-AMC is a peptide that is used as a research tool to activate ion channels in cells and study the effects of ligands on these channels. It is also used in cell biology to study protein interactions, although it does not bind to any specific receptor. Ac-Tyr-Val-Ala-Asp-AMC belongs to the group of inhibitors and can be used for pharmacological purposes. The chemical structure of this peptide consists of a covalent bond between an amino acid and an acetylated form of a fluorescent molecule, which makes it suitable for use in fluorescence microscopy. Acetylated Tyr (Ac-Tyr) is one of the six amino acids found in proteins and has the ability to inhibit the activity of ion channels by binding to their external cavity. Acetylation at position 2 or 3 on Tyr can increase its affinity for calcium ion channels and affect their activation or deFórmula:C33H39N5O10Pureza:Min. 95%Peso molecular:665.69 g/molAc-Tyr-Val-Ala-Asp-AMC
CAS:Ac-Tyr-Val-Ala-Asp-AMC is a compound that has been shown to induce apoptotic cell death in MDA-MB-231 breast cancer cells. It inhibits the activity of proteases, which are enzymes that degrade proteins. Ac-Tyr-Val-Ala-Asp-AMC has also been shown to inhibit serine proteases and granule neurons, which are proteins in the brain that regulate the production of atp levels. Ac-Tyr-Val-Ala-Asp-AMC has also been shown to inhibit muscle cell proliferation. Acetylcholine (ACh) is a neurotransmitter responsible for signaling between nerve cells in the central nervous system and other parts of the body. Acetylcholine is synthesized by choline acetyltransferase (ChAT), an enzyme that breaks down acetylcholine into choline and acetate. Inhibition of ChAT leads to a decrease inFórmula:C33H39N5O10Pureza:Min. 95%Peso molecular:665.69 g/mol


